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• Solvents and Organic Chemicals Organic Compounds Organic nitrogen compounds Organonitrogen compounds Amines Primary amines

Comprehensive Guide to 2-(1-methyl-1H-pyrazol-4-yl)ethanamine (CAS No. 1431962-30-9): Properties, Applications, and Market Insights

The compound 2-(1-methyl-1H-pyrazol-4-yl)ethanamine (CAS No. 1431962-30-9) is a specialized pyrazole derivative with growing significance in pharmaceutical and agrochemical research. This amine-functionalized pyrazole exhibits unique structural features that make it valuable for drug discovery and material science applications. Its molecular formula, C6H11N3, and molecular weight of 125.17 g/mol position it as a versatile building block in organic synthesis.

Recent trends in heterocyclic compound research have highlighted the importance of pyrazole-based amines like 2-(1-methyl-1H-pyrazol-4-yl)ethanamine due to their diverse biological activities. The compound's structure combines a methyl-substituted pyrazole core with an ethylamine side chain, creating opportunities for hydrogen bonding and molecular interactions that are particularly valuable in medicinal chemistry. Researchers frequently search for "pyrazole amine derivatives" and "CAS 1431962-30-9 applications" when investigating similar compounds.

The physical properties of 2-(1-methyl-1H-pyrazol-4-yl)ethanamine contribute to its utility in various applications. Typically appearing as a white to off-white crystalline powder, this compound shows good solubility in common organic solvents such as methanol, ethanol, and dimethyl sulfoxide (DMSO). Its melting point range of 80-85°C and moderate stability under standard conditions make it suitable for laboratory handling and industrial-scale processes. The "1-methyl-1H-pyrazol-4-yl" moiety provides excellent chemical stability while the ethanamine group offers reactivity for further derivatization.

In pharmaceutical applications, 2-(1-methyl-1H-pyrazol-4-yl)ethanamine serves as a key intermediate for developing potential therapeutic agents. Recent patent literature reveals its use in creating kinase inhibitors, particularly for cancer treatment research. The compound's ability to form stable complexes with various biological targets has led to increased interest from medicinal chemists searching for "pyrazole-based drug candidates". Its structural similarity to known bioactive molecules makes it particularly valuable for fragment-based drug design approaches.

The agrochemical industry has also recognized the potential of 2-(1-methyl-1H-pyrazol-4-yl)ethanamine derivatives. As researchers seek more environmentally friendly crop protection solutions, this compound's framework has shown promise in developing new classes of plant growth regulators and pest control agents. The "methyl pyrazole ethanamine" structure appears in several recent studies investigating novel modes of action for agricultural chemicals, addressing growing concerns about resistance development in pest populations.

Synthetic approaches to 2-(1-methyl-1H-pyrazol-4-yl)ethanamine typically involve multi-step organic transformations. Common routes begin with 1-methyl-1H-pyrazole-4-carbaldehyde, proceeding through reductive amination or other amine-forming reactions. Recent advancements in green chemistry methodologies have improved the sustainability of these synthetic pathways, reducing waste generation and energy consumption. These developments align with current industry trends toward more sustainable chemical production, a topic frequently searched as "green synthesis of heterocycles".

The global market for pyrazole derivatives like 2-(1-methyl-1H-pyrazol-4-yl)ethanamine has shown steady growth, driven by increasing demand from pharmaceutical and agricultural sectors. Market analysts project compound annual growth rates of 5-7% for similar specialty chemicals through 2028. Suppliers and researchers often search for "CAS 1431962-30-9 suppliers" and "high purity pyrazole amines" when sourcing this material, indicating strong commercial interest.

Quality control and analytical characterization of 2-(1-methyl-1H-pyrazol-4-yl)ethanamine typically involve HPLC, GC-MS, and NMR techniques. The compound's purity is crucial for research applications, with most commercial samples available at ≥95% purity. Advanced users frequently search for "analytical methods for pyrazole amines" and "spectral data of 1431962-30-9" when working with this material, highlighting the need for reliable characterization data.

Storage and handling recommendations for 2-(1-methyl-1H-pyrazol-4-yl)ethanamine include protection from moisture and oxidation. Standard practice suggests storage in tightly sealed containers under inert atmosphere at temperatures below 25°C. These precautions maintain the compound's stability and shelf life, important considerations for researchers investigating "long-term stability of amine compounds" and "proper storage of heterocyclic amines".

Future research directions for 2-(1-methyl-1H-pyrazol-4-yl)ethanamine include exploration of its coordination chemistry with transition metals and development of novel polymeric materials incorporating its structure. The compound's dual functionality makes it attractive for creating metal-organic frameworks (MOFs) and other advanced materials. These applications align with growing interest in "functional organic building blocks" and "pyrazole-containing materials" within the materials science community.

In conclusion, 2-(1-methyl-1H-pyrazol-4-yl)ethanamine (CAS No. 1431962-30-9) represents a versatile and valuable compound with wide-ranging applications in pharmaceutical, agrochemical, and materials science research. Its unique structural features and growing commercial availability ensure continued interest from researchers and industry professionals searching for "specialty pyrazole derivatives" and "multifunctional heterocyclic amines". As synthetic methodologies advance and new applications emerge, this compound is poised to play an increasingly important role in scientific innovation.

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