Cas no 1396123-92-4 (1-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-5-trifluoromethyl-1H-pyrazole)

1-Methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-5-trifluoromethyl-1H-pyrazole is a boronic ester derivative of a trifluoromethyl-substituted pyrazole, serving as a versatile intermediate in organic synthesis, particularly in Suzuki-Miyaura cross-coupling reactions. The presence of the dioxaborolane group enhances stability and handling, while the trifluoromethyl moiety imparts unique electronic and steric properties, making it valuable for pharmaceutical and agrochemical applications. Its well-defined structure ensures consistent reactivity, facilitating the construction of complex heterocyclic frameworks. The compound is typically used under inert conditions to preserve its boronate functionality. Suitable for research and industrial-scale applications, it offers a reliable route to fluorinated pyrazole derivatives with high selectivity.
1-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-5-trifluoromethyl-1H-pyrazole structure
1396123-92-4 structure
Product Name:1-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-5-trifluoromethyl-1H-pyrazole
CAS No:1396123-92-4
MF:C11H16BF3N2O2
MW:276.063153266907
CID:5208873
PubChem ID:130702833
Update Time:2026-03-06

1-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-5-trifluoromethyl-1H-pyrazole Chemical and Physical Properties

Names and Identifiers

    • 1-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-5-trifluoromethyl-1H-pyrazole
    • 1H-Pyrazole, 1-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-5-(trifluoromethyl)-
    • 1-Methyl-5-(trifluoromethyl)pyrazole-3-boronic Acid Pinacol Ester
    • 1-methyl-3-(tetramethyl-1,3,2-dioxaborolan-2-yl)-5-(trifluoromethyl)-1H-pyrazole
    • SY291212
    • 1-Methyl-5-(trifluoromethyl)-1H-pyrazole-3-boronic acid, pinacol ester
    • EN300-6286064
    • F86634
    • 1-Methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-5-(trifluoromethyl)-1H-pyrazole
    • Z2217314697
    • MFCD28368565
    • 1-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-5-(trifluoromethyl)pyrazole
    • RS-2187
    • 1396123-92-4
    • 1-Methyl-5-(trifluoromethyl)-1H-pyrazole-3-boronicacid,pinacolester
    • Inchi： 1S/C11H16BF3N2O2/c1-9(2)10(3,4)19-12(18-9)8-6-7(11(13,14)15)17(5)16-8/h6H,1-5H3
    • InChI Key： QHRFKHQXQWMDRW-UHFFFAOYSA-N
    • SMILES： N1(C)C(C(F)(F)F)=CC(B2OC(C)(C)C(C)(C)O2)=N1

Computed Properties

  • Exact Mass: 276.1256924g/mol
  • Monoisotopic Mass: 276.1256924g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 6
  • Heavy Atom Count: 19
  • Rotatable Bond Count: 1
  • Complexity: 346
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 36.3?2

1-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-5-trifluoromethyl-1H-pyrazole Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
Apollo Scientific
PC512023-50mg
1-Methyl-5-(trifluoromethyl)-1H-pyrazole-3-boronic acid, pinacol ester
 1396123-92-4
50mg
 ￡175.00 2025-02-21
Apollo Scientific
PC512023-100mg
1-Methyl-5-(trifluoromethyl)-1H-pyrazole-3-boronic acid, pinacol ester
 1396123-92-4
100mg
 ￡320.00 2025-02-21
Apollo Scientific
PC512023-250mg
1-Methyl-5-(trifluoromethyl)-1H-pyrazole-3-boronic acid, pinacol ester
 1396123-92-4
250mg
￡640.00 2022-03-29
Enamine
EN300-6286064-0.05g
1-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-5-(trifluoromethyl)-1H-pyrazole
 1396123-92-4 95.0%
0.05g
 $537.0 2025-03-15
Enamine
EN300-6286064-0.1g
1-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-5-(trifluoromethyl)-1H-pyrazole
 1396123-92-4 95.0%
0.1g
 $701.0 2025-03-15
Enamine
EN300-6286064-0.25g
1-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-5-(trifluoromethyl)-1H-pyrazole
 1396123-92-4 95.0%
0.25g
 $999.0 2025-03-15
Enamine
EN300-6286064-0.5g
1-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-5-(trifluoromethyl)-1H-pyrazole
 1396123-92-4 95.0%
0.5g
 $1574.0 2025-03-15
Enamine
EN300-6286064-1.0g
1-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-5-(trifluoromethyl)-1H-pyrazole
 1396123-92-4 95.0%
1.0g
 $2019.0 2025-03-15
Enamine
EN300-6286064-2.5g
1-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-5-(trifluoromethyl)-1H-pyrazole
 1396123-92-4 95.0%
2.5g
 $3957.0 2025-03-15
Enamine
EN300-6286064-5.0g
1-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-5-(trifluoromethyl)-1H-pyrazole
 1396123-92-4 95.0%
5.0g
 $5854.0 2025-03-15

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