• 1. Establishing new scaling relations on two-dimensional MXenes for CO2 electroreduction?
  Albertus D. Handoko,Khoong Hong Khoo,Teck Leong Tan,Hongmei Jin,Zhi Wei Seh J. Mater. Chem. A, 2018,6, 21885-21890
• 2. Embedding heteroatoms: an effective approach to create porphyrin-based functional materials
  Norihito Fukui,Keisuke Fujimoto,Hideki Yorimitsu,Atsuhiro Osuka Dalton Trans., 2017,46, 13322-13341
• 3. Evidence of field induced slow magnetic relaxation in cis-[Co(hfac)2(H2O)2] exhibiting tri-axial anisotropy with a negative axial component?
  Denis V. Korchagin,Elena A. Yureva,Alexander V. Akimov,Eugenii Ya. Misochko,Gennady V. Shilov,Artem D. Talantsev,Roman B. Morgunov,Alexander A. Shakin,Sergey M. Aldoshin,Boris S. Tsukerblat Dalton Trans., 2017,46, 7540-7548
• 4. Excellent energy storage performance in NaNbO3-based relaxor antiferroeic ceramics under a low electric field
  XuxinCheng,XiaomingChen,PengyuanFan
• 5. Evolutionary de novo design of phenothiazine derivatives for dye-sensitized solar cells?
  Vishwesh Venkatraman,Marco Foscato,Vidar R. Jensen,Bj?rn K?re Alsberg J. Mater. Chem. A, 2015,3, 9851-9860

Comprehensive Overview of 4-chloro-2-(morpholin-4-yl)-1,3-thiazole-5-carboxylic acid (CAS No. 1463535-18-3)

4-chloro-2-(morpholin-4-yl)-1,3-thiazole-5-carboxylic acid (CAS No. 1463535-18-3) is a heterocyclic compound that has garnered significant attention in pharmaceutical and agrochemical research due to its unique structural features and potential applications. The compound belongs to the thiazole family, a class of organic compounds known for their diverse biological activities. The presence of both morpholine and carboxylic acid functional groups in its structure makes it a versatile intermediate for the synthesis of more complex molecules.

In recent years, the demand for thiazole derivatives has surged, driven by their widespread use in drug discovery and material science. Researchers are particularly interested in 4-chloro-2-(morpholin-4-yl)-1,3-thiazole-5-carboxylic acid due to its potential as a building block for kinase inhibitors and antimicrobial agents. Its CAS No. 1463535-18-3 is frequently searched in scientific databases, reflecting its growing importance in the field.

The compound's morpholine ring contributes to its solubility and bioavailability, making it an attractive candidate for medicinal chemistry. Meanwhile, the chloro substituent at the 4-position of the thiazole core enhances its reactivity, enabling further functionalization. These properties align with current trends in fragment-based drug design, where small molecules like 4-chloro-2-(morpholin-4-yl)-1,3-thiazole-5-carboxylic acid serve as critical starting points for optimizing drug candidates.

From an industrial perspective, the synthesis of 4-chloro-2-(morpholin-4-yl)-1,3-thiazole-5-carboxylic acid involves multi-step organic reactions, often requiring precise control of reaction conditions to achieve high yields. Its CAS No. 1463535-18-3 is commonly referenced in patent literature, highlighting its role in the development of novel therapeutics. The compound's stability under various pH conditions further broadens its applicability in formulation science.

Environmental and regulatory considerations are also key topics surrounding this compound. As the pharmaceutical industry shifts toward green chemistry, researchers are exploring sustainable methods to produce thiazole derivatives like 4-chloro-2-(morpholin-4-yl)-1,3-thiazole-5-carboxylic acid. Questions such as "How to optimize the synthesis of CAS No. 1463535-18-3?" or "What are the latest applications of morpholine-containing thiazoles?" are frequently encountered in academic and industrial forums.

In summary, 4-chloro-2-(morpholin-4-yl)-1,3-thiazole-5-carboxylic acid (CAS No. 1463535-18-3) represents a promising scaffold in modern chemistry. Its structural versatility, combined with its relevance to drug discovery and material science, ensures its continued prominence in scientific research. As advancements in computational chemistry and high-throughput screening accelerate, this compound is likely to play an even greater role in addressing unmet medical and industrial needs.

• 332062-08-5(Fmoc-S-3-amino-4,4-diphenyl-butyric acid)
• 1270529-38-8(1,2,3,4,5,6-Hexahydro-[2,3]bipyridinyl-6-ol)
• 2680771-01-9(4-cyclopentyl-3-{(prop-2-en-1-yloxy)carbonylamino}butanoic acid)
• 2098070-20-1(2-(3-(Pyridin-3-yl)-1H-pyrazol-1-yl)acetimidamide)
• 1444113-98-7(N-(3-cyanothiolan-3-yl)-2-[(2,2,2-trifluoroethyl)sulfanyl]pyridine-4-carboxamide)
• 941977-17-9(N'-(3-chloro-2-methylphenyl)-N-2-(dimethylamino)-2-(naphthalen-1-yl)ethylethanediamide)
• 2138166-62-6(2,2-Difluoro-3-[methyl(2-methylbutyl)amino]propanoic acid)
• 89640-58-4(2-Iodo-4-nitrophenylhydrazine)
• 1449132-38-0(3-Fluoro-5-(2-fluoro-5-methylbenzylcarbamoyl)benzeneboronic acid)
• 2034271-14-0(2-(1H-indol-3-yl)-N-{[6-(thiophen-2-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]methyl}acetamide)