Cas no 1415250-03-1 ((5-Amino-2,3-difluorophenyl)methanol)
(5-Amino-2,3-difluorophenyl)methanol Chemical and Physical Properties
Names and Identifiers
-
- (5-Amino-2,3-difluorophenyl)methanol
- LHPNJBAMXBZVGP-UHFFFAOYSA-N
- SB84683
- SCHEMBL14060828
- DTXSID30858652
- Benzenemethanol, 5-amino-2,3-difluoro-
- 1415250-03-1
-
- Inchi: 1S/C7H7F2NO/c8-6-2-5(10)1-4(3-11)7(6)9/h1-2,11H,3,10H2
- InChI Key: LHPNJBAMXBZVGP-UHFFFAOYSA-N
- SMILES: FC1=C(C=C(C=C1CO)N)F
Computed Properties
- Exact Mass: 159.04957017g/mol
- Monoisotopic Mass: 159.04957017g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 2
- Hydrogen Bond Acceptor Count: 2
- Heavy Atom Count: 11
- Rotatable Bond Count: 1
- Complexity: 134
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- XLogP3: 0.6
- Topological Polar Surface Area: 46.2?2
(5-Amino-2,3-difluorophenyl)methanol Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Alichem | A019118309-1g |
(5-Amino-2,3-difluorophenyl)methanol |
1415250-03-1 | 95% | 1g |
400.00 USD | 2021-06-16 | |
| Crysdot LLC | CD12145045-1g |
(5-Amino-2,3-difluorophenyl)methanol |
1415250-03-1 | 95+% | 1g |
$464 | 2024-07-23 |
(5-Amino-2,3-difluorophenyl)methanol Related Literature
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Haitao Li,Yu Pan,Zhizhi Wang,Shan Chen,Ruixin Guo,Jianqiu Chen RSC Adv., 2015,5, 100775-100782
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Adeline Huiling Loo,Alessandra Bonanni,Martin Pumera Analyst, 2013,138, 467-471
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Kaiyuan Huang,Wangkang Qiu,Meilian Ou,Xiaorui Liu,Zenan Liao,Sheng Chu RSC Adv., 2020,10, 18824-18829
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Inês S. Albuquerque,Hélia F. Jeremias,Miguel Chaves-Ferreira,Dijana Matak-Vinkovic,Omar Boutureira,Carlos C. Rom?o Chem. Commun., 2015,51, 3993-3996
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P. K. Wawrzyniak,M. T. P. Beerepoot,H. J. M. de Groot,F. Buda Phys. Chem. Chem. Phys., 2011,13, 10270-10279
Additional information on (5-Amino-2,3-difluorophenyl)methanol
Introduction to (5-Amino-2,3-difluorophenyl)methanol (CAS No. 1415250-03-1)
Compound with the CAS number 1415250-03-1 and the product name (5-Amino-2,3-difluorophenyl)methanol represents a significant advancement in the field of chemical and pharmaceutical research. This compound, characterized by its unique structural and functional properties, has garnered considerable attention in recent years due to its potential applications in various biomedical and industrial domains.
The molecular structure of (5-Amino-2,3-difluorophenyl)methanol consists of a phenyl ring substituted with amino and fluorine atoms at the 5th and 2nd, 3rd positions, respectively, with a hydroxymethyl group attached to the 1st position. This specific arrangement imparts distinct reactivity and binding capabilities, making it a valuable intermediate in the synthesis of complex molecules.
In recent years, there has been a growing interest in exploring the pharmacological properties of fluorinated aromatic compounds. The presence of fluorine atoms in (5-Amino-2,3-difluorophenyl)methanol enhances its metabolic stability and binding affinity to biological targets. This has led to numerous studies investigating its potential as a precursor in the development of novel therapeutic agents.
One of the most compelling aspects of this compound is its role in the synthesis of bioactive molecules. Researchers have leveraged its structural features to develop inhibitors targeting various enzymes and receptors involved in critical biological pathways. For instance, studies have demonstrated its utility in creating compounds that modulate kinases and transcription factors, which are key players in cancer and inflammatory diseases.
The fluorinated aromatic ring in (5-Amino-2,3-difluorophenyl)methanol also contributes to its stability under various chemical conditions, making it an ideal candidate for multi-step synthetic protocols. This stability is particularly advantageous in pharmaceutical manufacturing, where high yields and purity are essential for producing safe and effective drugs.
Recent advancements in computational chemistry have further enhanced the understanding of how (5-Amino-2,3-difluorophenyl)methanol interacts with biological systems. Molecular docking studies have revealed that this compound can bind to specific pockets on target proteins with high affinity. These insights have guided the design of more potent derivatives with improved pharmacokinetic profiles.
The pharmaceutical industry has been particularly keen on exploring fluorinated compounds due to their favorable pharmacological properties. The incorporation of fluorine atoms into drug molecules often leads to increased bioavailability, reduced metabolic clearance, and enhanced therapeutic efficacy. (5-Amino-2,3-difluorophenyl)methanol exemplifies this trend by serving as a versatile building block for innovative drug candidates.
Beyond pharmaceutical applications, this compound has shown promise in materials science. Its unique electronic properties make it suitable for use in organic electronics and optoelectronic devices. Researchers are investigating its potential as a component in light-emitting diodes (LEDs) and photovoltaic cells, where its ability to absorb and emit light efficiently is highly valued.
The synthesis of (5-Amino-2,3-difluorophenyl)methanol involves multi-step organic reactions that highlight the compound's synthetic utility. Advanced catalytic methods have been employed to achieve high selectivity and yield during its production. These synthetic strategies not only facilitate the preparation of this compound but also provide valuable insights into developing similar fluorinated aromatic derivatives.
In conclusion, the compound with CAS number 1415250-03-1, known as (5-Amino-2,3-difluorophenyl)methanol, represents a cornerstone in modern chemical research. Its unique structural features and functional properties make it indispensable in pharmaceutical development, materials science, and beyond. As research continues to uncover new applications for this compound, its significance is expected to grow even further.
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