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Comprehensive Overview of 2-Bromo-3-butylthiophene (CAS No. 145543-82-4): Properties, Applications, and Industry Insights

2-Bromo-3-butylthiophene (CAS No. 145543-82-4) is a specialized organic compound belonging to the thiophene derivatives family, widely recognized for its versatility in synthetic chemistry and material science. With the increasing demand for heterocyclic compounds in pharmaceuticals, agrochemicals, and advanced materials, this brominated thiophene derivative has garnered significant attention. Its molecular structure combines a bromo substituent at the 2-position and a butyl group at the 3-position, offering unique reactivity patterns for cross-coupling reactions and polymer synthesis.

The compound’s CAS number 145543-82-4 serves as a critical identifier in regulatory and commercial databases, ensuring precise tracking in supply chains. Researchers and manufacturers frequently search for terms like "2-Bromo-3-butylthiophene synthesis", "CAS 145543-82-4 applications", or "thiophene derivatives in organic electronics", reflecting its relevance in cutting-edge fields. Recent trends highlight its role in organic semiconductors and conductive polymers, aligning with the global push for sustainable energy solutions and flexible electronics.

From a synthetic perspective, 2-Bromo-3-butylthiophene is a pivotal intermediate in palladium-catalyzed reactions, such as Suzuki-Miyaura or Stille couplings, which are foundational in constructing complex π-conjugated systems. These systems are essential for developing OLEDs (Organic Light-Emitting Diodes) and solar cell materials. Industry professionals often inquire about "scalable synthesis methods for brominated thiophenes" or "thermal stability of 3-butylthiophene derivatives", underscoring the need for optimized production protocols.

Environmental and safety considerations are also prominent in discussions about CAS 145543-82-4. While the compound is not classified as hazardous under major regulatory frameworks, proper handling guidelines emphasize the use of personal protective equipment (PPE) and ventilated workspaces. Searches for "green chemistry alternatives for brominated intermediates" reflect the industry’s shift toward eco-friendly synthetic routes, though 2-Bromo-3-butylthiophene remains irreplaceable in certain high-performance applications.

In the pharmaceutical sector, thiophene-based scaffolds derived from this compound are explored for their bioactive potential, particularly in kinase inhibition and antimicrobial agents. Queries like "drug discovery using 3-butylthiophene motifs" or "bromothiophene pharmacokinetics" indicate growing interdisciplinary interest. Meanwhile, material scientists focus on its electrochemical properties, with publications often citing its utility in conductive inks and sensor technologies.

The commercial availability of 2-Bromo-3-butylthiophene is supported by specialized chemical suppliers, with pricing influenced by purity grades (e.g., >98% HPLC) and batch scalability. Procurement-related searches such as "bulk suppliers of CAS 145543-82-4" or "cost-effective bromothiophene derivatives" highlight its market dynamics. Analytical techniques like GC-MS, NMR, and HPLC are routinely employed for quality verification, ensuring compliance with industry standards.

Looking ahead, innovations in catalysis and flow chemistry are expected to enhance the efficiency of 2-Bromo-3-butylthiophene production. As sustainable technologies gain traction, its derivatives may play a key role in biodegradable electronics or energy storage systems. This aligns with frequent searches for "future of thiophene chemistry" and "emerging applications of brominated heterocycles", signaling a robust trajectory for this compound in both academic and industrial realms.

• 149703-84-4(2,5-Dibromo-3-octylthiophene)
• 144012-09-9(2-Bromo-3-decylthiophene)
• 148256-63-7(2,5-Dibromo-3-dodecylthiophene)
• 827343-18-0(Thiophene, 2-bromo-3-octadecyl-)
• 69249-61-2(2-Bromo-3-hexylthiophene)
• 116971-11-0(2,5-Dibromo-3-hexylthiophene)
• 116971-10-9(2,5-Dibromo-3-butylthiophene)
• 139100-06-4(2-Bromo-3-dodecylthiophene)
• 145543-83-5(2-Bromo-3-octylthiophene)
• 158956-23-1(2,5-Dibromo-3-decylthiophene)