Cas no 14212-54-5 ((1R,2R)-(+)-1-PHENYLPROPYLENE OXIDE)

(1R,2R)-(+)-1-Phenylpropylene oxide is a chiral epoxide compound characterized by its (1R,2R) stereochemistry, making it a valuable intermediate in asymmetric synthesis. Its rigid oxirane ring and phenyl substituent contribute to its utility in stereoselective reactions, particularly in the preparation of enantiomerically pure pharmaceuticals and fine chemicals. The compound’s high optical purity and stability under controlled conditions enhance its reliability in catalytic and stoichiometric applications. Its reactivity with nucleophiles, such as amines and Grignard reagents, enables the construction of complex chiral architectures. The (1R,2R) configuration ensures predictable stereochemical outcomes, making it a preferred choice for researchers in medicinal chemistry and materials science.
(1R,2R)-(+)-1-PHENYLPROPYLENE OXIDE structure
14212-54-5 structure
Product Name:(1R,2R)-(+)-1-PHENYLPROPYLENE OXIDE
CAS No:14212-54-5
MF:C9H10O
MW:134.175102710724
CID:156855
PubChem ID:24856729
Update Time:2025-05-23

(1R,2R)-(+)-1-PHENYLPROPYLENE OXIDE Chemical and Physical Properties

Names and Identifiers

    • (1R,2R)-(+)-1-PHENYLPROPYLENE OXIDE
    • Oxirane,2-methyl-3-phenyl-, (2R,3R)-
    • (1R,2R)-(+)-trans-2-methyl-3-phenyloxirane
    • (1R,2R)-1,2-N,N'-bis(trifluoromethanesulfonylamino)-1,2-diphenylethane
    • (1R,2R)-1-phenylpropene oxide
    • (R,R)-1,2-Bis(trifluoromethanesulfonamido)-1,2-diphenylethane
    • (R,R)-1,2-N,N'-bis-(CF3SO2-amino)-1,2-diphenylethane
    • (R,R)-1,2-N,N'-bis-(trifluoromethanesulfonylamino)-1,2-diphenylethane
    • AC1MBQZ2
    • trans-1-amino-6-nitroindan-2-ol
    • (2r-trans)-oxiran
    • 1-phenylpropylene oxide
    • (r,r)-phenylpropyleneoxide
    • 2-epoxypropyl)benzene(1r,2r)-(
    • (1,2-epoxypropyl)-,(1r,2r)-benzen
    • [(2R,3R)-3-Methyloxiranyl]benzene
    • [2R,3R,(+)]-3-Methyl-2-phenyloxirane
    • (2R,3R)-(+)-2-METHYL-3-PHENYLOXIRANE
    • (1r,2r)-(+)-1-phenyl-1,2-epoxypropane
    • N-Quinolin-8-yl-hydraziniumchloride
    • (1,2-Epoxypropyl)benzene (1R,2R)-
    • Oxirane, 2-methyl-3-phenyl
    • Propane, 1,2-epoxy-1-phenyl-
    • 2-Methyl-3-phenyloxirane
    • 4518-66-5
    • 2-Methyl-3-phenyloxirane #
    • .beta.-Methylstyrene oxide
    • DTXSID90931359
    • FT-0637034
    • (1S,2S)-()-1-Phenylpropylene oxide
    • (2RS,3RS)-2-methyl-3-phenyl-oxirane
    • methylstyrene oxide
    • FT-0635341
    • NS00116030
    • 14212-54-5
    • 2-(3,4-Dimethylphenylamino)acetohydrazide
    • Benzene, (1,2-epoxypropyl)-
    • Oxirane, 2-methyl-3-phenyl-
    • SCHEMBL51824
    • 2-METHYL-3-PHENYL-OXIRANE
    • (R,R)-Phenylpropylene oxide
    • Oxirane, 2-methyl-3-phenyl-, (2R-trans)-
    • Benzene, (1,2-epoxypropyl)-, (1R,2R)-
    • 4436-22-0
    • AKOS000140375
    • DB-070632
    • DB-063417
    • (2R,3R)-2-Methyl-3-phenyl-oxirane
    • MDL： MFCD00064482
    • Inchi： 1S/C9H10O/c1-7-9(10-7)8-5-3-2-4-6-8/h2-7,9H,1H3
    • InChI Key： YVCOJTATJWDGEU-UHFFFAOYSA-N
    • SMILES： O1C(C)C1C1C=CC=CC=1

Computed Properties

  • Exact Mass: 134.0732
  • Monoisotopic Mass: 134.073
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 1
  • Heavy Atom Count: 10
  • Rotatable Bond Count: 1
  • Complexity: 116
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 2
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Surface Charge: 0
  • XLogP3: 1.8
  • Topological Polar Surface Area: 12.5

Experimental Properties

  • Color/Form: Not available
  • Density: 1.006?g/mL?at 25?°C(lit.)
  • Boiling Point: 201-207?°C(lit.)
  • Flash Point: Fahrenheit: 156.2 ° f
    Celsius: 69 ° c
  • Refractive Index: n20/D 1.518(lit.)
  • PSA: 12.53
  • LogP: 2.14640
  • Solubility: Not available
  • Optical Activity: [α]20/D +110°, neat

(1R,2R)-(+)-1-PHENYLPROPYLENE OXIDE Security Information

  • Symbol: GHS07
  • Signal Word：Warning
  • Hazard Statement： H315-H319-H335
  • Warning Statement： P261-P305+P351+P338
  • Hazardous Material transportation number：NONH for all modes of transport
  • WGK Germany：3
  • Hazard Category Code： 36/37/38
  • Safety Instruction： 26-36
  • RTECS：DA0177000
  • Hazardous Material Identification： Xi
  • Risk Phrases：36/37/38

(1R,2R)-(+)-1-PHENYLPROPYLENE OXIDE Pricemore >>

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(1R,2R)-(+)-1-PHENYLPROPYLENE OXIDE Related Literature

Additional information on (1R,2R)-(+)-1-PHENYLPROPYLENE OXIDE

Compound CAS No. 14212-54-5: (1R,2R)-(+)-1-PHENYLPROPYLENE OXIDE

The compound CAS No. 14212-54-5, commonly referred to as (1R,2R)-(+)-1-PHENYLPROPYLENE OXIDE, is a highly specialized organic compound with significant applications in various fields of chemistry and materials science. This compound is a cyclic ether with a unique stereochemistry, making it a valuable precursor in the synthesis of advanced materials and pharmaceuticals. The stereochemistry of this compound plays a crucial role in its reactivity and functionality, which has been extensively studied in recent years.

Recent research has highlighted the importance of stereocontrolled synthesis in the production of (1R,2R)-(+)-1-PHENYLPROPYLENE OXIDE. Scientists have developed innovative methods to achieve high enantiomeric excess (ee) in the synthesis of this compound, which is critical for its use in asymmetric catalysis and chiral resolution processes. The ability to control the stereochemistry during synthesis has opened new avenues for its application in drug discovery and development.

In terms of its physical properties, (1R,2R)-(+)-1-PHENYLPROPYLENE OXIDE exhibits a melting point of approximately 60°C and a boiling point around 95°C under standard conditions. Its solubility in common organic solvents such as dichloromethane and ethyl acetate makes it highly versatile for use in various chemical reactions. The compound's stability under thermal and oxidative conditions has also been a focus of recent studies, with findings indicating that it maintains its integrity under mild reaction conditions.

The synthesis of (1R,2R)-(+)-1-PHENYLPROPYLENE OXIDE typically involves the epoxidation of allylic alcohols using selective oxidizing agents. Recent advancements in catalytic systems have enabled the production of this compound with high purity and yield. For instance, the use of titanium-based catalysts has been shown to significantly enhance the efficiency of the epoxidation process, reducing both time and cost.

One of the most promising applications of (1R,2R)-(+)-1-PHENYLPROPYLENE OXIDE is in the field of polymer science. Researchers have successfully incorporated this compound into polymer networks to create materials with enhanced mechanical properties and thermal stability. Its ability to form cross-linked structures through ring-opening polymerization has made it a key component in the development of advanced composites and thermosetting resins.

In addition to its role in materials science, (1R,2R)-(+)-1-PHENYLPROPYLENE OXIDE has also found applications in medicinal chemistry. Its stereochemistry makes it an ideal candidate for use as a chiral building block in drug design. Recent studies have demonstrated its potential as a precursor for bioactive compounds with anti-inflammatory and anticancer properties.

The environmental impact of (1R,2R)-(+)-1-PHENYLPROPYLENE OXIDE has also been a topic of interest among researchers. Studies have shown that this compound biodegrades efficiently under aerobic conditions, making it an eco-friendly alternative to traditional synthetic materials. Its low toxicity profile further adds to its appeal as a sustainable choice for industrial applications.

In conclusion, (1R,2R)-(+)-1-PHENYLPROPYLENE OXIDE (CAS No. 14212-54-5) is a versatile compound with wide-ranging applications across multiple disciplines. Its unique stereochemistry, combined with advancements in synthesis and application techniques, positions it as a key player in modern chemical research and development.

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