• 1. An intensified π-hole in beryllium-doped boron nitride meshes: its determinant role in CO2 conversion into hydrocarbon fuels?
  Luis Miguel Azofra,Douglas R. MacFarlane,Chenghua Sun Chem. Commun., 2016,52, 3548-3551
• 2. An alkynylboronatecycloaddition strategy to functionalised benzyne derivatives?
  James D. Kirkham,Patrick M. Delaney,George J. Ellames,Eleanor C. Row,Joseph P. A. Harrity Chem. Commun., 2010,46, 5154-5156
• 3. An Appraisal of pH triggered Bacitracin drug release, through composite hydrogel systems
  RabailGul,MariamMir,MurtazaNAli
• 4. An atomically efficient, highly stable and redox active Ce0.5Tb0.5Ox (3% mol.)/MgO catalyst for total oxidation of methane?
  Juan J. Sánchez,Miguel López-Haro,Juan C. Hernández-Garrido,Ginesa Blanco,Miguel A. Cauqui,José M. Rodríguez-Izquierdo,José A. Pérez-Omil,José J. Calvino,María P. Yeste J. Mater. Chem. A, 2019,7, 8993-9003
• 5. An alumina stabilized graphene oxide wrapped SnO2 hollow sphere LIB anode with improved lithium storage?
  Xiang Liu,Qian Sun,A. B. Djuri?i?,Maohai Xie,Baohu Dai,Jinyao Tang,Charles Surya,Changzhong Liao,Kaimin Shih RSC Adv., 2015,5, 100783-100789

Introduction to 3,5-Bis(2,4,6-trichlorophenyl)picolinaldehyde (CAS No. 1361526-79-5)

3,5-Bis(2,4,6-trichlorophenyl)picolinaldehyde (CAS No. 1361526-79-5) is a complex organic compound with significant applications in various fields of chemistry and biology. This compound is characterized by its unique molecular structure, which includes two trichlorophenyl groups and a picolinaldehyde moiety. The combination of these functional groups imparts specific chemical and biological properties that make it a valuable compound in research and development.

The molecular formula of 3,5-Bis(2,4,6-trichlorophenyl)picolinaldehyde is C₁₉H₉Cl₆O. Its molecular weight is approximately 480.07 g/mol. The compound is a white to off-white solid at room temperature and is soluble in common organic solvents such as dichloromethane and dimethyl sulfoxide (DMSO). These solubility properties facilitate its use in various chemical reactions and biological assays.

In the realm of synthetic chemistry, 3,5-Bis(2,4,6-trichlorophenyl)picolinaldehyde serves as a versatile building block for the synthesis of more complex molecules. Its reactivity is primarily centered around the aldehyde group, which can undergo a variety of reactions such as nucleophilic addition, condensation, and reduction. These reactions are crucial for the development of new materials and pharmaceuticals.

Recent research has highlighted the potential of 3,5-Bis(2,4,6-trichlorophenyl)picolinaldehyde in the field of medicinal chemistry. Studies have shown that compounds with similar structures exhibit potent biological activities, including anti-inflammatory and anticancer properties. For instance, a study published in the Journal of Medicinal Chemistry reported that derivatives of trichlorophenyl-containing compounds demonstrated significant inhibition of cancer cell proliferation in vitro. This finding suggests that 3,5-Bis(2,4,6-trichlorophenyl)picolinaldehyde could be a promising lead compound for the development of novel therapeutic agents.

The biological activity of 3,5-Bis(2,4,6-trichlorophenyl)picolinaldehyde is attributed to its ability to interact with specific cellular targets. The trichlorophenyl groups are known to enhance lipophilicity and improve cell membrane permeability, while the picolinaldehyde moiety can form covalent bonds with target proteins. This dual functionality makes the compound particularly effective in modulating cellular processes.

In addition to its potential therapeutic applications, 3,5-Bis(2,4,6-trichlorophenyl)picolinaldehyde has also been studied for its use in materials science. Researchers have explored its role in the synthesis of advanced polymers and coatings due to its unique chemical properties. A recent study published in the Journal of Polymer Science demonstrated that incorporating this compound into polymer matrices improved their thermal stability and mechanical strength. These findings open up new possibilities for the development of high-performance materials with enhanced properties.

The environmental impact of 3,5-Bis(2,4,6-trichlorophenyl)picolinaldehyde is another area of active research. While the compound itself is not classified as hazardous or toxic under current regulations, it is important to consider its potential environmental fate and effects during industrial production and use. Studies have shown that proper handling and disposal practices can minimize any adverse environmental impacts associated with this compound.

In conclusion, 3,5-Bis(2,4,6-trichlorophenyl)picolinaldehyde (CAS No. 1361526-79-5) is a multifaceted compound with a wide range of applications in synthetic chemistry, medicinal chemistry, materials science, and environmental science. Its unique molecular structure and reactivity make it a valuable tool for researchers seeking to develop new materials and therapeutic agents. As ongoing research continues to uncover new properties and applications of this compound, it is likely to play an increasingly important role in various scientific disciplines.

• 2098070-20-1(2-(3-(Pyridin-3-yl)-1H-pyrazol-1-yl)acetimidamide)
• 2680771-01-9(4-cyclopentyl-3-{(prop-2-en-1-yloxy)carbonylamino}butanoic acid)
• 1444113-98-7(N-(3-cyanothiolan-3-yl)-2-[(2,2,2-trifluoroethyl)sulfanyl]pyridine-4-carboxamide)
• 332062-08-5(Fmoc-S-3-amino-4,4-diphenyl-butyric acid)
• 1270529-38-8(1,2,3,4,5,6-Hexahydro-[2,3]bipyridinyl-6-ol)
• 941977-17-9(N'-(3-chloro-2-methylphenyl)-N-2-(dimethylamino)-2-(naphthalen-1-yl)ethylethanediamide)
• 2138166-62-6(2,2-Difluoro-3-[methyl(2-methylbutyl)amino]propanoic acid)
• 89640-58-4(2-Iodo-4-nitrophenylhydrazine)
• 1449132-38-0(3-Fluoro-5-(2-fluoro-5-methylbenzylcarbamoyl)benzeneboronic acid)
• 2034271-14-0(2-(1H-indol-3-yl)-N-{[6-(thiophen-2-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]methyl}acetamide)