• 1. Evolution of calcium phosphate precipitation in hanging drop vapor diffusion by in situRaman microspectroscopy
  Gloria Belén Ramírez-Rodríguez,José Manuel Delgado-López,Jaime Gómez-Morales CrystEngComm, 2013,15, 2206-2212
• 2. Emulsifier-free, organotellurium-mediated living radical emulsion polymerization (emulsion TERP) of styrene: poly(dimethylaminoethyl methacrylate) macro-TERP agent?
  Yukiya Kitayama Polym. Chem., 2014,5, 2784-2792
• 3. Excitation energies from ground-state density-functionals by means of generator coordinates
  A. B. F. da Silva,K. Capelle Phys. Chem. Chem. Phys., 2009,11, 4564-4569
• 4. Fate of single walled carbon nanotubes in wetland ecosystems?
  Joseph H. Bisesi,Tara Sabo-Attwood Environ. Sci.: Nano, 2014,1, 574-583
• 5. Evolution and characterization of a benzylguanine-binding RNA aptamer?
  J. Xu,T. J. Carrocci,A. A. Hoskins Chem. Commun., 2016,52, 549-552

• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Diazanaphthalenes Cinnolines
• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Diazanaphthalenes Benzodiazines Cinnolines

Exploring 3-Cinnolinecarboxylic acid, 7-bromo- (CAS No. 1402672-23-4): A Versatile Compound in Modern Research

In the realm of heterocyclic chemistry, 3-Cinnolinecarboxylic acid, 7-bromo- (CAS No. 1402672-23-4) has emerged as a compound of significant interest due to its unique structural properties and potential applications. This cinnoline derivative is characterized by a bromine substitution at the 7-position, which enhances its reactivity and utility in various synthetic pathways. Researchers are increasingly focusing on this compound for its role in pharmaceutical intermediates and material science, aligning with the growing demand for novel bioactive molecules and advanced functional materials.

The 7-bromo substitution in 3-Cinnolinecarboxylic acid offers distinct advantages in cross-coupling reactions, a topic frequently searched in modern organic chemistry forums. This feature makes it a valuable building block for constructing complex molecular architectures, such as drug candidates or organic electronic materials. Recent studies highlight its potential in catalysis and ligand design, addressing trending queries like "how to optimize Suzuki-Miyaura reactions" or "new brominated heterocycles for OLEDs."

From a synthetic perspective, the carboxylic acid group in 3-Cinnolinecarboxylic acid, 7-bromo- enables diverse derivatization strategies. This aligns with the current focus on green chemistry and atom economy, as researchers seek efficient methods to functionalize such scaffolds. Popular search terms like "sustainable synthesis of cinnoline derivatives" or "bromo-substituted heterocycles in medicinal chemistry" reflect this trend, underscoring the compound's relevance in contemporary research.

Analytical techniques such as NMR spectroscopy and HPLC-MS are critical for characterizing CAS No. 1402672-23-4, a point often raised in academic discussions about quality control in fine chemical production. The compound's stability under various conditions is another area of investigation, responding to practical questions like "how to store brominated cinnoline derivatives" or "solubility of 7-bromo-3-cinnolinecarboxylic acid."

In the context of intellectual property, 3-Cinnolinecarboxylic acid, 7-bromo- has been cited in several patent applications related to kinase inhibitors and antimicrobial agents. This connects to the broader interest in "new heterocyclic compounds for drug discovery," a frequently searched phrase in scientific databases. Its structural motif is also explored in computational chemistry studies, addressing the rising popularity of AI-driven molecular design tools.

As regulatory standards evolve, the compound's safety profile and environmental impact are under scrutiny, mirroring public concerns about "sustainable chemical innovation." Researchers emphasize the need for proper waste management protocols when handling brominated compounds, a topic gaining traction in industrial chemistry circles.

The future of 3-Cinnolinecarboxylic acid, 7-bromo- lies in its adaptability to emerging technologies. With growing interest in high-throughput screening and combinatorial chemistry, this compound may play a pivotal role in accelerating the discovery of next-generation therapeutics and functional materials, answering the persistent question: "What are the most promising heterocycles for 21st-century applications?"

• 332062-08-5(Fmoc-S-3-amino-4,4-diphenyl-butyric acid)
• 1270529-38-8(1,2,3,4,5,6-Hexahydro-[2,3]bipyridinyl-6-ol)
• 2680771-01-9(4-cyclopentyl-3-{(prop-2-en-1-yloxy)carbonylamino}butanoic acid)
• 2098070-20-1(2-(3-(Pyridin-3-yl)-1H-pyrazol-1-yl)acetimidamide)
• 1444113-98-7(N-(3-cyanothiolan-3-yl)-2-[(2,2,2-trifluoroethyl)sulfanyl]pyridine-4-carboxamide)
• 941977-17-9(N'-(3-chloro-2-methylphenyl)-N-2-(dimethylamino)-2-(naphthalen-1-yl)ethylethanediamide)
• 2138166-62-6(2,2-Difluoro-3-[methyl(2-methylbutyl)amino]propanoic acid)
• 89640-58-4(2-Iodo-4-nitrophenylhydrazine)
• 1449132-38-0(3-Fluoro-5-(2-fluoro-5-methylbenzylcarbamoyl)benzeneboronic acid)
• 2034271-14-0(2-(1H-indol-3-yl)-N-{[6-(thiophen-2-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]methyl}acetamide)