Cas no 1384428-34-5 (1-{4-(difluoromethyl)sulfanylphenyl}ethan-1-amine hydrochloride)
1-{4-(Difluoromethyl)sulfanylphenyl}ethan-1-amine hydrochloride is a fluorinated organic compound featuring a difluoromethylthio (-SCF2H) substituent on the phenyl ring, coupled with an ethylamine hydrochloride moiety. The difluoromethylthio group enhances metabolic stability and lipophilicity, potentially improving bioavailability and membrane permeability in pharmaceutical applications. The hydrochloride salt form ensures improved solubility and crystallinity, facilitating handling and formulation. This compound may serve as a versatile intermediate in medicinal chemistry, particularly for the development of bioactive molecules targeting CNS disorders or enzyme modulation. Its structural features, including the electron-withdrawing SCF2H group, could also contribute to unique reactivity in synthetic transformations. The compound's purity and stability are critical for reproducible research and scalable synthesis.
1384428-34-5 structure
Product Name:1-{4-(difluoromethyl)sulfanylphenyl}ethan-1-amine hydrochloride
CAS No:1384428-34-5
MF:C9H12ClF2NS
MW:239.713087081909
CID:4595841
PubChem ID:71755431
Update Time:2025-07-02
1-{4-(difluoromethyl)sulfanylphenyl}ethan-1-amine hydrochloride Chemical and Physical Properties
Names and Identifiers
-
- 1-{4-[(difluoromethyl)sulfanyl]phenyl}ethan-1-amine hydrochloride
- 1-{4-(difluoromethyl)sulfanylphenyl}ethan-1-amine hydrochloride
-
- Inchi: 1S/C9H11F2NS.ClH/c1-6(12)7-2-4-8(5-3-7)13-9(10)11;/h2-6,9H,12H2,1H3;1H
- InChI Key: DUEXLUMMSYLXCU-UHFFFAOYSA-N
- SMILES: S(C1C=CC(C(N)C)=CC=1)C(F)F.Cl
Experimental Properties
- Melting Point: NA
1-{4-(difluoromethyl)sulfanylphenyl}ethan-1-amine hydrochloride Security Information
- Signal Word:warning
- Hazard Statement: H303May be harmful if swallowed+H313Skin contact may be harmful+H333Inhalation may be harmful to the body
- Warning Statement: P264+P280+P305+P351+P338+P337+P313
- Safety Instruction: H303+H313+H333
- Storage Condition:storage at -4℃ (1-2weeks), longer storage period at -20℃ (1-2years)
1-{4-(difluoromethyl)sulfanylphenyl}ethan-1-amine hydrochloride Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| TRC | D261005-5mg |
1-{4-[(difluoromethyl)sulfanyl]phenyl}ethan-1-amine hydrochloride |
1384428-34-5 | 5mg |
$ 50.00 | 2022-06-05 | ||
| TRC | D261005-10mg |
1-{4-[(difluoromethyl)sulfanyl]phenyl}ethan-1-amine hydrochloride |
1384428-34-5 | 10mg |
$ 70.00 | 2022-06-05 | ||
| TRC | D261005-50mg |
1-{4-[(difluoromethyl)sulfanyl]phenyl}ethan-1-amine hydrochloride |
1384428-34-5 | 50mg |
$ 295.00 | 2022-06-05 | ||
| Enamine | EN300-100528-0.05g |
1-{4-[(difluoromethyl)sulfanyl]phenyl}ethan-1-amine hydrochloride |
1384428-34-5 | 95% | 0.05g |
$229.0 | 2023-10-28 | |
| Enamine | EN300-100528-0.1g |
1-{4-[(difluoromethyl)sulfanyl]phenyl}ethan-1-amine hydrochloride |
1384428-34-5 | 95% | 0.1g |
$342.0 | 2023-10-28 | |
| Enamine | EN300-100528-0.25g |
1-{4-[(difluoromethyl)sulfanyl]phenyl}ethan-1-amine hydrochloride |
1384428-34-5 | 95% | 0.25g |
$487.0 | 2023-10-28 | |
| Enamine | EN300-100528-0.5g |
1-{4-[(difluoromethyl)sulfanyl]phenyl}ethan-1-amine hydrochloride |
1384428-34-5 | 95% | 0.5g |
$768.0 | 2023-10-28 | |
| Enamine | EN300-100528-1.0g |
1-{4-[(difluoromethyl)sulfanyl]phenyl}ethan-1-amine hydrochloride |
1384428-34-5 | 95% | 1g |
$986.0 | 2023-06-10 | |
| Enamine | EN300-100528-2.5g |
1-{4-[(difluoromethyl)sulfanyl]phenyl}ethan-1-amine hydrochloride |
1384428-34-5 | 95% | 2.5g |
$1931.0 | 2023-10-28 | |
| Enamine | EN300-100528-5.0g |
1-{4-[(difluoromethyl)sulfanyl]phenyl}ethan-1-amine hydrochloride |
1384428-34-5 | 95% | 5g |
$2858.0 | 2023-06-10 |
1-{4-(difluoromethyl)sulfanylphenyl}ethan-1-amine hydrochloride Related Literature
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Domenico Lombardo,Gianmarco Munaò,Pietro Calandra,Luigi Pasqua,Maria Teresa Caccamo Phys. Chem. Chem. Phys., 2019,21, 11983-11991
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2. Fatty acid eutectic mixtures and derivatives from non-edible animal fat as phase change materials?Pau Gallart-Sirvent,Marc Martín,Gemma Villorbina,Mercè Balcells,Aran Solé,Luisa F. Cabeza,Ramon Canela-Garayoa RSC Adv., 2017,7, 24133-24139
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Hanie Hashtroudi,Ian D. R. Mackinnon J. Mater. Chem. C, 2020,8, 13108-13126
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Jason Y. C. Lim,Yong Yu,Guorui Jin,Kai Li,Yi Lu,Jianping Xie Nanoscale Adv., 2020,2, 3921-3932
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