Cas no 1448-87-9 (2-Chloroquinoxaline)

2-Chloroquinoxaline is a heterocyclic aromatic compound featuring a quinoxaline core substituted with a chlorine atom at the 2-position. This versatile intermediate is widely used in organic synthesis, particularly in the preparation of pharmaceuticals, agrochemicals, and specialty chemicals. Its reactive chlorine site enables efficient nucleophilic substitution reactions, facilitating the introduction of diverse functional groups. The compound’s stability and compatibility with various reaction conditions make it a valuable building block for constructing complex molecular architectures. Additionally, 2-chloroquinoxaline serves as a precursor for biologically active compounds, including antimicrobial and anticancer agents. Its high purity and consistent performance ensure reliable results in research and industrial applications.

2-Chloroquinoxaline structure

Product Name:2-Chloroquinoxaline

CAS No:1448-87-9

MF:C₈H₅ClN₂

MW:164.591700315475

MDL:MFCD00043907

CID:41377

PubChem ID:238938

Update Time:2025-05-19

2-Chloroquinoxaline Chemical and Physical Properties

Names and Identifiers

- 2-Chloroquinoxaline
- 2-chloranylquinoxaline
- 2-chloro-benzopyrazine
- 2-chloro-quinoxaline
- 2-chloroquinoxalinone
- 3-chloroquinoxaline
- 3-cyclohexylquinoxaline
- chloroquinoxaline
- Quinoxaline,2-chloro
- NSC 43553
- Quinoxaline, 2-chloro-
- 2-Chloroquinoxaline 98%
- 2-Chloroquinoxaline ,99%
- 2-Chloroquinoxaline, 97%+
- E9X60Z79BG
- BYHVGQHIAFURIL-UHFFFAOYSA-N
- Quinoxalyl chloride
- NSC43553
- 2-chloro quinoxaline
- PubChem15447
- KSC181I0T
- Jsp002628
- BCP27153
- SBB05460
- EINECS 215-905-8
- 10.14272/BYHVGQHIAFURIL-UHFFFAOYSA-N.2
- FT-0633549
- W-108147
- MFCD00043907
- 1D-008
- F1903-0389
- BP-12281
- A811315
- BB 0218371
- Q27277055
- doi:10.14272/BYHVGQHIAFURIL-UHFFFAOYSA-N.1
- SCHEMBL222284
- NS00044126
- EN300-27591
- NSC-43553
- AC-14658
- 2-Chloroquinoxaline, 98%
- 1448-87-9
- SY014068
- Z240126804
- CS-W016083
- AM20070313
- DTXSID20932415
- doi:10.14272/BYHVGQHIAFURIL-UHFFFAOYSA-N.2
- PB40703
- QUINOXALINE, 2-CHLORO
- 10.14272/BYHVGQHIAFURIL-UHFFFAOYSA-N.1
- doi:10.14272/BYHVGQHIAFURIL-UHFFFAOYSA-N.3
- UNII-E9X60Z79BG
- AKOS002665691
- H10060
- C3492
- BBL100055
- STL186141
- DTXCID301361107
- DB-000848
- 215-905-8
- MDL： MFCD00043907
- Inchi： 1S/C8H5ClN2/c9-8-5-10-6-3-1-2-4-7(6)11-8/h1-5H
- InChI Key： BYHVGQHIAFURIL-UHFFFAOYSA-N
- SMILES： ClC1=CN=C2C=CC=CC2=N1

Computed Properties

Exact Mass: 164.01400
Monoisotopic Mass: 164.014
Isotope Atom Count: 0
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 2
Heavy Atom Count: 11
Rotatable Bond Count: 0
Complexity: 140
Covalently-Bonded Unit Count: 1
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count : 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
XLogP3: 2.2
Topological Polar Surface Area: 25.8
Surface Charge: 0
Tautomer Count: nothing

Experimental Properties

Color/Form: Similar to white crystals
Density: 1.2847 (rough estimate)
Melting Point: 46.0 to 50.0 deg-C
Boiling Point: 100°C/1.4mmHg(lit.)
Flash Point: >110 oC
Refractive Index: 1.5500 (estimate)
PSA: 25.78000
LogP: 2.28320
Solubility: Not determined
λmax: 346(EtOH)(lit.)

2-Chloroquinoxaline Security Information

Symbol:
Prompt：warning
Signal Word：Danger
Hazard Statement： H301-H315-H319-H335
Warning Statement： P261-P301 + P310-P305 + P351 + P338
Hazardous Material transportation number：UN 2811 6.1/PG 3
WGK Germany：3
Hazard Category Code： 22-36/37/38
Safety Instruction： S26-S36/37/39-S45
Hazardous Material Identification：
Risk Phrases：R25; R36/37/38
HazardClass：IRRITANT
Storage Condition：Inert atmosphere,2-8°C
Safety Term：S26;S36/37/39;S45

2-Chloroquinoxaline Customs Data

HS CODE：2933990090
Customs Data：

China Customs Code:
2933990090

Overview:

2933990090. Other heterocyclic compounds containing only nitrogen heteroatoms. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%

Declaration elements:

Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date

Summary:

2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

2-Chloroquinoxaline Pricemore >>

Related Categories	No.	Product Name	Cas No.	Purity	Specification	Price	update time
Alichem	A449038599-100g	2-Chloroquinoxaline	1448-87-9	98%	100g	318.15 USD	2021-06-15
Ambeed	A160115-250mg	2-Chloroquinoxaline	1448-87-9	98%	250mg	$5.0	2025-02-24
Ambeed	A160115-1g	2-Chloroquinoxaline	1448-87-9	98%	1g	$6.0	2025-02-24
Ambeed	A160115-5g	2-Chloroquinoxaline	1448-87-9	98%	5g	$12.0	2025-02-24
Ambeed	A160115-10g	2-Chloroquinoxaline	1448-87-9	98%	10g	$21.0	2025-02-24
Ambeed	A160115-25g	2-Chloroquinoxaline	1448-87-9	98%	25g	$34.0	2025-02-24
Ambeed	A160115-100g	2-Chloroquinoxaline	1448-87-9	98%	100g	$106.0	2025-02-24
BAI LING WEI Technology Co., Ltd.	222674-1G	2-Chloroquinoxaline, 99%	1448-87-9	99%	1G	￥ 200	2022-04-26
SHANG HAI XIAN DING Biotechnology Co., Ltd.	C3492-5G	2-Chloroquinoxaline	1448-87-9	98.0%(GC)	5G	￥1350.0	2022-07-28
Chemenu	CM121548-100g	2-Chloroquinoxaline	1448-87-9	98%	100g	$295	2021-08-06

2-Chloroquinoxaline Production Method

2-Chloroquinoxaline Suppliers

Suzhou Senfeida Chemical Co., Ltd

Gold Member

Audited Supplier

(CAS:1448-87-9)2-Chloroquinoxaline

Order Number:sfd13614

Stock Status:in Stock

Quantity:200kg

Purity:99.9%

Pricing Information Last Updated:Friday, 19 July 2024 14:36

Price ($):discuss personally

Email:[email protected]

Product Official Link

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Related Categories

Additional information on 2-Chloroquinoxaline

Comprehensive Overview of 2-Chloroquinoxaline (CAS No. 1448-87-9): Properties, Applications, and Industry Insights

2-Chloroquinoxaline (CAS No. 1448-87-9) is a heterocyclic organic compound featuring a quinoxaline backbone substituted with a chlorine atom at the 2-position. This chlorinated quinoxaline derivative is widely recognized for its versatility in pharmaceutical, agrochemical, and material science research. Its molecular formula, C₈H₅ClN₂, and structural uniqueness make it a valuable intermediate for synthesizing complex molecules. Recent trends in drug discovery and crop protection have heightened interest in this compound, as evidenced by rising searches for "2-Chloroquinoxaline uses" and "CAS 1448-87-9 suppliers" across scientific databases.

The compound’s physicochemical properties include a melting point range of 65–68°C and moderate solubility in organic solvents like ethanol and dimethyl sulfoxide (DMSO). These traits facilitate its application in cross-coupling reactions, a hotspot in modern organic chemistry. Researchers increasingly explore "2-Chloroquinoxaline Suzuki coupling" and "palladium-catalyzed reactions" to create novel biaryl structures for anticancer agents or OLED materials. Such applications align with the growing demand for sustainable synthesis methods, a topic dominating 2024’s chemical innovation discussions.

In pharmaceuticals, 2-Chloroquinoxaline serves as a precursor for kinase inhibitors and antibacterial compounds. Its role in developing EGFR inhibitors has gained attention due to the global focus on targeted cancer therapies. Meanwhile, agrochemical studies leverage its scaffold to design pesticide intermediates, addressing challenges like resistance management—a key concern in precision agriculture. Searches for "2-Chloroquinoxaline in crop science" reflect this intersection of chemistry and food security trends.

From a commercial perspective, the compound’s supply chain is influenced by green chemistry regulations and API manufacturing standards. Analytical techniques such as HPLC purity testing and GC-MS characterization ensure compliance with industry benchmarks. Sustainability-driven queries like "eco-friendly synthesis of 1448-87-9" underscore the market’s shift toward environmentally benign processes.

Emerging applications in material science, particularly in conductive polymers and corrosion inhibitors, further expand its relevance. The compound’s electron-deficient quinoxaline core enables n-type semiconductor development, resonating with the renewable energy sector’s needs. This multidisciplinary utility positions 2-Chloroquinoxaline as a compound of enduring significance in both academic and industrial settings.

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