Cas no 145383-72-8 (4-Chloro-1,3-thiazole-5-carbonitrile)
4-Chloro-1,3-thiazole-5-carbonitrile is a heterocyclic organic compound featuring a chloro-substituted thiazole ring with a nitrile functional group at the 5-position. This structure imparts reactivity suitable for diverse synthetic applications, particularly in pharmaceuticals and agrochemicals. The chloro group offers a versatile handle for nucleophilic substitution, while the nitrile functionality enables further derivatization, such as hydrolysis or cyclization. Its stability under standard conditions and compatibility with common reaction conditions make it a valuable intermediate in medicinal chemistry and material science. The compound is typically handled under inert conditions to preserve its integrity. Purity and precise characterization are critical for ensuring reproducibility in downstream applications.
145383-72-8 structure
Product Name:4-Chloro-1,3-thiazole-5-carbonitrile
CAS No:145383-72-8
MF:C4HClN2S
MW:144.582137823105
CID:101674
PubChem ID:19935346
Update Time:2025-06-07
4-Chloro-1,3-thiazole-5-carbonitrile Chemical and Physical Properties
Names and Identifiers
-
- 4-chloro-5-Thiazolecarbonitrile
- 5-Thiazolecarbonitrile,4-chloro-
- 4-Chloro-5-cyanothiazole
- 4-chlorothiazole-5-carbonitrile
- 5-Thiazolecarbonitrile, 4-chloro-
- EN300-128276
- AT15032
- 145383-72-8
- AKOS024048917
- SCHEMBL859617
- 4-chloro-1,3-thiazole-5-carbonitrile
- 4-Chloro-1,3-thiazole-5-carbonitrile
-
- Inchi： 1S/C4HClN2S/c5-4-3(1-6)8-2-7-4/h2H
- InChI Key： FNBXWKKRGNMGQJ-UHFFFAOYSA-N
- SMILES： ClC1=C(C#N)SC=N1
Computed Properties
- Exact Mass: 143.95503
- Monoisotopic Mass: 143.955
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 0
- Hydrogen Bond Acceptor Count: 3
- Heavy Atom Count: 8
- Rotatable Bond Count: 0
- Complexity: 129
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Topological Polar Surface Area: 64.9A^2
- XLogP3: 2
Experimental Properties
- PSA: 36.68
4-Chloro-1,3-thiazole-5-carbonitrile Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Alichem | A059000352-250mg |
4-Chloro-5-cyanothiazole |
145383-72-8 | 98% | 250mg |
$456.93 | 2022-04-02 | |
| Alichem | A059000352-500mg |
4-Chloro-5-cyanothiazole |
145383-72-8 | 98% | 500mg |
$661.84 | 2022-04-02 | |
| Alichem | A059000352-1g |
4-Chloro-5-cyanothiazole |
145383-72-8 | 98% | 1g |
$840.78 | 2022-04-02 | |
| TRC | B423798-10mg |
4-Chloro-1,3-thiazole-5-carbonitrile |
145383-72-8 | 10mg |
$ 70.00 | 2022-06-07 | ||
| TRC | B423798-50mg |
4-Chloro-1,3-thiazole-5-carbonitrile |
145383-72-8 | 50mg |
$ 250.00 | 2022-06-07 | ||
| TRC | B423798-100mg |
4-Chloro-1,3-thiazole-5-carbonitrile |
145383-72-8 | 100mg |
$ 365.00 | 2022-06-07 | ||
| A2B Chem LLC | AE96451-10g |
4-Chloro-5-cyanothiazole |
145383-72-8 | 95% | 10g |
$4820.00 | 2024-04-20 | |
| A2B Chem LLC | AE96451-50mg |
4-Chloro-5-cyanothiazole |
145383-72-8 | 95% | 50mg |
$293.00 | 2024-04-20 | |
| A2B Chem LLC | AE96451-100mg |
4-Chloro-5-cyanothiazole |
145383-72-8 | 95% | 100mg |
$421.00 | 2024-04-20 | |
| A2B Chem LLC | AE96451-250mg |
4-Chloro-5-cyanothiazole |
145383-72-8 | 95% | 250mg |
$587.00 | 2024-04-20 |
4-Chloro-1,3-thiazole-5-carbonitrile Related Literature
-
Xiao Liu,Jun Xu,Yinyun Lv,Wenyu Wu,Weisheng Liu,Yu Tang Dalton Trans., 2013,42, 9840-9846
-
Yaqing Liu,Jiangtao Ren,Jing Li,Jiyang Liu,Erkang Wang Chem. Commun., 2012,48, 802-804
-
Chongyang Zhu,Xiaojia Bian,Xin Jia,Ning Tang,Yongqiang Cheng Food Funct., 2020,11, 10635-10644
-
Xin Fu,Qing-rong Liang,Rong-guang Luo,Yan-shu Li,Xiao-ping Xiao,Lu-lu Yu,Wen-zhe Shan,Guang-qin Fan J. Mater. Chem. B, 2019,7, 3088-3099
-
Yang Chen,Di Zhou,Zheyi Meng,Jin Zhai Chem. Commun., 2016,52, 10020-10023
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