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• 2. Evolution of cellulose into flexible conductive green electronics: a smart strategy to fabricate sustainable electrodes for supercapacitors
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• Solvents and Organic Chemicals Organic Compounds Amines/Sulfonamides

Professional Introduction to 1-Aminononadecane (CAS No. 14130-05-3)

1-Aminononadecane, with the chemical formula C₁₉H₄₁N, is a long-chain primary amine that has garnered significant attention in the field of chemical and pharmaceutical research. This compound, identified by its unique CAS number 14130-05-3, is characterized by its linear aliphatic structure, which consists of a nonadecane backbone substituted with an amino group at one end. The molecular weight of this compound is approximately 285.53 g/mol, making it a relatively heavy molecule compared to shorter-chain amines.

The significance of 1-Aminononadecane in modern research stems from its versatile applications across multiple domains, including drug delivery systems, polymer chemistry, and material science. Its long hydrocarbon chain provides excellent solubility in organic solvents, while the primary amine group allows for further functionalization through reactions such as esterification, amidation, and coupling with other biomolecules. These properties make it a valuable building block in the synthesis of complex molecules.

In recent years, 1-Aminononadecane has been explored for its potential in pharmaceutical applications. One of the most promising areas is its use as a component in micellar drug delivery systems. Micelles are nano-sized structures that can encapsulate hydrophobic drugs, enhancing their solubility and bioavailability. The long alkyl chain of 1-Aminononadecane facilitates the formation of stable micelles, while the amine group can be modified to incorporate targeting ligands or therapeutic agents. Studies have shown that micelles derived from 1-Aminononadecane can effectively deliver payloads to specific sites in the body, improving therapeutic outcomes.

The compound has also found utility in polymer chemistry, particularly in the development of biodegradable polymers. The linear structure of 1-Aminononadecane allows it to serve as a monomer or modifier in polyamide and polyester synthesis. These polymers are widely used in medical implants, sutures, and controlled-release formulations due to their biocompatibility and degradation properties. Researchers have been particularly interested in modifying the properties of these polymers by incorporating functional groups like amines to enhance their interactions with biological tissues.

In material science, 1-Aminononadecane is being investigated for its role in creating novel materials with enhanced thermal and mechanical properties. Its long hydrocarbon chain contributes to high thermal stability, making it suitable for high-performance coatings and adhesives. Additionally, the primary amine group can be cross-linked with other molecules to form rigid networks or gels with specific mechanical properties. Such materials are being explored for applications in aerospace, automotive industries, and advanced composites.

The latest research on 1-Aminononadecane has also delved into its potential as a ligand for metal-organic frameworks (MOFs). MOFs are porous materials composed of metal ions or clusters coordinated with organic ligands. The amine group of 1-Aminononadecane can act as a ligand for metal centers, allowing for the design of MOFs with tailored porosity and selectivity. These MOFs have applications in gas storage, separation technologies, and catalysis. Recent studies have demonstrated that MOFs incorporating 1-Aminononadecane ligands exhibit high surface areas and selective adsorption capabilities for small molecules.

The synthesis of derivatives of CAS no 14130-05-3, such as N-substituted nonadecanamines or nonadecanamides, has been another area of active investigation. These derivatives exhibit modified physicochemical properties that make them suitable for different applications. For instance, N-substituted derivatives can be used as surfactants or emulsifiers due to their ability to lower surface tension and stabilize emulsions. Nonadecanamides have shown promise as intermediates in the synthesis of bioactive molecules.

The industrial production of 1-Aminononadecane typically involves the reduction of nonadecanoic acid or its esters using reducing agents such as lithium aluminum hydride (LiAlH₄) or hydrogen gas over catalysts like palladium on carbon (Pd/C). Alternatively, alkylation reactions starting from nonene precursors can be employed to introduce the amino group at the desired position on the carbon chain. The choice of synthetic route depends on factors such as cost-effectiveness, scalability, and environmental considerations.

The safety profile of CAS no 14130-05-3, when handled under appropriate conditions, is generally favorable. However, like many organic compounds with long hydrocarbon chains, it may pose risks if ingested or exposed to skin or eyes for prolonged periods. Proper ventilation and personal protective equipment (PPE) should be used during handling to minimize exposure risks. Storage conditions should also be carefully controlled to prevent degradation or unwanted reactions.

The future prospects for research involving CAS no 14130-05-3, including 1-Aminononadecane derivatives and related compounds, appear highly promising. Advances in synthetic methodologies will continue to expand the library of available derivatives with tailored properties for specific applications. Additionally, interdisciplinary approaches combining chemistry with biology and materials science will likely uncover new uses for this versatile compound.

In conclusion,
CAS no 14130-05-3 , specifically 1-Aminononadecane , represents an important compound with broad applicability across various scientific fields.
Its unique structural features enable diverse modifications
leading to novel materials,
pharmaceutical formulations,
and advanced technological solutions.
As research progresses,
the full potential
of this remarkable molecule
is expected
to become increasingly evident.
The ongoing exploration
of its derivatives
and synthetic pathways
will undoubtedly contribute
to significant advancements
in multiple domains.

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