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• 2. Exceptional activity of sub-nm Pt clusters on CdS for photocatalytic hydrogen production: a combined experimental and first-principles study?
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• 3. Fate of Sb(v) and Sb(iii) species along a gradient of pH and oxygen concentration in the Carnoulès mine waters (Southern France)
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• 4. Evidence that the availability of an allylic hydrogen governs the regioselectivity of the Wacker oxidation
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• 5. Etching of glass microchips with supercritical water?
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• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Benzyloxycarbonyls

Compound CAS No. 146119-53-1: 2-{(Benzyloxy)Carbonyl(2-Methoxyethyl)Amino}Acetic Acid

2-{(Benzyloxy)Carbonyl(2-Methoxyethyl)Amino}Acetic Acid (CAS No. 146119-53-1) is a versatile organic compound with significant applications in the fields of chemistry and pharmacology. This compound, often abbreviated as Boc-(2-methoxyethyl)-Gly-OH, belongs to the class of amino acids modified with protective groups. Its structure features a benzyloxycarbonyl (Boc) group attached to the amino terminus of glycine, with a 2-methoxyethyl substituent further modifying the Boc group. This unique structure makes it an ideal candidate for various synthetic and therapeutic purposes.

The synthesis of Boc-(2-methoxyethyl)-Gly-OH involves multi-step chemical reactions, typically starting from glycine and progressing through protection and substitution reactions. The Boc group is widely used in peptide synthesis as a temporary protecting group for amino functionalities, ensuring selective reactivity during complex syntheses. The presence of the 2-methoxyethyl substituent enhances the compound's stability and solubility, making it suitable for use in aqueous environments. Recent studies have highlighted its potential as an intermediate in the synthesis of bioactive molecules, particularly in the development of novel peptide-based drugs.

One of the most promising applications of Boc-(2-methoxyethyl)-Gly-OH lies in its role as a building block in medicinal chemistry. Researchers have utilized this compound to construct peptide libraries, which are essential for high-throughput screening in drug discovery. The ability to precisely control the stereochemistry and functional groups during synthesis has made this compound invaluable in creating molecules with desired pharmacokinetic properties. For instance, studies published in *Journal of Medicinal Chemistry* have demonstrated its utility in designing inhibitors for proteolytic enzymes, a key target in cancer therapy.

In addition to its role in peptide synthesis, Boc-(2-methoxyethyl)-Gly-OH has been explored for its potential in materials science. Its ability to form self-assembled monolayers (SAMs) on various substrates has been investigated for applications in surface modification and nanotechnology. Recent advancements reported in *Advanced Materials* have shown that SAMs derived from this compound exhibit excellent biocompatibility and mechanical stability, making them suitable for biosensor development and tissue engineering.

The chemical stability and functional versatility of Boc-(2-methoxyethyl)-Gly-OH also make it an attractive candidate for use in diagnostic reagents. Its ability to undergo selective cleavage under specific conditions allows for its application in immunoassays and other analytical techniques. A study published in *Analytical Chemistry* highlighted its use as a linker molecule in enzyme-linked immunosorbent assays (ELISAs), where it significantly improved assay sensitivity and specificity.

Looking ahead, the demand for Boc-(2-methoxyethyl)-Gly-OH is expected to grow as researchers continue to uncover its potential across diverse fields. Its compatibility with green chemistry principles, including the use of mild reaction conditions and recyclable catalysts, aligns with current trends toward sustainable chemical practices. Furthermore, ongoing research into its biodegradability and environmental impact is expected to pave the way for its broader adoption in industrial applications.

In conclusion, Boc-(2-methoxyethyl)-Gly-OH (CAS No. 146119-53-1) stands out as a multifaceted compound with immense potential across various scientific domains. Its unique structure, combined with recent advancements in synthetic methodologies and application studies, positions it as a key player in future innovations within chemistry and pharmacology.

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