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• 2. An aptamer-based keypad lock system?
  Yaqing Liu,Jiangtao Ren,Jing Li,Jiyang Liu,Erkang Wang Chem. Commun., 2012,48, 802-804
• 3. An ionic liquid promoted microwave-hydrothermal route towards highly photoluminescent carbon dots for sensitive and selective detection of iron(iii)?
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• Solvents and Organic Chemicals Organic Compounds Organic nitrogen compounds Organonitrogen compounds Aralkylamines
• Solvents and Organic Chemicals Organic Compounds Organic nitrogen compounds Organonitrogen compounds Amines Aralkylamines

N-(4-AMINOPHENYL)-N-CYCLOHEXYLAMINE (CAS No. 13663-13-3): Properties, Applications, and Market Insights

N-(4-Aminophenyl)-N-cyclohexylamine (CAS No. 13663-13-3) is a specialized organic compound with a unique molecular structure that combines an aromatic amine group with a cyclohexyl moiety. This chemical entity has garnered significant attention in recent years due to its versatile applications in pharmaceuticals, agrochemicals, and material science. The compound's dual functionality makes it particularly valuable as an intermediate in synthetic chemistry, where researchers are increasingly exploring its potential in drug discovery and advanced material development.

The molecular structure of N-(4-aminophenyl)-N-cyclohexylamine features a primary aromatic amine group attached to a secondary amine with a cyclohexyl substituent. This configuration provides interesting electronic properties that have become relevant in current research on organic semiconductors and photovoltaic materials. Recent studies published in journals like ACS Applied Materials & Interfaces have highlighted similar compounds for their potential in next-generation electronics, making this chemical particularly interesting for researchers working on sustainable energy solutions.

In pharmaceutical applications, N-(4-aminophenyl)-N-cyclohexylamine derivatives have shown promise in the development of central nervous system (CNS) drugs. The compound's ability to cross the blood-brain barrier makes it a valuable scaffold for neurologically active compounds. Current market trends indicate growing demand for such intermediates as pharmaceutical companies invest more in neurodegenerative disease research and psychiatric medication development. This aligns with increasing public interest in mental health treatments and cognitive enhancers.

The synthesis of CAS 13663-13-3 typically involves the reaction between 4-nitroaniline and cyclohexylamine, followed by reduction of the nitro group. Recent advancements in green chemistry have led to more sustainable production methods, addressing environmental concerns in chemical manufacturing. These developments respond to growing consumer demand for eco-friendly chemicals and industry movements toward sustainable practices, which are frequently searched topics in scientific and industrial communities.

Material scientists have discovered that N-(4-aminophenyl)-N-cyclohexylamine can serve as a building block for conjugated polymers with interesting optoelectronic properties. This application has gained traction in the development of organic light-emitting diodes (OLEDs) and flexible electronics - two areas experiencing rapid growth due to the expansion of wearable technology and foldable devices in consumer electronics markets.

Quality control of N-(4-aminophenyl)-N-cyclohexylamine typically involves HPLC analysis and spectroscopic characterization to ensure purity levels suitable for various applications. The compound's stability under different conditions makes it particularly valuable for industrial applications where long-term storage and thermal stability are important considerations. These properties are frequently queried by quality assurance professionals and procurement specialists in chemical supply chains.

Market analysis indicates steady growth in demand for CAS 13663-13-3, particularly from the Asia-Pacific region where pharmaceutical and electronics manufacturing are expanding rapidly. Suppliers are increasingly focusing on providing high-purity grades of this compound to meet the stringent requirements of these industries. The global market for similar amine derivatives is projected to grow at a CAGR of 5-7% over the next five years, according to recent chemical industry reports.

Researchers working with N-(4-aminophenyl)-N-cyclohexylamine should be aware of its solubility characteristics - it's typically soluble in common organic solvents like ethanol, methanol, and dichloromethane, but has limited water solubility. This information is crucial for formulators and process chemists who frequently search for solubility data and formulation guidance when working with similar compounds.

The compound's structure-activity relationship has made it a subject of interest in computational chemistry studies, where researchers use molecular modeling to predict its behavior in various systems. This application aligns with current trends in AI-assisted drug discovery and in silico screening - topics generating significant interest in both academic and industrial research communities.

As regulatory requirements for chemical substances become more stringent worldwide, proper documentation and safety data sheets for N-(4-aminophenyl)-N-cyclohexylamine have become increasingly important. Suppliers are now providing more comprehensive technical information to meet these requirements, addressing common queries from EHS (environmental, health, and safety) professionals about chemical handling and regulatory compliance.

In conclusion, N-(4-aminophenyl)-N-cyclohexylamine (CAS No. 13663-13-3) represents an important intermediate with diverse applications across multiple industries. Its unique chemical properties and growing range of applications position it as a compound of continuing interest in both research and industrial settings. The development of novel derivatives and applications for this chemical is likely to remain an active area of investigation, particularly in fields related to advanced materials and pharmaceutical development.

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