• 1. Enantio- & chemo-selective preparation of enantiomerically enriched aliphatic nitro alcohols using Candida parapsilosis ATCC 7330
  Sowmyalakshmi Venkataraman RSC Adv., 2015,5, 73807-73813
• 2. Fe/Fe3C@C nanoparticles encapsulated in N-doped graphene–CNTs framework as an efficient bifunctional oxygen electrocatalyst for robust rechargeable Zn–air batteries?
  Zhiyan Chen,Nan Wu,Yaobing Wang,Bing Wang,Yingde Wang J. Mater. Chem. A, 2018,6, 516-526
• 3. Establishing empirical design rules of nucleic acid templates for the synthesis of silver nanoclusters with tunable photoluminescence and functionalities towards targeted bioimaging applications?
  Jason Y. C. Lim,Yong Yu,Guorui Jin,Kai Li,Yi Lu,Jianping Xie Nanoscale Adv., 2020,2, 3921-3932
• 4. Fatty acid eutectic mixtures and derivatives from non-edible animal fat as phase change materials?
  Pau Gallart-Sirvent,Marc Martín,Gemma Villorbina,Mercè Balcells,Aran Solé,Luisa F. Cabeza,Ramon Canela-Garayoa RSC Adv., 2017,7, 24133-24139
• 5. Fe(iii)-mediated isomerization of α,α-diarylallylic alcohols to ketones via radical 1,2-aryl migration?
  Ziyang Deng,Changwei Chen,Sunliang Cui RSC Adv., 2016,6, 93753-93755

Introduction to 1-Methyl-1H-pyrrolo[2,3-b]pyridin-6-amine (CAS No. 1446791-69-0)

1-Methyl-1H-pyrrolo[2,3-b]pyridin-6-amine, also known by its CAS registry number CAS No. 1446791-69-0, is a structurally unique compound that has garnered significant attention in the fields of organic chemistry and pharmacology. This compound belongs to the class of pyrrolopyridines, which are bicyclic structures combining a pyrrole and a pyridine ring. The presence of the methyl group at the 1-position and the amine group at the 6-position introduces unique electronic and steric properties, making it a promising candidate for various applications.

The synthesis of CAS No. 1446791-69-0 involves a multi-step process that typically begins with the preparation of the pyrrolopyridine core. Recent advancements in synthetic methodologies have enabled chemists to achieve higher yields and better purity levels. For instance, researchers have employed cross-coupling reactions and direct arylation techniques to construct the bicyclic framework efficiently. These methods not only simplify the synthesis but also reduce the environmental footprint compared to traditional approaches.

One of the most intriguing aspects of 1-Methyl-1H-pyrrolo[2,3-b]pyridin-6-amine is its pharmacological activity. Studies have shown that this compound exhibits potent antimicrobial properties, particularly against gram-positive bacteria. This makes it a potential candidate for developing new antibiotics in an era where antibiotic resistance is a growing concern. Furthermore, preliminary tests indicate that it may also possess anti-inflammatory effects, which could be harnessed for treating conditions such as arthritis and other inflammatory disorders.

In addition to its therapeutic potential, CAS No. 1446791-69-0 has shown promise in materials science applications. Its rigid bicyclic structure and conjugated π-system make it an ideal candidate for use in organic electronics. Researchers are exploring its potential as a component in organic light-emitting diodes (OLEDs) and field-effect transistors (FETs) due to its excellent charge transport properties. The methyl group at the 1-position plays a crucial role in modulating these electronic characteristics, further enhancing its versatility.

Recent studies have also delved into the biodegradation pathways of CAS No. 1446791-69-0, shedding light on its environmental impact. Findings suggest that under aerobic conditions, the compound undergoes rapid degradation, minimizing its persistence in natural ecosystems. This is particularly important for industries seeking eco-friendly alternatives for their chemical formulations.

Looking ahead, the development of novel derivatives of CAS No. 1446791-69

• 80235-02-5(1H-Pyrrolo[2,3-b]pyridin-2-amine)
• 158155-73-8(1H-Pyrrolo[2,3-b]pyridine, 6-(7H-pyrrolo[2,3-b]pyridin-7-yl)-)
• 7752-54-7(7-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine)
• 145901-11-7(1H-Pyrrolo[2,3-b]pyridin-6-amine)
• 81965-19-7(1-methyl-1H-Pyrrolo[2,3-d]pyrimidin-4-amine)
• 2098070-20-1(2-(3-(Pyridin-3-yl)-1H-pyrazol-1-yl)acetimidamide)
• 2680771-01-9(4-cyclopentyl-3-{(prop-2-en-1-yloxy)carbonylamino}butanoic acid)
• 1444113-98-7(N-(3-cyanothiolan-3-yl)-2-[(2,2,2-trifluoroethyl)sulfanyl]pyridine-4-carboxamide)
• 332062-08-5(Fmoc-S-3-amino-4,4-diphenyl-butyric acid)
• 1270529-38-8(1,2,3,4,5,6-Hexahydro-[2,3]bipyridinyl-6-ol)