• 1. Molecular design of AEC tri-block anionic surfactant towards rational synthesis of targeted thick-walled mesoporous silica
  Runhuan Gong,Lu Han,Chuanbo Gao,Mouhai Shu,Shunai Che J. Mater. Chem. 2009 19 3404
• 2. Structure and rheology of polyelectrolyte complex coacervates
  Amanda B. Marciel,Samanvaya Srivastava,Matthew V. Tirrell Soft Matter 2018 14 2454
• 3. Hydration and dynamics of l-glutamate ion in aqueous solution
  Sergej Friesen,Marina V. Fedotova,Sergey E. Kruchinin,Richard Buchner Phys. Chem. Chem. Phys. 2021 23 1590
• 4. Avidin-adsorbed peptide–calcium phosphate composites exhibiting high biotin-binding activity
  Suzuka Kojima,Fukue Nagata,Masahiko Inagaki,Shinichi Kugimiya,Katsuya Kato New J. Chem. 2019 43 427
• 5. Nano-rods of doxorubicin with poly(l-glutamic acid) as a carrier-free formulation for intratumoral cancer treatment
  Saina Yang,Feiyan Zhu,Qian Wang,Fuxin Liang,Xiaozhong Qu,Zhihua Gan,Zhenzhong Yang J. Mater. Chem. B 2016 4 7283

• Solvents and Organic Chemicals Organic Compounds Organic acids and derivatives Carboxylic acids and derivatives Amino acids, peptides, and analogues Amino acids and derivatives
• Pharmaceutical and Biochemical Products Pharmaceutical Active Ingredients Standard Substances
• Solvents and Organic Chemicals Organic Compounds Acids/Esters
• Pharmaceutical and Biochemical Products Pharmaceutical Active Ingredients

The Chemical Profile and Applications of L-Glutamic acid monosodium salt (CAS No. 142-47-2)

L-Glutamic acid monosodium salt, with the chemical formula C?H?NO?·Na, is a widely recognized compound in the field of pharmaceuticals, food additives, and biochemical research. Its CAS number, 142-47-2, serves as a unique identifier in chemical databases, facilitating precise referencing in scientific literature and industrial applications. This compound is the sodium salt form of L-glutamic acid, an essential amino acid involved in numerous physiological processes.

The significance of L-Glutamic acid monosodium salt lies in its multifaceted roles across different industries. In pharmaceuticals, it is utilized as an excipient and flavor enhancer. The compound’s ability to act as a neurotransmitter has made it a subject of extensive research in neurobiology. Recent studies have highlighted its potential in modulating neural activity, which could have implications for the development of treatments for neurological disorders.

From a biochemical perspective, L-Glutamic acid monosodium salt plays a crucial role in the glutamate-glutamine cycle, which is essential for energy metabolism and neurotransmission. The compound’s monosodium salt form enhances its solubility, making it more effective in aqueous solutions used in laboratory settings and industrial processes. This property is particularly valuable in formulations where stability and bioavailability are critical factors.

In the food industry, L-Glutamic acid monosodium salt is commonly known as MSG (monosodium glutamate), a flavor enhancer that contributes to the savory taste known as umami. Its widespread use underscores its safety and efficacy when used within recommended guidelines. Current research is exploring its role in metabolic health, with studies suggesting potential benefits in managing blood sugar levels and improving insulin sensitivity.

The pharmaceutical applications of L-Glutamic acid monosodium salt extend beyond flavor enhancement. It has been investigated for its potential role in treating conditions such as epilepsy and Alzheimer’s disease. The compound’s ability to modulate glutamate receptors has led to the development of novel therapeutic strategies aimed at improving neuronal communication and reducing excitotoxicity. These findings are particularly relevant given the growing prevalence of neurodegenerative diseases worldwide.

Industrial applications of L-Glutamic acid monosodium salt include its use as a precursor in the synthesis of other amino acids and peptides. Its versatility makes it a valuable intermediate in organic synthesis, enabling the production of complex molecules used in various chemical processes. The compound’s stability under different conditions further enhances its utility in industrial settings where consistent performance is essential.

Recent advancements in biotechnology have also highlighted the importance of L-Glutamic acid monosodium salt in synthetic biology. Researchers are exploring genetically engineered microorganisms capable of producing this compound efficiently, which could reduce production costs and environmental impact. Such innovations align with global efforts to develop sustainable solutions for essential chemicals used across multiple industries.

The safety profile of L-Glutamic acid monosodium salt has been extensively studied, with numerous toxicological assessments confirming its low toxicity when used appropriately. Regulatory agencies such as the FDA and EFSA have approved its use as a food additive based on decades of research supporting its safety. However, ongoing studies continue to monitor potential long-term effects, ensuring that public health remains a priority.

In academic research, L-Glutamic acid monosodium salt serves as a fundamental tool for studying amino acid metabolism and neural function. Its role in cell signaling pathways has opened new avenues for understanding diseases related to neurotransmitter dysregulation. The compound’s availability through reliable suppliers ensures that researchers can conduct experiments with consistency and accuracy.

The environmental impact of producing and using L-Glutamic acid monosodium salt is another area of growing interest. Efforts are underway to optimize production methods to minimize waste and energy consumption. Additionally, researchers are investigating biodegradable packaging solutions to further reduce the ecological footprint associated with this widely used compound.

Future directions for research on L-Glutamic acid monosodium salt include exploring its potential applications in personalized medicine. By understanding individual responses to this compound, healthcare providers could tailor treatments more effectively. This approach aligns with broader trends in medicine toward more targeted and personalized therapeutic strategies.

The economic significance of L-Glutamic acid monosodium salt cannot be overstated. Its widespread use across multiple industries contributes significantly to global markets. As demand grows, so does the importance of ensuring high-quality production standards to meet industry needs without compromising safety or efficacy.

• 91284-29-6(L-Glutamic acid, monosodium salt, pentahydrate (9CI))
• 7558-69-2(L-Glutamic acid,monopotassium monosodium salt (9CI))
• 68187-32-6(L-Glutamic acid, N-cocoacyl derivs., monosodium salts)
• 16177-21-2(L-Glutamic acid, sodiumsalt (1:?))
• 32342-59-9(D-Glutamic acid, sodiumsalt (9CI))
• 32221-81-1(DL-monosodium glutamate)
• 28223-73-6(D-Glutamic acid,disodium salt (9CI))
• 6106-04-3(Monosodium Glutamate Monohydrate)
• 15383-53-6(D-Glutamic acid,monosodium salt (9CI))
• 16690-92-9(L-Glutamic acid, disodiumsalt)