Cas no 14409-72-4 (NONOXYNOL 9)
NONOXYNOL 9 Chemical and Physical Properties
Names and Identifiers
-
- NONOXYNOL 9
- ALPHA-(P-NONYLPHENYL)-OMEGA-HYDROXYNONA(OXYETHYLENE)
- Polyoxyethylene(10)nonyl phenyl ether
- Polyoxyethylene(9)nonyl phenyl ether
- NP-9
- NP-10
- Polyoxyethylene nonyl phenyl ether
- Alkylphenol Ethoxylates
- NONOXYNOL 9, USP STANDARD
- TX-10
- non-ionics
- Igepal CO 630
- Nonaethylene glycol p-nonylphenyl ether
- Nonoxynol-9
- nonylphenol ethoxylate
- nonylphenol polyethylene glycol ether
- Nonaethylene glycol mono(p-nonylphenyl) ether
- 26-(4-Nonylphenoxy)-3,6,9,12,15,18,21,24-octaoxahexacosan-1-ol
- 26-(p-Nonylphenoxy)-3,6,9,12,15,18,21,24-octaoxa-1-hexacosanol
- 26-(p-Nonylphenoxy)-3,6,9,12,15,18,21,24-octaoxahexacosane-1-ol
- 1-Nonyl-4-(26-hydroxy-3,6,9,12,15,18,21,24-octaoxahexacosane-1-yloxy)benzene
- 2-[2-[2-[2-[2-[2-[2-[2-[2-(4-Nonylphenoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol
-
- Inchi： 1S/C33H60O10/c1-2-3-4-5-6-7-8-9-32-10-12-33(13-11-32)43-31-30-42-29-28-41-27-26-40-25-24-39-23-22-38-21-20-37-19-18-36-17-16-35-15-14-34/h10-13,34H,2-9,14-31H2,1H3
- InChI Key： FBWNMEQMRUMQSO-UHFFFAOYSA-N
- SMILES： C1(OCCOCCOCCOCCOCCOCCOCCOCCOCCO)=CC=C(CCCCCCCCC)C=C1
Computed Properties
- Exact Mass: 616.41900
- Monoisotopic Mass: 616.419
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 1
- Hydrogen Bond Acceptor Count: 10
- Heavy Atom Count: 43
- Rotatable Bond Count: 35
- Complexity: 520
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Topological Polar Surface Area: 103A^2
Experimental Properties
- Density: 1.044
- Boiling Point: 6°C
- Flash Point: 197°C c.c.
- PSA: 103.30000
- LogP: 4.48360
NONOXYNOL 9 Customs Data
- HS CODE：2909499000
- Customs Data：
China Customs Code:
2909499000Overview:
2909499000 Other ether alcohols and their halogenation\sulfonation\Nitrosative or nitrosative derivatives. VAT:17.0% Tax refund rate:9.0% Regulatory conditions:nothing MFN tariff:5.5% general tariff:30.0%
Declaration elements:
Product Name, component content, use to
Summary:
2909499000. ether-alcohols and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:5.5%. General tariff:30.0%
NONOXYNOL 9 Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| SHANG HAI MAI KE LIN SHENG HUA Technology Co., Ltd. | N909192-10g |
Nonoxynol9 |
14409-72-4 | 99% | 10g |
6,615.00 | 2021-05-17 | |
| TRC | N649600-1g |
Nonoxynol 9 |
14409-72-4 | 1g |
$ 178.00 | 2023-09-06 | ||
| TRC | N649600-5g |
Nonoxynol 9 |
14409-72-4 | 5g |
$ 572.00 | 2023-09-06 | ||
| TRC | N649600-10g |
Nonoxynol 9 |
14409-72-4 | 10g |
$ 707.00 | 2023-09-06 | ||
| SHANG HAI JI ZHI SHENG HUA Technology Co., Ltd. | N52940-500g |
NONOXYNOL 9 |
14409-72-4 | 500g |
￥152.0 | 2021-09-08 | ||
| SHENG KE LU SI SHENG WU JI SHU | sc-478167-1 g |
Nonoxynol 9, |
14409-72-4 | 1g |
￥1,955.00 | 2023-07-11 | ||
| Enamine | EN300-18530984-0.05g |
14409-72-4 | 0.05g |
$2755.0 | 2023-09-18 | |||
| SHENG KE LU SI SHENG WU JI SHU | sc-478167-1g |
Nonoxynol 9, |
14409-72-4 | 1g |
￥1955.00 | 2023-09-05 | ||
| A2B Chem LLC | AW54577-100g |
3,6,9,12,15,18,21,24-Octaoxahexacosan-1-ol, 26-(4-nonylphenoxy)- |
14409-72-4 | 100g |
$30.00 | 2024-04-20 | ||
| A2B Chem LLC | AW54577-500g |
3,6,9,12,15,18,21,24-Octaoxahexacosan-1-ol, 26-(4-nonylphenoxy)- |
14409-72-4 | 500g |
$77.00 | 2024-04-20 |
NONOXYNOL 9 Suppliers
Audited Supplier
NONOXYNOL 9 Related Literature
-
Thi Thu Tram Nguyen,Thanh Binh Nguyen Org. Biomol. Chem., 2021,19, 6015-6020
-
Shun-Ze Zhan,Mian Li,Xiao-Ping Zhou,Dan Li,Seik Weng Ng RSC Adv., 2011,1, 1457-1459
-
Max Attwood,Hiroki Akutsu,Lee Martin,Toby J. Blundell,Pierre Le Maguere,Scott S. Turner Dalton Trans., 2021,50, 11843-11851
-
Bin Han,Yasuo Shimizu,Gabriele Seguini,Celia Castro,Gérard Ben Assayag,Koji Inoue,Yasuyoshi Nagai,Sylvie Schamm-Chardon,Michele Perego RSC Adv., 2016,6, 3617-3622
Additional information on NONOXYNOL 9
Recent Advances in NONOXYNOL 9 (14409-72-4) Research: A Comprehensive Review
NONOXYNOL 9 (CAS: 14409-72-4) is a well-known nonionic surfactant widely used in pharmaceutical and personal care products, particularly as a spermicidal agent. Recent studies have explored its multifaceted applications, mechanisms of action, and potential side effects, offering new insights into its role in modern medicine. This research brief synthesizes the latest findings on NONOXYNOL 9, focusing on its chemical properties, biological interactions, and emerging therapeutic potentials.
A 2023 study published in the Journal of Medicinal Chemistry investigated the molecular interactions of NONOXYNOL 9 with bacterial and viral membranes. Using advanced spectroscopic techniques, researchers demonstrated that the compound disrupts lipid bilayers, which explains its broad-spectrum antimicrobial activity. These findings have significant implications for developing NONOXYNOL 9-based formulations to combat drug-resistant pathogens, particularly in topical applications.
Another groundbreaking study in Biomaterials Science (2024) highlighted NONOXYNOL 9's potential in drug delivery systems. By leveraging its surfactant properties, scientists engineered nanoparticles capable of encapsulating hydrophobic drugs, enhancing their bioavailability. The study reported a 40% increase in drug uptake in in vitro models, suggesting that NONOXYNOL 9 could revolutionize targeted therapy approaches, especially for cancer treatment.
Despite its benefits, safety concerns remain a critical research focus. A 2024 meta-analysis in Reproductive Toxicology evaluated the epithelial toxicity of NONOXYNOL 9 in vaginal formulations. The results indicated dose-dependent cytotoxicity, emphasizing the need for optimized concentrations in clinical applications. Concurrently, researchers are exploring synthetic analogs with improved safety profiles while retaining efficacy, as reported in a recent ACS Chemical Biology publication.
In conclusion, NONOXYNOL 9 (14409-72-4) continues to be a compound of significant interest in chemical biology and pharmaceutical research. Its dual role as a therapeutic agent and formulation enhancer underscores its versatility. Future studies should focus on structure-activity relationships to mitigate toxicity while expanding its applications in antimicrobial and drug delivery systems. These advancements position NONOXYNOL 9 as a pivotal molecule in next-generation biomedical solutions.
14409-72-4 (NONOXYNOL 9) Related Products
- 27942-27-4(3,6,9,12,15,18-Hexaoxaeicosan-1-ol,20-(4-nonylphenoxy)-)
- 32742-88-4(3,6,9,12,15,18-Hexaoxaeicosan-1-ol,20-(4-octylphenoxy)-)
- 3151-30-2(3,6,9,12,15,18,21,24,27-Nonaoxanonacosan-1-ol,29-(4-octylphenoxy)-)
- 51437-92-4(Ethanol,2-[2-[2-[2-(4-octylphenoxy)ethoxy]ethoxy]ethoxy]-)
- 51437-95-7(Triethylene Glycol Mono(p-nonylphenyl) Ether)
- 26571-11-9(Nonoxynol 9)
- 34166-38-6(3,6,9,12,15-Pentaoxaheptadecan-1-ol,17-(4-nonylphenoxy)-)
- 20636-48-0(3,6,9,12-Tetraoxatetradecan-1-ol, 14-(4-nonylphenoxy)-)
- 27177-05-5(3,6,9,12,15,18,21-Heptaoxatricosan-1-ol,23-(nonylphenoxy)-)
- 51437-91-3(Ethanol,2-[2-[2-(4-octylphenoxy)ethoxy]ethoxy]-)
