Cas no 1415303-41-1 ((R)-1-(6-Bromopyridin-2-yl)ethanamine hydrochloride)

(R)-1-(6-Bromopyridin-2-yl)ethanamine hydrochloride is a chiral amine derivative featuring a brominated pyridine core, commonly employed as a key intermediate in pharmaceutical and agrochemical synthesis. Its stereospecific (R)-configuration makes it valuable for enantioselective reactions, particularly in the development of bioactive compounds. The bromine substituent at the 6-position enhances reactivity for cross-coupling reactions, such as Suzuki or Buchwald-Hartwig couplings, facilitating further functionalization. The hydrochloride salt form improves stability and handling, ensuring consistent performance in synthetic applications. This compound is particularly useful in asymmetric catalysis and the preparation of ligands or active pharmaceutical ingredients (APIs) requiring precise chirality. High purity and well-defined stereochemistry make it a reliable choice for research and industrial applications.
(R)-1-(6-Bromopyridin-2-yl)ethanamine hydrochloride structure
1415303-41-1 structure
Product Name:(R)-1-(6-Bromopyridin-2-yl)ethanamine hydrochloride
CAS No:1415303-41-1
MF:C7H10BrClN2
MW:237.524699687958
MDL:MFCD12759736
CID:4595245
PubChem ID:117820260
Update Time:2025-11-06

(R)-1-(6-Bromopyridin-2-yl)ethanamine hydrochloride Chemical and Physical Properties

Names and Identifiers

    • (R)-1-(6-Bromopyridin-2-yl)ethanamine hydrochloride
    • (R)-1-(6-Bromopyridin-2-yl)ethanamine HCl
    • (1R)-1-(6-bromopyridin-2-yl)ethanamine;hydrochloride
    • CS-0186111
    • (1R)-1-(6-bromopyridin-2-yl)ethanamine hydrochloride
    • BS-15057
    • (1R)-1-(6-Bromo-2-pyridyl)ethanamine hydrochloride
    • MFCD12759736
    • AKOS027334563
    • (R)-1-(6-Bromopyridin-2-yl)ethanaminehydrochloride
    • DS-018857
    • 1415303-41-1
    • (R)-1-(6-bromopyridin-2-yl)ethan-1-amine hydrochloride
    • SCHEMBL16397042
    • MDL: MFCD12759736
    • Inchi: 1S/C7H9BrN2.ClH/c1-5(9)6-3-2-4-7(8)10-6;/h2-5H,9H2,1H3;1H/t5-;/m1./s1
    • InChI Key: RITFLBZVEWSGLF-NUBCRITNSA-N
    • SMILES: BrC1=CC=CC([C@@H](C)N)=N1.Cl

Computed Properties

  • Exact Mass: 235.97159g/mol
  • Monoisotopic Mass: 235.97159g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 11
  • Rotatable Bond Count: 1
  • Complexity: 108
  • Covalently-Bonded Unit Count: 2
  • Defined Atom Stereocenter Count: 1
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 38.9

(R)-1-(6-Bromopyridin-2-yl)ethanamine hydrochloride Pricemore >>

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Additional information on (R)-1-(6-Bromopyridin-2-yl)ethanamine hydrochloride

Comprehensive Overview of (R)-1-(6-Bromopyridin-2-yl)ethanamine hydrochloride (CAS No. 1415303-41-1)

(R)-1-(6-Bromopyridin-2-yl)ethanamine hydrochloride (CAS No. 1415303-41-1) is a chiral organic compound with significant applications in pharmaceutical research and fine chemical synthesis. This compound, characterized by its 6-bromopyridin-2-yl moiety and ethylamine functional group, is widely utilized as a key intermediate in the development of bioactive molecules. Its hydrochloride salt form enhances stability and solubility, making it a preferred choice for laboratory and industrial applications.

The growing interest in chiral amines like (R)-1-(6-Bromopyridin-2-yl)ethanamine hydrochloride stems from their pivotal role in asymmetric synthesis and drug discovery. Researchers are increasingly focusing on enantioselective catalysis and pharmaceutical intermediates, aligning with trends in personalized medicine and green chemistry. The compound’s bromopyridine scaffold is particularly valuable for cross-coupling reactions, a hot topic in modern organic chemistry due to its efficiency in constructing complex molecular architectures.

From an SEO perspective, users frequently search for terms such as "synthesis of (R)-1-(6-Bromopyridin-2-yl)ethanamine hydrochloride", "CAS 1415303-41-1 applications", and "chiral amine derivatives in drug development". These queries reflect the compound’s relevance in academic and industrial settings. Additionally, the rise of AI-driven drug design has spurred demand for high-purity intermediates like this, as computational models increasingly predict their utility in targeted therapies.

Quality control is another critical aspect of (R)-1-(6-Bromopyridin-2-yl)ethanamine hydrochloride. Analytical techniques such as HPLC, NMR, and mass spectrometry are essential to verify its enantiomeric purity and chemical integrity. Suppliers often highlight GMP compliance and batch-to-batch consistency, addressing concerns raised by pharmaceutical manufacturers about raw material reliability.

Environmental and regulatory considerations also shape the discourse around this compound. With the pharmaceutical industry emphasizing sustainable synthesis, researchers explore greener alternatives for producing (R)-1-(6-Bromopyridin-2-yl)ethanamine hydrochloride, such as biocatalysis or solvent-free reactions. This aligns with global initiatives like the UN Sustainable Development Goals (SDGs), particularly SDG 12 (Responsible Consumption and Production).

In summary, (R)-1-(6-Bromopyridin-2-yl)ethanamine hydrochloride (CAS No. 1415303-41-1) represents a versatile building block in medicinal chemistry, with its chiral specificity and reactivity driving innovation. Its intersection with trending topics—AI-aided drug discovery, green chemistry, and high-throughput screening—ensures its continued prominence in scientific literature and industrial workflows.

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