Cas no 145255-19-2 (5-Aminopyridine-2-carboxamide)

5-Aminopyridine-2-carboxamide is a heterocyclic organic compound featuring both an amino and a carboxamide functional group on a pyridine scaffold. This structure imparts versatility in synthetic applications, particularly as a building block in pharmaceuticals and agrochemicals. The presence of reactive sites enables further derivatization, facilitating the development of biologically active molecules. Its stability under standard conditions and compatibility with common organic solvents enhance its utility in multi-step synthesis. The compound is often employed in the preparation of kinase inhibitors and other therapeutic agents due to its ability to interact with biological targets. High purity grades are available to ensure reproducibility in research and industrial processes.
5-Aminopyridine-2-carboxamide structure
5-Aminopyridine-2-carboxamide structure
Product Name:5-Aminopyridine-2-carboxamide
CAS No:145255-19-2
MF:C6H7N3O
MW:137.139280557632
MDL:MFCD09879701
CID:64918
PubChem ID:10464392
Update Time:2025-06-09

5-Aminopyridine-2-carboxamide Chemical and Physical Properties

Names and Identifiers

    • 5-Aminopyridine-2-carboxamide
    • 2-Pyridinecarboxamide,5-amino
    • 5-amino-2-pyridinecarboxamide
    • 5-aminopicolinamide
    • 5-aminopyridine-2-carboxylic acid amide
    • 2-Pyridinecarboxamide,5-amino-(9CI)
    • 2-Pyridinecarboxamide, 5-amino-
    • 2-Pyridinecarboxamide,5-amino-
    • PubChem17853
    • CSHTYFRLFVBNHB-UHFFFAOYSA-N
    • VP13838
    • BC228144
    • 5-Amino-pyridine-2-carboxylic acid amide
    • AB0022332
    • W3172
    • 4CH
    • AMY10959
    • 145255-19-2
    • AKOS006283197
    • MFCD09879701
    • CS-W022291
    • AC-23710
    • FT-0603745
    • DTXSID10440251
    • Z1116403989
    • GS-3999
    • A26265
    • EN300-109681
    • SCHEMBL1831265
    • 5-AMino-2-pyridine carboxaMide
    • 5-AMINOPYRIDINE-2-CARBOXAMIDE,PURITY:95% MIN(HPLC)
    • CHEMBL5281955
    • BDBM50613256
    • MDL: MFCD09879701
    • Inchi: 1S/C6H7N3O/c7-4-1-2-5(6(8)10)9-3-4/h1-3H,7H2,(H2,8,10)
    • InChI Key: CSHTYFRLFVBNHB-UHFFFAOYSA-N
    • SMILES: O=C(C1C=CC(=CN=1)N)N

Computed Properties

  • Exact Mass: 137.05900
  • Monoisotopic Mass: 137.058911855g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 10
  • Rotatable Bond Count: 1
  • Complexity: 137
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 82
  • XLogP3: -0.6

Experimental Properties

  • Density: 1.323
  • Boiling Point: 427.311°C at 760 mmHg
  • Flash Point: 212.23°C
  • Refractive Index: 1.644
  • PSA: 82.00000
  • LogP: 1.04420

5-Aminopyridine-2-carboxamide Customs Data

  • HS CODE:2933399090
  • Customs Data:

    China Customs Code:

    2933399090

    Overview:

    2933399090. Other compounds with non fused pyridine rings in structure. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%

    Declaration elements:

    Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date

    Summary:

    2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

5-Aminopyridine-2-carboxamide Pricemore >>

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5-Aminopyridine-2-carboxamide Production Method

Additional information on 5-Aminopyridine-2-carboxamide

Introduction to CAS No. 145255-19-2: 5-Aminopyridine-2-carboxamide

CAS No. 145255-19-2, commonly referred to as 5-Aminopyridine-2-carboxamide, is a compound of significant interest in the fields of organic chemistry and pharmaceutical research. This compound belongs to the class of pyridine derivatives, which are widely studied for their diverse applications in drug design, agrochemicals, and materials science. The structure of 5-Aminopyridine-2-carboxamide consists of a pyridine ring with an amino group at position 5 and a carboxamide group at position 2, making it a versatile scaffold for further functionalization.

The synthesis of CAS No. 145255-19-2 involves a series of well-established organic reactions, including nucleophilic substitutions and amide bond formations. Recent advancements in catalytic methods have enabled the efficient and selective synthesis of this compound, reducing production costs and improving yield. Researchers have also explored the use of microwave-assisted synthesis and continuous flow reactors to optimize the production process, aligning with the growing demand for sustainable chemical manufacturing practices.

5-Aminopyridine-2-carboxamide has demonstrated potential in several therapeutic areas. For instance, studies have shown that this compound exhibits inhibitory activity against certain enzymes involved in inflammatory pathways, making it a promising candidate for anti-inflammatory drug development. Additionally, its ability to modulate ion channels has been explored in the context of treating neurological disorders such as epilepsy and chronic pain.

In the agricultural sector, CAS No. 145255-19-2 has been investigated for its potential as a herbicide or fungicide. Recent research highlights its effectiveness in inhibiting key enzymes responsible for plant pathogen growth, suggesting its role in developing eco-friendly crop protection agents. Moreover, the compound's stability under various environmental conditions makes it suitable for field applications.

The pharmacokinetic properties of 5-Aminopyridine-2-carboxamide have been extensively studied to evaluate its bioavailability and metabolic profile. Preclinical studies indicate that the compound exhibits moderate absorption rates and favorable distribution characteristics, which are critical factors for its potential use as an orally administered drug. Furthermore, its metabolic pathways have been mapped using advanced metabolomics techniques, providing insights into its safety profile and toxicity mechanisms.

Recent breakthroughs in computational chemistry have enabled researchers to predict the binding affinities of CAS No. 145255-19-2 with various biological targets with high accuracy. Machine learning algorithms have been employed to identify novel targets for this compound, expanding its potential applications beyond traditional therapeutic areas. These computational approaches not only accelerate drug discovery but also reduce the reliance on time-consuming experimental methods.

In conclusion, CAS No. 145255-19-2 (5-Aminopyridine-2-carboxamide) stands out as a multifaceted compound with promising applications across multiple industries. Its unique chemical structure, coupled with advancements in synthetic methodologies and computational tools, positions it as a valuable asset in both academic research and industrial development.

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