• 1. Evidence of pre-micellar aggregates in aqueous solution of amphiphilic PDMS–PEO block copolymer?
  Domenico Lombardo,Gianmarco Munaò,Pietro Calandra,Luigi Pasqua,Maria Teresa Caccamo Phys. Chem. Chem. Phys., 2019,21, 11983-11991
• 2. Fe3O4 nanoparticle chains with N-doped carbon coating: magnetotactic bacteria assisted synthesis and high-rate lithium storage?
  Dan Yang,Yanping Zhou,Xianhong Rui,Jixin Zhu,Ziyang Lu,Eileen Fong,Qingyu Yan RSC Adv., 2013,3, 14960-14962
• 3. Evolved polymerases facilitate selection of fully 2′-OMe-modified aptamers?
  Zhixia Liu,Tingjian Chen,Floyd E. Romesberg Chem. Sci., 2017,8, 8179-8182
• 4. Embedding heteroatoms: an effective approach to create porphyrin-based functional materials
  Norihito Fukui,Keisuke Fujimoto,Hideki Yorimitsu,Atsuhiro Osuka Dalton Trans., 2017,46, 13322-13341
• 5. Establishing the accuracy of position-specific carbon isotope analysis of propane by GC-pyrolysis-GC-IRMS
  ChangjieLiu,PengLiu,XiaofengWang,XiaoqiangLi,JuskeHorita

• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Quinolines and derivatives Chloroquinolines
• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Quinolines and derivatives Haloquinolines Chloroquinolines

2-Chloro-4,6,8-Trimethylquinoline: A Comprehensive Overview

2-Chloro-4,6,8-trimethylquinoline, also known by its CAS registry number CAS No. 139719-24-7, is a significant compound in the field of organic chemistry. This compound belongs to the class of quinolines, which are heterocyclic aromatic compounds with a nitrogen atom in the ring structure. The presence of chlorine and methyl groups at specific positions on the quinoline ring imparts unique chemical properties and reactivity to this compound.

The structural characterization of 2-chloro-4,6,8-trimethylquinoline reveals a rigid aromatic system with substituents at positions 2 (chlorine), 4, 6, and 8 (methyl groups). This substitution pattern is critical in determining its electronic properties and reactivity. Recent studies have highlighted the potential of this compound in various applications, including drug discovery and materials science.

In terms of synthesis, 2-chloro-4,6,8-trimethylquinoline can be prepared through a variety of methods. One common approach involves the Friedlander synthesis pathway, which typically employs an o-amino aryl ketone as a precursor. The reaction conditions and choice of reagents play a pivotal role in achieving high yields and purity of the final product. Researchers have explored alternative synthetic routes to optimize the process further.

The electronic properties of 2-chloro-4,6,8-trimethylquinoline make it an attractive candidate for use in organic electronics. Its conjugated π-system facilitates electron delocalization and enhances electrical conductivity. Recent advancements in materials science have demonstrated its potential as a component in organic semiconductors and light-emitting diodes (OLEDs). These applications underscore its importance in modern technological innovations.

In the field of pharmacology, 2-chloro-4,6,8-trimethylquinoline has shown promise as a lead compound for drug development. Its ability to interact with specific biological targets has been explored in various disease models. For instance, studies have indicated potential anti-inflammatory and anticancer activities associated with this compound. Further research is ongoing to elucidate its mechanism of action and optimize its therapeutic profile.

The environmental impact and degradation pathways of CAS No. 139719-24-7 are also areas of interest for researchers. Understanding how this compound behaves in different environmental conditions is crucial for assessing its safety and sustainability. Recent studies have focused on biodegradation processes and the influence of environmental factors on its stability.

In conclusion, 2-chloro-4,6,8-trimethylquinoline, with its unique chemical structure and versatile properties, continues to be a subject of intense research across multiple disciplines. Its applications span from organic electronics to pharmacology, making it a valuable compound in both academic and industrial settings.

• 634-47-9(2-chloro-4-methyl-quinoline)
• 3913-17-5(2-Chloro-4,8-dimethylquinoline)
• 61773-06-6(Benzo[h]quinoline, 2-chloro-4-methyl-)
• 948291-54-1(2,6-dichloro-3,8-dimethyl-quinoline)
• 139719-23-6(2-Chloro-6,8-dimethylquinoline)
• 88499-92-7(2-chloro-4,7-dimethylquinoline)
• 61773-05-5(Benzo[f]quinoline, 3-chloro-1-methyl-)
• 4225-85-8(2-Chloro-8-methylquinoline)
• 3913-18-6(2-Chloro-4,6-dimethylquinoline)
• 90723-71-0(2,6-Dichloro-4-methylquinoline)