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• 2. Evolution of shape, size, and areal density of a single plane of Si nanocrystals embedded in SiO2 matrix studied by atom probe tomography
  Bin Han,Yasuo Shimizu,Gabriele Seguini,Celia Castro,Gérard Ben Assayag,Koji Inoue,Yasuyoshi Nagai,Sylvie Schamm-Chardon,Michele Perego RSC Adv., 2016,6, 3617-3622
• 3. Dissolved oxygen sensor based on fluorescence quenching of oxygen-sensitive ruthenium complexes immobilized in sol–gel-derived porous silica coatings
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• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Pyrrolidines Pyrrolidines
• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Pyrrolidines

2-(Pyrrolidin-3-yloxy)ethan-1-ol: A Comprehensive Overview

2-(Pyrrolidin-3-yloxy)ethan-1-ol (CAS No. 1404531-37-8) is a versatile organic compound with a unique chemical structure that has garnered significant attention in recent years. This compound, often referred to as pyrrolidinyl ether alcohol, belongs to the class of heterocyclic ethers and exhibits a wide range of applications in various fields, including pharmaceuticals, agrochemicals, and materials science. Its molecular formula is C7H15NO2, and its molecular weight is approximately 145.2 g/mol.

The structure of 2-(pyrrolidin-3-yloxy)ethan-1-ol consists of a pyrrolidine ring (a five-membered saturated heterocycle containing one nitrogen atom) attached to an ether group (-O-) and a hydroxyl group (-OH) via an ethylene chain. This arrangement imparts the compound with unique physical and chemical properties, such as moderate solubility in water and good stability under physiological conditions. The presence of the hydroxyl group also makes it amenable to various functionalization reactions, further expanding its utility.

Recent studies have highlighted the potential of 2-(pyrrolidin-3-yloxy)ethan-1-ol as a building block in medicinal chemistry. Researchers have explored its ability to act as a bioisostere in drug design, where it can replace other functional groups without significantly altering the overall pharmacokinetic profile of a molecule. This property has been particularly useful in developing small molecule inhibitors targeting key enzymes involved in diseases such as cancer and neurodegenerative disorders.

In addition to its role in drug discovery, 2-(pyrrolidin-3-yloxy)ethan-1-ol has also found applications in the synthesis of advanced materials. For instance, it has been used as a precursor for the preparation of block copolymers with tunable mechanical properties. These polymers exhibit excellent thermal stability and are being investigated for use in high-performance adhesives and coatings.

The synthesis of 2-(pyrrolidin-3-yloxy)ethan-1-ol typically involves multi-step reactions, often starting from readily available starting materials such as pyrrolidine and epoxides. Recent advancements in catalytic methods have enabled more efficient and environmentally friendly routes to this compound, reducing production costs and minimizing waste generation.

From an environmental perspective, 2-(pyrrolidin-3-yloxy)ethan-1-ol has shown biodegradability under aerobic conditions, making it a more sustainable choice compared to some traditional organic compounds used in industrial applications. This characteristic aligns with the growing emphasis on green chemistry principles in modern chemical manufacturing.

In conclusion, 2-(pyrrolidin-3-yloxy)ethan-1-ol (CAS No. 1404531-37-) is a multifaceted compound with promising prospects across diverse industries. Its unique structure, combined with recent breakthroughs in its synthesis and application, positions it as a valuable tool for researchers and industry professionals alike. As ongoing studies continue to uncover new functionalities and optimizations for this compound, its role in advancing science and technology is expected to grow significantly.

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