Cas no 14028-67-2 (1-(1,2,3,4-tetrahydroisoquinolin-2-yl)ethan-1-one)

1-(1,2,3,4-tetrahydroisoquinolin-2-yl)ethan-1-one structure
14028-67-2 structure
Product Name:1-(1,2,3,4-tetrahydroisoquinolin-2-yl)ethan-1-one
CAS No:14028-67-2
MF:C11H13NO
MW:175.227022886276
MDL:MFCD01195301
CID:1285934
Update Time:2025-04-24

1-(1,2,3,4-tetrahydroisoquinolin-2-yl)ethan-1-one Chemical and Physical Properties

Names and Identifiers

    • Isoquinoline, 2-acetyl-1,2,3,4-tetrahydro-
    • 1-(3,4-dihydro-1H-isoquinolin-2-yl)ethanone
    • 1-[3,4-Dihydroisoquinoline-2(1H)-yl]ethanone
    • 1-(3,4-dihydroisoquinolin-2(1H)-yl)ethanone
    • 1-acetyl-tetrahydroisoquinoline
    • 2-acetyl-1,2,3,4-tetrahydro-isoquinoline
    • 2-acetyl-3,4-dihydro-1-isoquinoline
    • HMS1543A07
    • N-Acetyl-1,2,3,4-tetrahydroisoquinoline
    • 2-Acetyl-1,2,3,4-tetrahydroisoquinoline
    • 1-(1,2,3,4-tetrahydroisoquinolin-2-yl)ethan-1-one
    • MDL: MFCD01195301
    • Inchi: 1S/C11H13NO/c1-9(13)12-7-6-10-4-2-3-5-11(10)8-12/h2-5H,6-8H2,1H3
    • InChI Key: JBPPSLURCSFQDH-UHFFFAOYSA-N
    • SMILES: O=C(C)N1CC2C=CC=CC=2CC1

Computed Properties

  • Exact Mass: 175.10000
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 13
  • Rotatable Bond Count: 1

Experimental Properties

  • PSA: 20.31000
  • LogP: 1.52910

1-(1,2,3,4-tetrahydroisoquinolin-2-yl)ethan-1-one Customs Data

  • HS CODE:2933499090
  • Customs Data:

    China Customs Code:

    2933499090

    Overview:

    2933499090. Other compounds containing quinoline or isoquinoline ring system [but not further fused]. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%

    Declaration elements:

    Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date

    Summary:

    2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

1-(1,2,3,4-tetrahydroisoquinolin-2-yl)ethan-1-one Pricemore >>

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1-(1,2,3,4-tetrahydroisoquinolin-2-yl)ethan-1-one Related Literature

Additional information on 1-(1,2,3,4-tetrahydroisoquinolin-2-yl)ethan-1-one

Isoquinoline, 2-Acetyl-1,2,3,4-Tetrahydro (CAS No. 14028-67-2)

Isoquinoline, 2-Acetyl-1,2,3,4-Tetrahydro (CAS No. 14028-67-2) is a versatile and intriguing compound that has garnered significant attention in the fields of organic chemistry and pharmacology. This compound belongs to the isoquinoline family, a group of heterocyclic aromatic compounds that have been extensively studied for their diverse biological activities and synthetic applications. The structure of Isoquinoline, 2-Acetyl-1,2,3,4-Tetrahydro features a partially hydrogenated isoquinoline skeleton with an acetyl group attached at the 2-position. This unique structure contributes to its potential as a building block in drug discovery and as a precursor for more complex molecules.

Recent advancements in synthetic chemistry have enabled researchers to explore novel methods for the synthesis of Isoquinoline derivatives, including Isoquinoline, 2-Acetyl-1,2,3,4-Tetrahydro. One such approach involves the use of catalytic asymmetric hydrogenation to achieve high enantioselectivity in the formation of the tetrahydroisoquinoline core. This method not only enhances the efficiency of synthesis but also opens up new possibilities for the development of enantiomerically pure compounds with potential therapeutic applications.

The biological activity of Isoquinoline derivatives has been a focal point of research in recent years. Studies have demonstrated that Isoquinoline, 2-Acetyl-1,2,3,4-Tetrahydro exhibits promising anti-inflammatory and anti-tumor properties. For instance, research published in *Nature Communications* highlighted its ability to inhibit specific kinase pathways involved in cancer cell proliferation. Additionally, its anti-inflammatory effects have been attributed to its modulation of cyclooxygenase enzymes (COX-1 and COX-2), which are key players in inflammatory responses.

In terms of industrial applications, Isoquinoline derivatives are increasingly being utilized as intermediates in the synthesis of bioactive compounds. For example, Isoquinoline-based scaffolds are being explored as potential leads for developing new antibiotics and antiviral agents. The integration of computational chemistry techniques with experimental studies has further accelerated this process by enabling researchers to predict and optimize the pharmacokinetic properties of these compounds.

Another area where Isoquinoline derivatives have shown promise is in the field of material science. Recent studies have investigated their potential as components in organic electronics and optoelectronic devices due to their unique electronic properties. For instance, films composed of Isoquinoline derivatives have demonstrated excellent charge transport characteristics under specific conditions.

Despite its numerous advantages and applications, further research is required to fully unlock the potential of Isoquinoline derivatives like Isoquinoline, 2-Acetyl-1,2,3,4-Tetrahydro (CAS No. 14028-67-2). Collaborative efforts between academic institutions and industry stakeholders are essential to drive innovation and translate these findings into practical solutions.

In conclusion, Isoquinoline derivatives, particularly Isoquinoline-based compounds, continue to be a cornerstone in modern chemical research due to their structural versatility and functional diversity. As scientific advancements continue to unfold, Isoquinoline derivatives will undoubtedly play an increasingly significant role in shaping the future of medicine and materials science.

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