Cas no 1432030-30-2 (4-chloro-1-ethyl-1H-pyrazol-3-amine hydrochloride)

4-Chloro-1-ethyl-1H-pyrazol-3-amine hydrochloride is a heterocyclic organic compound featuring a pyrazole core substituted with chloro and ethyl groups, along with an amine functionality. The hydrochloride salt form enhances its stability and solubility, making it suitable for synthetic applications in pharmaceutical and agrochemical research. Its reactive amine group allows for further functionalization, enabling the synthesis of diverse derivatives. The chloro substituent provides a handle for cross-coupling reactions, expanding its utility in medicinal chemistry. This compound is particularly valuable as a building block for developing biologically active molecules, offering a balance of reactivity and selectivity. Proper handling and storage under anhydrous conditions are recommended to maintain its integrity.
4-chloro-1-ethyl-1H-pyrazol-3-amine hydrochloride structure
1432030-30-2 structure
Product Name:4-chloro-1-ethyl-1H-pyrazol-3-amine hydrochloride
CAS No:1432030-30-2
MF:C5H9Cl2N3
MW:182.051058530807
MDL:MFCD25971860
CID:4599411
Update Time:2025-10-23

4-chloro-1-ethyl-1H-pyrazol-3-amine hydrochloride Chemical and Physical Properties

Names and Identifiers

    • 4-chloro-1-ethyl-1H-pyrazol-3-amine hydrochloride
    • AT16075
    • 4-chloro-1-ethylpyrazol-3-amine;hydrochloride
    • 4-CHLORO-1-ETHYL-1H-PYRAZOL-3-AMINE HCL
    • MDL: MFCD25971860
    • Inchi: 1S/C5H8ClN3.ClH/c1-2-9-3-4(6)5(7)8-9;/h3H,2H2,1H3,(H2,7,8);1H
    • InChI Key: IKEYDHUGDFYFER-UHFFFAOYSA-N
    • SMILES: ClC1C(N)=NN(C=1)CC.Cl

Computed Properties

  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 10
  • Rotatable Bond Count: 1
  • Complexity: 98.2
  • Topological Polar Surface Area: 43.8

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Additional information on 4-chloro-1-ethyl-1H-pyrazol-3-amine hydrochloride

Comprehensive Overview of 4-chloro-1-ethyl-1H-pyrazol-3-amine hydrochloride (CAS No. 1432030-30-2)

4-chloro-1-ethyl-1H-pyrazol-3-amine hydrochloride (CAS No. 1432030-30-2) is a specialized organic compound that has garnered significant attention in pharmaceutical and agrochemical research. This compound, often referred to by its systematic name, belongs to the pyrazole derivative family, which is known for its versatile applications in medicinal chemistry and material science. Researchers and industry professionals frequently search for terms like "pyrazole derivatives synthesis", "amine hydrochloride applications", and "chloro-substituted pyrazoles", reflecting the growing interest in this chemical class.

The molecular structure of 4-chloro-1-ethyl-1H-pyrazol-3-amine hydrochloride features a chloro-substituted pyrazole ring, an ethyl group at the N1 position, and an amine functional group at the C3 position, which is protonated as a hydrochloride salt. This unique combination of substituents makes it a valuable intermediate in the synthesis of more complex molecules. Recent trends in scientific literature highlight the importance of "heterocyclic compound optimization" and "salt formation in drug development", topics closely related to this compound's properties.

In the context of current research hotspots, 4-chloro-1-ethyl-1H-pyrazol-3-amine hydrochloride aligns with several cutting-edge themes. For instance, the rise of "fragment-based drug design" has increased demand for small, well-characterized building blocks like this pyrazole derivative. Additionally, the compound's potential role in "crop protection agent development" makes it relevant to sustainable agriculture discussions, a topic frequently searched in academic and industrial circles.

The physicochemical properties of CAS No. 1432030-30-2 contribute to its utility in various applications. Its moderate solubility in polar solvents and stability under standard conditions make it suitable for diverse synthetic transformations. Recent publications have explored its use in "multi-component reactions" and as a precursor for "biologically active scaffolds", addressing common queries in chemical synthesis forums.

Quality control and analytical characterization of 4-chloro-1-ethyl-1H-pyrazol-3-amine hydrochloride typically involve techniques such as HPLC, NMR spectroscopy, and mass spectrometry. These methods ensure the compound meets the stringent purity requirements for research applications. The growing emphasis on "analytical method validation" and "impurity profiling" in regulatory guidelines has made proper characterization of such intermediates increasingly important.

From a commercial perspective, the availability of CAS 1432030-30-2 through specialty chemical suppliers has facilitated its adoption in various research programs. The compound's shelf life, storage conditions, and handling precautions are frequently searched topics, reflecting practical concerns among end-users. Proper documentation of these parameters is essential for maintaining compound integrity throughout the supply chain.

Looking forward, the applications of 4-chloro-1-ethyl-1H-pyrazol-3-amine hydrochloride may expand into emerging areas such as "catalysis" and "materials science". Its structural features make it a candidate for developing novel ligands or functional materials, aligning with current interests in "molecular engineering" and "smart material design". These potential applications address frequently asked questions about the future directions of heterocyclic chemistry.

In summary, 4-chloro-1-ethyl-1H-pyrazol-3-amine hydrochloride represents an important building block in modern chemical research. Its well-defined structure, synthetic versatility, and relevance to current scientific trends make it a compound of continuing interest. As research into "structure-activity relationships" and "molecular diversity" progresses, the significance of such carefully designed intermediates is likely to grow further.

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