Cas no 1374572-67-4 (5-bromo-4-(trifluoromethyl)-1,3-dihydro-2-benzofuran-1-one)
5-Bromo-4-(trifluoromethyl)-1,3-dihydro-2-benzofuran-1-one is a halogenated benzofuranone derivative with a trifluoromethyl substituent, offering unique reactivity and stability for synthetic applications. The bromo and trifluoromethyl groups enhance its utility as a versatile intermediate in pharmaceutical and agrochemical synthesis, enabling selective functionalization. Its rigid benzofuranone scaffold provides structural diversity for designing bioactive compounds. The electron-withdrawing trifluoromethyl group improves metabolic stability and lipophilicity, making it valuable in medicinal chemistry. This compound is particularly useful in cross-coupling reactions and as a precursor for heterocyclic frameworks. High purity and well-defined reactivity ensure consistent performance in research and industrial applications.
1374572-67-4 structure
Product Name:5-bromo-4-(trifluoromethyl)-1,3-dihydro-2-benzofuran-1-one
CAS No:1374572-67-4
MF:C9H4BrF3O2
MW:281.026072502136
MDL:MFCD26401727
CID:2124820
PubChem ID:67515653
Update Time:2025-06-07
5-bromo-4-(trifluoromethyl)-1,3-dihydro-2-benzofuran-1-one Chemical and Physical Properties
Names and Identifiers
-
- 5-bromo-4-(trifluoromethyl)isobenzofuran-1(3H)-one
- 1(3H)-Isobenzofuranone, 5-bromo-4-(trifluoromethyl)-
- SXIXTBZVXWZFMI-UHFFFAOYSA-N
- 5-bromo-4-(trifluoromethyl)-2-benzofuran-1(3H)-one
- 5-bromo-4-(trifluoromethyl)-1,3-dihydro-2-benzofuran-1-one
-
- MDL： MFCD26401727
- Inchi： 1S/C9H4BrF3O2/c10-6-2-1-4-5(3-15-8(4)14)7(6)9(11,12)13/h1-2H,3H2
- InChI Key： SXIXTBZVXWZFMI-UHFFFAOYSA-N
- SMILES： BrC1C=CC2C(=O)OCC=2C=1C(F)(F)F
Computed Properties
- Hydrogen Bond Donor Count: 0
- Hydrogen Bond Acceptor Count: 5
- Heavy Atom Count: 15
- Rotatable Bond Count: 0
- Complexity: 279
- Topological Polar Surface Area: 26.3
5-bromo-4-(trifluoromethyl)-1,3-dihydro-2-benzofuran-1-one Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Enamine | EN300-9842501-0.05g |
5-bromo-4-(trifluoromethyl)-1,3-dihydro-2-benzofuran-1-one |
1374572-67-4 | 95.0% | 0.05g |
$484.0 | 2025-02-21 | |
| Enamine | EN300-9842501-0.1g |
5-bromo-4-(trifluoromethyl)-1,3-dihydro-2-benzofuran-1-one |
1374572-67-4 | 95.0% | 0.1g |
$633.0 | 2025-02-21 | |
| Enamine | EN300-9842501-0.25g |
5-bromo-4-(trifluoromethyl)-1,3-dihydro-2-benzofuran-1-one |
1374572-67-4 | 95.0% | 0.25g |
$905.0 | 2025-02-21 | |
| Enamine | EN300-9842501-0.5g |
5-bromo-4-(trifluoromethyl)-1,3-dihydro-2-benzofuran-1-one |
1374572-67-4 | 95.0% | 0.5g |
$1428.0 | 2025-02-21 | |
| Enamine | EN300-9842501-1.0g |
5-bromo-4-(trifluoromethyl)-1,3-dihydro-2-benzofuran-1-one |
1374572-67-4 | 95.0% | 1.0g |
$1829.0 | 2025-02-21 | |
| Enamine | EN300-9842501-2.5g |
5-bromo-4-(trifluoromethyl)-1,3-dihydro-2-benzofuran-1-one |
1374572-67-4 | 95.0% | 2.5g |
$3585.0 | 2025-02-21 | |
| Enamine | EN300-9842501-5.0g |
5-bromo-4-(trifluoromethyl)-1,3-dihydro-2-benzofuran-1-one |
1374572-67-4 | 95.0% | 5.0g |
$5304.0 | 2025-02-21 | |
| Enamine | EN300-9842501-10.0g |
5-bromo-4-(trifluoromethyl)-1,3-dihydro-2-benzofuran-1-one |
1374572-67-4 | 95.0% | 10.0g |
$7866.0 | 2025-02-21 | |
| Enamine | EN300-9842501-1g |
5-bromo-4-(trifluoromethyl)-1,3-dihydro-2-benzofuran-1-one |
1374572-67-4 | 95% | 1g |
$1829.0 | 2023-09-01 | |
| Enamine | EN300-9842501-5g |
5-bromo-4-(trifluoromethyl)-1,3-dihydro-2-benzofuran-1-one |
1374572-67-4 | 95% | 5g |
$5304.0 | 2023-09-01 |
5-bromo-4-(trifluoromethyl)-1,3-dihydro-2-benzofuran-1-one Related Literature
-
Andreas Nenning,Manuel Holzmann,Jürgen Fleig,Alexander K. Opitz Mater. Adv., 2021,2, 5422-5431
-
Tao Wang,Yangyang Liu,Yue Deng,Hongbo Fu,Jianmin Chen Environ. Sci.: Nano, 2018,5, 1821-1833
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Dhirendra K. Chaudhary,Pramendra Kumar,Lokendra Kumar RSC Adv., 2016,6, 94731-94738
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Erika A. Cobar,Paul R. Horn,Robert G. Bergman,Martin Head-Gordon Phys. Chem. Chem. Phys., 2012,14, 15328-15339
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