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  Doug Ogrin,Laura H. van Poppel,Simon G. Bott,Andrew R. Barron Dalton Trans., 2004, 3689-3694
• 2. An all-solid-state asymmetric device based on a polyaniline hydrogel for a high energy flexible supercapacitor?
  Hamid Heydari,Mohammad B. Gholivand New J. Chem., 2017,41, 237-244
• 3. An approach for correlating the structural and electrical properties of Zr4+-modified SrBi4Ti4O15/SBT ceramic
  Priyambada Nayak,Tanmaya Badapanda,Anil Kumar Singh,Simanchalo Panigrahi RSC Adv., 2017,7, 16319-16331
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  Yi-Bin Ruan,Alexis Depauw,Isabelle Leray Org. Biomol. Chem., 2014,12, 4335-4341
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• Solvents and Organic Chemicals Organic Compounds Organic acids and derivatives Organic carbonic acids and derivatives Organic carbonic acids and derivatives
• Solvents and Organic Chemicals Organic Compounds Organic acids and derivatives Organic carbonic acids and derivatives

N,N-Dichlorourethane (CAS No. 13698-16-3): An Overview of Its Properties, Applications, and Recent Research

N,N-Dichlorourethane (CAS No. 13698-16-3) is a versatile compound with a wide range of applications in the chemical and pharmaceutical industries. This compound, also known as dichloromethyl carbamate, is a colorless liquid with a characteristic odor. Its molecular formula is C₃H₄Cl₂O₂, and it has a molecular weight of approximately 147.96 g/mol. The compound is primarily used as an intermediate in the synthesis of various chemicals and pharmaceuticals.

The physical and chemical properties of N,N-Dichlorourethane are well-documented in the scientific literature. It has a boiling point of around 175°C and a melting point of -55°C. The compound is soluble in most organic solvents but has limited solubility in water. Its density is approximately 1.40 g/cm3 at room temperature. These properties make it suitable for use in various chemical processes, particularly those requiring solubility in organic media.

In the pharmaceutical industry, N,N-Dichlorourethane is used as an intermediate in the synthesis of drugs and other active pharmaceutical ingredients (APIs). Its reactivity and functional groups allow it to participate in a variety of chemical reactions, making it a valuable building block in drug development. Recent research has focused on optimizing the synthesis routes for N,N-Dichlorourethane to improve yield and reduce environmental impact.

A study published in the Journal of Organic Chemistry in 2022 explored the use of green chemistry principles to synthesize N,N-Dichlorourethane. The researchers developed a novel catalytic system that significantly reduced the formation of by-products and minimized waste generation. This approach not only enhances the efficiency of the synthesis process but also aligns with the growing demand for sustainable chemical practices.

In addition to its role as an intermediate, N,N-Dichlorourethane has been investigated for its potential applications in materials science. A recent study published in Advanced Materials reported the use of N,N-Dichlorourethane as a cross-linking agent in polymer synthesis. The researchers found that incorporating N,N-Dichlorourethane into polymer chains improved the mechanical properties and thermal stability of the resulting materials. This finding opens up new possibilities for using N,N-Dichlorourethane in advanced materials for various industrial applications.

The safety profile of N,N-Dichlorourethane is an important consideration for its use in industrial processes. While it is generally considered safe when handled properly, appropriate precautions should be taken to avoid inhalation, ingestion, or skin contact. Safety data sheets (SDS) provide detailed information on handling, storage, and disposal procedures to ensure safe use.

In conclusion, N,N-Dichlorourethane (CAS No. 13698-16-3) is a valuable compound with diverse applications in the chemical and pharmaceutical industries. Its unique properties make it an essential intermediate in drug synthesis and a promising material for advanced applications. Ongoing research continues to explore new uses and more efficient synthesis methods, further solidifying its importance in modern chemistry.

• 73506-73-7(Carbamic-14C acid,ethyl ester (9CI))
• 26680-22-8(Ethyl carbamate homopolymer)
• 1616-88-2(Ethanol, 2-methoxy-,1-carbamate)
• 5395-01-7(2-Hydroxyethyl carbamate)
• 19150-42-6(ethane-1,2-diyl dicarbamate)
• 4341-20-2( )
• 54662-02-1(Hydrazinecarboxylic acid, propyl ester)
• 4114-31-2(Ethyl carbazate)
• 73962-07-9(Urethane-d)
• 51-79-6(Urethane)