• 1. Embedding cyclic nitrone in mesoporous silica particles for EPR spin trapping of superoxide and other radicals?
  Eric Besson,Stéphane Gastaldi,Emily Bloch,Selma Aslan,Hakim Karoui,Olivier Ouari,Micael Hardy Analyst, 2019,144, 4194-4203
• 2. Evolution of calcium phosphate precipitation in hanging drop vapor diffusion by in situRaman microspectroscopy
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• 3. Enabling chloride salts for thermal energy storage: implications of salt purity?
  J. Matthew Kurley,Phillip W. Halstenberg,Abbey McAlister,Stephen Raiman,Richard T. Mayes RSC Adv., 2019,9, 25602-25608
• 4. Excellent electrochemical performance of LiFe0.4Mn0.6PO4 microspheres produced using a double carbon coating process?
  Yong Ping Huang,Tao Tao,Zheng Chen,Wei Han,Ying Wu,Chunjiang Kuang,Shaoxiong Zhou,Ying Chen J. Mater. Chem. A, 2014,2, 18831-18837
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• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Pyrrolines Pyrroline carboxylic acids and derivatives Pyrroline carboxylic acids

Comprehensive Overview of Tert-Butyl 2-oxo-2,5-dihydro-1H-pyrrole-1-carboxylate (CAS No. 141293-14-3)

Tert-Butyl 2-oxo-2,5-dihydro-1H-pyrrole-1-carboxylate (CAS No. 141293-14-3) is a versatile organic compound widely utilized in pharmaceutical and agrochemical research. This compound belongs to the class of pyrrole derivatives, which are known for their significant biological activities and applications in drug discovery. The tert-butyl group and carboxylate moiety in its structure make it a valuable intermediate for synthesizing more complex molecules.

In recent years, the demand for pyrrole-based compounds has surged due to their role in developing anticancer agents, antimicrobial drugs, and anti-inflammatory medications. Researchers are particularly interested in Tert-Butyl 2-oxo-2,5-dihydro-1H-pyrrole-1-carboxylate because of its potential to act as a building block for heterocyclic compounds. Its unique structure allows for further functionalization, enabling the creation of novel therapeutic agents.

The synthesis of Tert-Butyl 2-oxo-2,5-dihydro-1H-pyrrole-1-carboxylate typically involves the reaction of pyrrole derivatives with tert-butyl dicarbonate under controlled conditions. This process highlights the compound's relevance in organic synthesis and medicinal chemistry. Its stability and solubility in common organic solvents further enhance its utility in laboratory settings.

One of the most frequently asked questions about Tert-Butyl 2-oxo-2,5-dihydro-1H-pyrrole-1-carboxylate is its role in drug development. Recent studies have explored its potential as a precursor for kinase inhibitors, which are crucial in treating various diseases, including cancer and autoimmune disorders. Additionally, its application in peptide synthesis has garnered attention, as it can be used to protect amino groups during solid-phase peptide synthesis (SPPS).

Another area of interest is the compound's use in agrochemical research. Pyrrole derivatives are known for their pesticidal and herbicidal properties, making Tert-Butyl 2-oxo-2,5-dihydro-1H-pyrrole-1-carboxylate a candidate for developing new crop protection agents. Its ability to modify biological pathways in pests and weeds underscores its importance in sustainable agriculture.

From a commercial perspective, Tert-Butyl 2-oxo-2,5-dihydro-1H-pyrrole-1-carboxylate is available in high purity grades, catering to the needs of pharmaceutical manufacturers and research institutions. Suppliers often provide detailed technical data sheets (TDS) and material safety data sheets (MSDS) to ensure safe handling and compliance with regulatory standards.

In conclusion, Tert-Butyl 2-oxo-2,5-dihydro-1H-pyrrole-1-carboxylate (CAS No. 141293-14-3) is a pivotal compound in modern chemistry, bridging the gap between academic research and industrial applications. Its multifaceted uses in drug discovery, peptide synthesis, and agrochemical development make it a subject of ongoing exploration and innovation.

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