• 1. Establishing plasmon contribution to chemical reactions: alkoxyamines as a thermal probe?
  Olga Guselnikova,Gérard Audran,Jean-Patrick Joly,Andrii Trelin,Evgeny V. Tretyakov,Vaclav Svorcik,Oleksiy Lyutakov,Sylvain R. A. Marque Chem. Sci., 2021,12, 4154-4161
• 2. Evidence of CO2 molecule acting as an electron acceptor on a nanoporous metal–organic-framework MIL-53 or Cr3+(OH)(O2C–C6H4–CO2)?
  Alexandre Vimont,Arnaud Travert,Philippe Bazin,Jean-Claude Lavalley,Marco Daturi,Christian Serre,Gérard Férey,Sandrine Bourrelly,Philip L. Llewellyn Chem. Commun., 2007, 3291-3293
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  Xing Zhao,Lu Bai,Rui-Ying Bao,Zheng-Ying Liu,Ming-Bo Yang,Wei Yang RSC Adv., 2017,7, 46297-46305
• 5. Evidence for the intrinsic nature of band-gap states electrochemically observed on atomically flat TiO2(110) surfaces?
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• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Pyridines and derivatives Pyridine carboxaldehydes

Comprehensive Overview of 5-Bromo-6-methylpyridine-2-carbaldehyde (CAS No. 137778-18-8)

5-Bromo-6-methylpyridine-2-carbaldehyde (CAS No. 137778-18-8) is a highly versatile heterocyclic aldehyde that has garnered significant attention in pharmaceutical and agrochemical research. This compound, characterized by its brominated pyridine core and aldehyde functional group, serves as a critical intermediate in the synthesis of various bioactive molecules. Its unique structural features make it invaluable for drug discovery, material science, and catalysis. Researchers are particularly interested in its potential applications in medicinal chemistry, where it is used to develop novel kinase inhibitors and antiviral agents.

The growing demand for 5-Bromo-6-methylpyridine-2-carbaldehyde is driven by its role in constructing complex organic frameworks. Its reactive aldehyde group allows for facile derivatization, enabling the creation of high-value intermediates for pharmaceuticals. Recent studies highlight its utility in palladium-catalyzed cross-coupling reactions, a hot topic in green chemistry and sustainable synthesis. This aligns with the increasing focus on eco-friendly chemical processes, a trend frequently searched by users in AI-driven research tools and scientific databases.

In the context of user search trends, queries such as "5-Bromo-6-methylpyridine-2-carbaldehyde synthesis" and "CAS 137778-18-8 applications" are prevalent. These reflect the compound's relevance in academic and industrial settings. Additionally, its potential in cancer research and neurodegenerative disease therapeutics has sparked interest, as evidenced by rising searches for "pyridine derivatives in drug development." The compound's structural adaptability makes it a focal point for high-throughput screening and computational chemistry studies.

From a technical standpoint, 5-Bromo-6-methylpyridine-2-carbaldehyde exhibits excellent stability under standard conditions, making it suitable for long-term storage and large-scale production. Its spectroscopic properties, including distinct NMR peaks and IR absorption bands, facilitate easy identification and purity assessment. These attributes are crucial for quality control in GMP-compliant manufacturing, a topic frequently explored in regulatory chemistry forums.

Looking ahead, the compound's integration into cutting-edge technologies like flow chemistry and machine learning-assisted synthesis positions it as a future-proof building block. As the scientific community prioritizes efficient synthetic routes and atom economy, 5-Bromo-6-methylpyridine-2-carbaldehyde stands out as a key enabler of innovation. Its compatibility with bioconjugation techniques further expands its utility in diagnostic reagent development, addressing another high-traffic search area in life sciences.

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• 408359-07-9(3-Bromo-1H-pyrrole-2-carbaldehyde)
• 898559-25-6(3,5-Dibromopyridine-2-carbaldehyde)
• 898559-24-5(3-Bromoquinoline-2-carbaldehyde)
• 1289031-61-3(4,5-dibromopicolinaldehyde)
• 405174-97-2(3-bromopyridine-2-carbaldehyde)
• 31181-90-5(5-Bromopyridine-2-carbaldehyde)
• 3430-31-7(3-Bromo-2,6-dimethylpyridine)
• 886364-94-9(5-Bromo-4-methylpicolinaldehyde)