Cas no 1447966-22-4 ([5-(Aminomethyl)thiophen-2-yl](thiophen-3-yl)methanol)

[5-(Aminomethyl)thiophen-2-yl](thiophen-3-yl)methanol is a bifunctional heterocyclic compound featuring both aminomethyl and hydroxymethyl substituents on thiophene rings. Its structure offers versatility as a synthetic intermediate, particularly in pharmaceutical and materials chemistry applications. The presence of reactive functional groups (amine and alcohol) enables selective modifications, facilitating the development of complex molecular architectures. The thiophene scaffolds contribute to electronic properties, making it potentially useful in conjugated systems or as a ligand in coordination chemistry. This compound’s balanced polarity enhances solubility in common organic solvents, simplifying purification and downstream reactions. Its stability under standard conditions ensures reliable handling and storage. Suitable for controlled functionalization, it serves as a valuable building block in medicinal chemistry and polymer research.
[5-(Aminomethyl)thiophen-2-yl](thiophen-3-yl)methanol structure
1447966-22-4 structure
Product Name:[5-(Aminomethyl)thiophen-2-yl](thiophen-3-yl)methanol
CAS No:1447966-22-4
MF:C10H11NOS2
MW:225.330439805984
MDL:MFCD24387833
CID:4775912
PubChem ID:71778095
Update Time:2025-06-08

[5-(Aminomethyl)thiophen-2-yl](thiophen-3-yl)methanol Chemical and Physical Properties

Names and Identifiers

    • [5-(aminomethyl)-2-thienyl](3-thienyl)methanol
    • [5-(aminomethyl)thiophen-2-yl](thiophen-3-yl)methanol
    • [5-(Aminomethyl)thiophen-2-yl](thiophen-3-yl)methanol
    • MDL: MFCD24387833
    • Inchi: 1S/C10H11NOS2/c11-5-8-1-2-9(14-8)10(12)7-3-4-13-6-7/h1-4,6,10,12H,5,11H2
    • InChI Key: GEUUISKLTZNDTJ-UHFFFAOYSA-N
    • SMILES: S1C(CN)=CC=C1C(C1=CSC=C1)O

Computed Properties

  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 4
  • Heavy Atom Count: 14
  • Rotatable Bond Count: 3
  • Complexity: 191
  • XLogP3: 1
  • Topological Polar Surface Area: 103

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Additional information on [5-(Aminomethyl)thiophen-2-yl](thiophen-3-yl)methanol

Comprehensive Overview of [5-(Aminomethyl)thiophen-2-yl](thiophen-3-yl)methanol (CAS No. 1447966-22-4)

[5-(Aminomethyl)thiophen-2-yl](thiophen-3-yl)methanol, with the CAS registry number 1447966-22-4, is a specialized organic compound that has garnered significant attention in pharmaceutical and material science research. This compound features a unique molecular structure combining thiophene rings and an aminomethyl functional group, making it a versatile intermediate for synthesizing advanced materials and bioactive molecules. Its dual thiophene backbone and methanol derivative properties contribute to its potential applications in drug discovery, optoelectronics, and polymer chemistry.

In recent years, the demand for heterocyclic compounds like [5-(Aminomethyl)thiophen-2-yl](thiophen-3-yl)methanol has surged due to their role in developing small-molecule therapeutics and organic semiconductors. Researchers are particularly interested in its structure-activity relationship (SAR), which is critical for designing targeted inhibitors for enzymes or receptors. The compound’s aminomethyl group also allows for further derivatization, enabling the creation of libraries for high-throughput screening (HTS) in drug development.

From an industrial perspective, 1447966-22-4 is often discussed in forums related to green chemistry and sustainable synthesis. With growing environmental concerns, chemists are exploring eco-friendly routes to synthesize such thiophene-based derivatives using catalytic methods or biocatalysis. This aligns with the broader trend of reducing hazardous waste and energy consumption in chemical manufacturing.

The compound’s potential in optoelectronic materials is another hot topic. Thiophene derivatives are known for their electron-rich properties, making them ideal for organic light-emitting diodes (OLEDs), photovoltaic cells, and conductive polymers. [5-(Aminomethyl)thiophen-2-yl](thiophen-3-yl)methanol could serve as a precursor for π-conjugated systems, which are pivotal in advancing flexible electronics and wearable technology.

Frequently asked questions about CAS No. 1447966-22-4 include its solubility, stability under various conditions, and commercial availability. While the compound is typically soluble in polar organic solvents like DMSO or methanol, its stability in aqueous environments requires careful handling. Suppliers often provide it as a high-purity powder, but custom synthesis services are also available for large-scale projects.

In summary, [5-(Aminomethyl)thiophen-2-yl](thiophen-3-yl)methanol (1447966-22-4) is a multifaceted compound with promising applications across pharmaceuticals, materials science, and green chemistry. Its structural features and adaptability position it as a valuable asset for researchers aiming to innovate in these fields. As interest in tailored heterocycles grows, this compound is likely to remain a focal point in both academic and industrial research.

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