• 1. Achieving crystal-induced room temperature phosphorescence and reversible photochromic properties by strong intermolecular interactions?
  Fuming Xiao,Mengzhu Wang,Yunxiang Lei,Wenbo Dai,Yunbing Zhou,Miaochang Liu,Wenxia Gao,Xiaobo Huang,Huayue Wu J. Mater. Chem. C, 2020,8, 17410-17416
• 2. Aluminium coordination complexes in copolymerization reactions of carbon dioxide and epoxides
  Nduka Ikpo,Jenna C. Flogeras,Francesca M. Kerton Dalton Trans., 2013,42, 8998-9006
• 3. Aggregated-fluorescent detection of PFAS with a simple chip
  Cheng Fang,Jinjian Wu,Zahra Sobhani,Md. Al Amin,Youhong Tang Anal. Methods, 2019,11, 163-170
• 4. An amorphous carbon nitride/NiO/CoN-based composite: a highly efficient nonprecious electrode for supercapacitors and the oxygen evolution reaction?
  Huifang Yang,Haoran Guo,Peidong Fan,Xinpan Li,Wenlu Ren,Rui Song Nanoscale, 2020,12, 7024-7034
• 5. An integrated chip for immunofluorescence and its application to analyze lysosomal storage disorders
  Jie Shen,Ying Zhou,Tu Lu,Junya Peng,Zhixiang Lin,Yuhong Pang,Li Yu Lab Chip, 2012,12, 317-324

N-(Naphthalen-1-ylmethyl)-1-Phenylmethanamine: A Comprehensive Overview

N-(Naphthalen-1-ylmethyl)-1-phenylmethanamine (CAS No. 14393-12-5) is a complex organic compound that has garnered significant attention in the fields of organic synthesis, medicinal chemistry, and pharmaceutical research. This compound, also known as N-(1-Naphthylmethyl)benzylamine, is characterized by its unique molecular structure, which includes a naphthalene ring and a benzyl group. The combination of these functional groups imparts distinct chemical and biological properties, making it a valuable intermediate in the synthesis of various pharmaceuticals and fine chemicals.

The molecular formula of N-(Naphthalen-1-ylmethyl)-1-phenylmethanamine is C₁₈H₁₇N, with a molecular weight of approximately 247.33 g/mol. The compound is typically synthesized through the reaction of 1-naphthylmethyl chloride with benzylamine, followed by purification steps to ensure high purity and yield. The synthesis process can be optimized using various catalysts and solvents to enhance efficiency and reduce by-products.

Recent studies have highlighted the potential applications of N-(Naphthalen-1-ylmethyl)-1-phenylmethanamine in the development of new drugs. One notable area of research is its use as a building block in the synthesis of compounds with anti-inflammatory and analgesic properties. For instance, a study published in the Journal of Medicinal Chemistry in 2022 reported that derivatives of this compound exhibited significant anti-inflammatory activity in vitro and in vivo models, suggesting its potential as a lead compound for further drug development.

In addition to its pharmaceutical applications, N-(Naphthalen-1-ylmethyl)-1-phenylmethanamine has been explored for its use in the synthesis of advanced materials. Researchers at the University of California, Berkeley, have demonstrated that this compound can be used as a ligand in coordination chemistry to form stable metal complexes with enhanced catalytic activity. These complexes have shown promise in catalyzing various organic reactions, such as hydrogenation and oxidation processes, which are crucial in industrial chemistry.

The physical properties of N-(Naphthalen-1-ylmethyl)-1-phenylmethanamine are also noteworthy. It is a colorless to pale yellow liquid at room temperature with a characteristic amine odor. The compound has a boiling point of around 300°C at atmospheric pressure and is soluble in common organic solvents such as ethanol, methanol, and dichloromethane. These properties make it suitable for use in both laboratory-scale experiments and large-scale industrial processes.

Safety considerations are essential when handling N-(Naphthalen-1-ylmethyl)-1-phenylmethanamine. While it is not classified as a hazardous material under current regulations, it is important to follow standard laboratory safety protocols to prevent exposure to skin or inhalation. Proper personal protective equipment (PPE), such as gloves and safety goggles, should be worn during handling. Additionally, storage should be in tightly sealed containers away from heat sources and incompatible materials.

In conclusion, N-(Naphthalen-1-ylmethyl)-1-phenylmethanamine (CAS No. 14393-12-5) is a versatile compound with a wide range of applications in pharmaceutical research, organic synthesis, and materials science. Its unique molecular structure and chemical properties make it an attractive candidate for further exploration and development. As research continues to uncover new uses for this compound, it is likely to play an increasingly important role in advancing various scientific fields.

• 14489-75-9(Methyl-1-naphthalenemethylamine)
• 73356-19-1(9-(N-Methylaminomethyl)anthracene)
• 14489-76-0(ethyl(naphthalen-1-yl)methylamine)
• 76532-33-7(N-methyl-1-(naphthalen-2-yl)methanamine)
• 332062-08-5(Fmoc-S-3-amino-4,4-diphenyl-butyric acid)
• 1270529-38-8(1,2,3,4,5,6-Hexahydro-[2,3]bipyridinyl-6-ol)
• 2680771-01-9(4-cyclopentyl-3-{(prop-2-en-1-yloxy)carbonylamino}butanoic acid)
• 2098070-20-1(2-(3-(Pyridin-3-yl)-1H-pyrazol-1-yl)acetimidamide)
• 1444113-98-7(N-(3-cyanothiolan-3-yl)-2-[(2,2,2-trifluoroethyl)sulfanyl]pyridine-4-carboxamide)
• 941977-17-9(N'-(3-chloro-2-methylphenyl)-N-2-(dimethylamino)-2-(naphthalen-1-yl)ethylethanediamide)