• 1. An aptasensor for the detection of ampicillin in milk using a personal glucose meter
  Xixi Li,Nanwei Zhu,Ruohan Li,Qinpu Zhang Anal. Methods, 2020,12, 3376-3381
• 2. An approach to biodegradable star polymeric architectures using disulfide coupling?
  Jingquan Liu,Huiyun Liu,Zhongfan Jia,Volga Bulmus,Thomas P. Davis Chem. Commun., 2008, 6582-6584
• 3. An amide probe as a selective Al3+ and Fe3+ sensor inside the HeLa and a549 cell lines: Pictet–Spengler reaction for the rapid detection of tryptophan amino acid?
  Bidyut Kumar Kundu,Rinky Singh,Ritudhwaj Tiwari,Debasis Nayak New J. Chem., 2019,43, 4867-4877
• 4. An amorphous lanthanum–iridium solid solution with an open structure for efficient water splitting?
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• 5. An aptasensor for detection of potassium ions based on RecJf exonuclease mediated signal amplification
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• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Biphenyls and derivatives

Comprehensive Overview of [1,1'-Biphenyl]-2-carboxylic acid, 4,4'-difluoro-3'-methyl- (CAS No. 139911-15-2)

The chemical compound [1,1'-Biphenyl]-2-carboxylic acid, 4,4'-difluoro-3'-methyl- (CAS No. 139911-15-2) is a specialized organic molecule that has garnered significant attention in pharmaceutical and material science research. This biphenyl derivative is characterized by its unique structural features, including a carboxylic acid group at the 2-position and difluoro and methyl substitutions at the 4,4' and 3' positions, respectively. Its molecular formula is C₁₄H₁₀F₂O₂, and it is widely studied for its potential applications in drug development and advanced materials.

In recent years, the demand for fluorinated biphenyl compounds has surged due to their enhanced stability and bioavailability, making them ideal candidates for medicinal chemistry. Researchers are particularly interested in CAS 139911-15-2 for its potential role in designing small-molecule inhibitors and ligands for therapeutic targets. The presence of fluorine atoms in the compound improves its metabolic stability, a critical factor in the development of next-generation pharmaceuticals.

From a synthetic perspective, [1,1'-Biphenyl]-2-carboxylic acid, 4,4'-difluoro-3'-methyl- is often synthesized via Suzuki-Miyaura coupling, a widely used method for constructing biphenyl scaffolds. The compound's crystalline structure and solubility properties have been extensively studied to optimize its use in various formulations. Its thermal stability also makes it a promising candidate for high-performance polymers and electronic materials.

Environmental and regulatory considerations are also key topics surrounding this compound. As the industry shifts toward green chemistry, researchers are exploring sustainable synthesis routes for 139911-15-2 to minimize waste and energy consumption. Additionally, its low toxicity profile aligns with the growing demand for eco-friendly chemicals in industrial applications.

For those searching for where to buy [1,1'-Biphenyl]-2-carboxylic acid, 4,4'-difluoro-3'-methyl-, it is essential to source the compound from reputable suppliers who provide high-purity grades and detailed analytical certificates. The compound is typically available in milligram to kilogram quantities, catering to both research and industrial-scale needs.

In summary, CAS 139911-15-2 represents a versatile and valuable compound in modern chemistry. Its applications span pharmaceutical intermediates, material science, and beyond, making it a subject of ongoing research and innovation. As scientific advancements continue, this difluoromethyl biphenyl derivative is poised to play a pivotal role in addressing some of the most pressing challenges in chemistry and biotechnology.

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