Cas no 145625-71-4 (4-(2-aminoethyl)piperazin-2-one)

4-(2-Aminoethyl)piperazin-2-one is a heterocyclic compound featuring both an aminoethyl side chain and a piperazinone core, making it a versatile intermediate in organic synthesis and pharmaceutical applications. Its bifunctional structure allows for further derivatization, enabling the formation of amides, ureas, or other targeted modifications. The compound’s piperazinone ring provides a rigid scaffold, which can enhance binding affinity in drug design, while the aminoethyl group offers a reactive handle for conjugation or functionalization. This makes it particularly useful in the development of biologically active molecules, such as kinase inhibitors or receptor modulators. Its stability and synthetic flexibility underscore its utility in medicinal chemistry and material science research.
4-(2-aminoethyl)piperazin-2-one structure
145625-71-4 structure
Product Name:4-(2-aminoethyl)piperazin-2-one
CAS No:145625-71-4
MF:C6H13N3O
MW:143.186920881271
CID:101535
PubChem ID:7175991
Update Time:2025-05-28

4-(2-aminoethyl)piperazin-2-one Chemical and Physical Properties

Names and Identifiers

    • 2-Piperazinone,4-(2-aminoethyl)-
    • 4-(2-aminoethyl)piperazin-2-one
    • 4-(2-AMINO-ETHYL)-PIPERAZIN-2-ONE DIHYDROCHLORIDE
    • 2-Piperazinone,4-(2-aminoethyl)
    • 4-(2-Amino-ethyl)-piperazin-2-one
    • MFCD06740255
    • 2-Piperazinone, 4-(2-aminoethyl)-
    • AKOS000145377
    • 4-(2-amino-ethyl)-piperazin-2-one, AldrichCPR
    • FT-0723648
    • DTXSID50428331
    • AT13739
    • EN300-129820
    • CHEMBL4563865
    • KMMBJDNXKWZSLX-UHFFFAOYSA-N
    • SCHEMBL2239001
    • CS-0374533
    • 145625-71-4
    • F2158-0110
    • DA-10184
    • Inchi： 1S/C6H13N3O/c7-1-3-9-4-2-8-6(10)5-9/h1-5,7H2,(H,8,10)
    • InChI Key： KMMBJDNXKWZSLX-UHFFFAOYSA-N
    • SMILES： O=C1CN(CCN)CCN1

Computed Properties

  • Exact Mass: 143.10600
  • Monoisotopic Mass: 143.105862
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 10
  • Rotatable Bond Count: 2
  • Complexity: 126
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 58.4
  • XLogP3: -1.6

Experimental Properties

  • PSA: 58.36000
  • LogP: -0.65610

4-(2-aminoethyl)piperazin-2-one Security Information

  • Hazard Category Code： 36
  • Safety Instruction： 26
  • Hazardous Material Identification： Xi

4-(2-aminoethyl)piperazin-2-one Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
TRC
A595438-10mg
4-(2-aminoethyl)piperazin-2-one
 145625-71-4
10mg
 $ 70.00 2022-06-08
TRC
A595438-50mg
4-(2-aminoethyl)piperazin-2-one
 145625-71-4
50mg
 $ 230.00 2022-06-08
TRC
A595438-100mg
4-(2-aminoethyl)piperazin-2-one
 145625-71-4
100mg
 $ 340.00 2022-06-08
Enamine
EN300-129820-0.05g
4-(2-aminoethyl)piperazin-2-one
 145625-71-4 95.0%
0.05g
 $149.0 2025-02-21
Enamine
EN300-129820-0.1g
4-(2-aminoethyl)piperazin-2-one
 145625-71-4 95.0%
0.1g
 $221.0 2025-02-21
Enamine
EN300-129820-0.25g
4-(2-aminoethyl)piperazin-2-one
 145625-71-4 95.0%
0.25g
 $315.0 2025-02-21
Enamine
EN300-129820-0.5g
4-(2-aminoethyl)piperazin-2-one
 145625-71-4 95.0%
0.5g
 $501.0 2025-02-21
Enamine
EN300-129820-1.0g
4-(2-aminoethyl)piperazin-2-one
 145625-71-4 95.0%
1.0g
 $642.0 2025-02-21
Enamine
EN300-129820-2.5g
4-(2-aminoethyl)piperazin-2-one
 145625-71-4 95.0%
2.5g
 $1260.0 2025-02-21
Enamine
EN300-129820-5.0g
4-(2-aminoethyl)piperazin-2-one
 145625-71-4 95.0%
5.0g
 $1862.0 2025-02-21

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