Cas no 1451393-51-3 (2-Fluoro-3-carboxypyridine-5-boronic acid)
2-Fluoro-3-carboxypyridine-5-boronic acid is a versatile boronic acid derivative widely used in Suzuki-Miyaura cross-coupling reactions, a key method for forming carbon-carbon bonds in organic synthesis. The presence of both a boronic acid group and a carboxyl functionality enhances its reactivity and selectivity, making it valuable for constructing complex heterocyclic frameworks. The fluorine substituent further modulates electronic properties, improving stability and reaction efficiency. This compound is particularly useful in pharmaceutical and agrochemical research, where precise functionalization of pyridine scaffolds is required. Its high purity and well-defined structure ensure consistent performance in demanding synthetic applications.
1451393-51-3 structure
Product Name:2-Fluoro-3-carboxypyridine-5-boronic acid
CAS No:1451393-51-3
MF:C6H5BFNO4
MW:184.917605161667
MDL:MFCD13181650
CID:4733604
Update Time:2025-06-07
2-Fluoro-3-carboxypyridine-5-boronic acid Chemical and Physical Properties
Names and Identifiers
-
- 2-Fluoro-3-carboxypyridine-5-boronic acid
- 5-Borono-2-fluoronicotinic acid
- BC001618
- Z1339
- 5-CARBOXY-6-FLUOROPYRIDINE-3-BORONIC ACID
-
- MDL： MFCD13181650
- Inchi： 1S/C6H5BFNO4/c8-5-4(6(10)11)1-3(2-9-5)7(12)13/h1-2,12-13H,(H,10,11)
- InChI Key： NINXDEFTKZXEEA-UHFFFAOYSA-N
- SMILES： FC1=C(C(=O)O)C=C(B(O)O)C=N1
Computed Properties
- Hydrogen Bond Donor Count: 3
- Hydrogen Bond Acceptor Count: 6
- Heavy Atom Count: 13
- Rotatable Bond Count: 2
- Complexity: 203
- Topological Polar Surface Area: 90.6
Experimental Properties
- Density: 1.6±0.1 g/cm3
- Boiling Point: 475.0±55.0 °C at 760 mmHg
- Flash Point: 241.1±31.5 °C
- Vapor Pressure: 0.0±1.2 mmHg at 25°C
2-Fluoro-3-carboxypyridine-5-boronic acid Security Information
- Signal Word：warning
- Hazard Statement： H303May be harmful if swallowed+H313Skin contact may be harmful+H333Inhalation may be harmful to the body
- Warning Statement： P264+P280+P305+P351+P338+P337+P313
- Safety Instruction： H303+H313+H333
- Storage Condition：storage at -4℃ (1-2weeks), longer storage period at -20℃ (1-2years)
2-Fluoro-3-carboxypyridine-5-boronic acid Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| TRC | B702993-1g |
5-Borono-2-fluoro-pyridine-3-carboxylic acid |
1451393-51-3 | 1g |
$ 50.00 | 2022-06-06 | ||
| TRC | B702993-5g |
5-Borono-2-fluoro-pyridine-3-carboxylic acid |
1451393-51-3 | 5g |
$ 65.00 | 2022-06-06 | ||
| TRC | B702993-10g |
5-Borono-2-fluoro-pyridine-3-carboxylic acid |
1451393-51-3 | 10g |
$ 80.00 | 2022-06-06 | ||
| Matrix Scientific | 206141-1g |
5-Borono-2-fluoropyridine-3-carboxylic acid |
1451393-51-3 | 1g |
$1570.00 | 2023-09-07 | ||
| Matrix Scientific | 206141-25g |
5-Borono-2-fluoropyridine-3-carboxylic acid |
1451393-51-3 | 25g |
$7117.00 | 2023-09-07 | ||
| Chemenu | CM210040-1g |
5-Borono-2-fluoronicotinic acid |
1451393-51-3 | 97% | 1g |
$353 | 2022-09-02 | |
| NAN JING YAO SHI KE JI GU FEN Co., Ltd. | PBEB10187-100mg |
2-fluoro-3-carboxypyridine-5-boronic acid |
1451393-51-3 | 95% | 100mg |
￥594.0 | 2024-04-24 | |
| NAN JING YAO SHI KE JI GU FEN Co., Ltd. | PBEB10187-250mg |
2-fluoro-3-carboxypyridine-5-boronic acid |
1451393-51-3 | 95% | 250mg |
￥951.0 | 2024-04-24 | |
| NAN JING YAO SHI KE JI GU FEN Co., Ltd. | PBEB10187-500mg |
2-fluoro-3-carboxypyridine-5-boronic acid |
1451393-51-3 | 95% | 500mg |
￥1584.0 | 2024-04-24 | |
| NAN JING YAO SHI KE JI GU FEN Co., Ltd. | PBEB10187-1g |
2-fluoro-3-carboxypyridine-5-boronic acid |
1451393-51-3 | 95% | 1g |
￥2376.0 | 2024-04-24 |
2-Fluoro-3-carboxypyridine-5-boronic acid Related Literature
-
J. Matthew Kurley,Phillip W. Halstenberg,Abbey McAlister,Stephen Raiman,Richard T. Mayes RSC Adv., 2019,9, 25602-25608
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Jason Y. C. Lim,Yong Yu,Guorui Jin,Kai Li,Yi Lu,Jianping Xie Nanoscale Adv., 2020,2, 3921-3932
-
Zhiyan Chen,Nan Wu,Yaobing Wang,Bing Wang,Yingde Wang J. Mater. Chem. A, 2018,6, 516-526
-
Olga Guselnikova,Gérard Audran,Jean-Patrick Joly,Andrii Trelin,Evgeny V. Tretyakov,Vaclav Svorcik,Oleksiy Lyutakov,Sylvain R. A. Marque Chem. Sci., 2021,12, 4154-4161
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