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3-Amino-N-(4-methylphenyl)benzamide (CAS No. 14315-26-5): A Comprehensive Overview

3-Amino-N-(4-methylphenyl)benzamide, also known by its CAS registry number 14315-26-5, is a chemical compound that has garnered significant attention in various fields of research, particularly in pharmaceuticals and materials science. This compound is characterized by its unique structure, which combines an amino group with a benzamide moiety, making it a versatile molecule with potential applications in drug design and advanced materials. In this article, we will delve into the properties, synthesis, applications, and recent advancements related to 3-Amino-N-(4-methylphenyl)benzamide.

The molecular structure of 3-Amino-N-(4-methylphenyl)benzamide consists of a benzene ring substituted with an amino group at the 3-position and an N-(4-methylphenyl) group attached to the carbonyl carbon of the benzamide. This configuration imparts the compound with unique electronic and steric properties, which are crucial for its functional applications. Recent studies have highlighted the importance of such structural features in enhancing the bioavailability and efficacy of drugs derived from this compound.

From a chemical standpoint, 3-Amino-N-(4-methylphenyl)benzamide exhibits interesting reactivity due to the presence of both electron-donating and electron-withdrawing groups. The amino group acts as an electron donor, while the carbonyl group serves as an electron acceptor, creating a conjugated system that influences the compound's optical and electronic properties. This makes it a valuable component in the synthesis of advanced materials such as organic semiconductors and optoelectronic devices.

The synthesis of 3-Amino-N-(4-methylphenyl)benzamide typically involves multi-step organic reactions, including nucleophilic acyl substitution and amide bond formation. Recent advancements in catalytic methods have enabled more efficient and environmentally friendly syntheses of this compound. For instance, researchers have explored the use of transition metal catalysts to facilitate the coupling reactions involved in its preparation, significantly improving yield and purity.

In terms of applications, 3-Amino-N-(4-methylphenyl)benzamide has shown promise in the pharmaceutical industry as a potential lead compound for drug development. Its ability to interact with biological targets such as enzymes and receptors makes it a valuable tool in medicinal chemistry. For example, studies have demonstrated its potential as an inhibitor of certain kinase enzymes, which are implicated in various diseases including cancer.

Beyond pharmaceuticals, this compound has also found applications in materials science. Its unique electronic properties make it suitable for use in organic electronics, where it can serve as a building block for semiconducting materials or light-emitting diodes (LEDs). Recent research has focused on optimizing its performance in these contexts by modifying its structure or incorporating it into polymer frameworks.

One area that has seen significant progress is the study of the toxicological profile of 3-Amino-N-(4-methylphenyl)benzamide. Understanding its safety profile is crucial for its application in drug development and other fields. Recent studies have employed advanced analytical techniques to assess its acute and chronic toxicity, providing valuable insights into its safe handling and use.

In conclusion, 3-Amino-N-(4-methylphenyl)benzamide (CAS No. 14315-26-5) is a multifaceted compound with diverse applications across various scientific domains. Its unique chemical structure and functional properties continue to drive innovative research aimed at unlocking its full potential. As advancements in synthetic methods and material science progress, this compound is poised to play an increasingly important role in both academic research and industrial applications.

• 25050-22-0(Benzamide, N-(3,5-dimethylphenyl)-)
• 14315-16-3(3-Amino-N-phenylbenzamide)
• 5249-42-3(L-Glutamic acid, N-formyl-, 5-(phenylmethyl) ester)
• 14315-23-2(3-Amino-N-(3-methylphenyl)benzamide)
• 2362-24-5(Benzamide, N,N'-1,4-phenylenebis[3-amino-)
• 102630-90-0(3-Amino-N-(3,5-dimethylphenyl)benzamide)
• 2657-93-4(3,4'-Diamino Benzanilide)
• 600124-48-9( )
• 293323-73-6(1,3-Benzenedicarboxamide, N,N'-bis(3-methylphenyl)-)
• 97042-52-9(4-Amino-N-(3,5-dimethylphenyl)benzamide)