• 1. Evolution of dealloying induced strain in nanoporous gold crystals?
  Ross Harder,David C. Dunand,Ian McNulty Nanoscale, 2017,9, 5686-5693
• 2. Evidence of rutile-to-anatase photo-induced electron transfer in mixed-phase TiO2 by solid-state NMR spectroscopy?
  Weili Dai,Guangjun Wu,Michael Hunger Chem. Commun., 2015,51, 13779-13782
• 3. Estimates of hydride ion stability in condensed systems: energy of formation and solvation in aqueous and polar-organic solvents
  Craig A. Kelly,David R. Rosseinsky Phys. Chem. Chem. Phys., 2001,3, 2086-2090
• 4. Fast-Track to Research Data Management in Experimental Material Science-Setting the Ground for Research Group Level Materials Digitalization.
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• 5. Fe(ii)-Assisted one-pot synthesis of ultra-small core–shell Au–Pt nanoparticles as superior catalysts towards the HER and ORR?
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• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Pyridines and derivatives Halopyridines Polyhalopyridines

2,3-Dichloro-6-hydrazinylpyridine (CAS No. 1361399-75-8): Properties, Applications, and Market Insights

2,3-Dichloro-6-hydrazinylpyridine (CAS No. 1361399-75-8) is a specialized heterocyclic compound with significant potential in pharmaceutical and agrochemical research. This pyridine derivative features a unique combination of chloro and hydrazinyl functional groups, making it a versatile intermediate for synthesizing bioactive molecules. Its molecular formula is C₅H₅Cl₂N₃, and it exhibits a molecular weight of 177.02 g/mol.

The compound's chemical structure consists of a pyridine ring substituted with two chlorine atoms at positions 2 and 3, along with a hydrazinyl group at position 6. This arrangement contributes to its reactivity and utility in organic synthesis. Researchers often explore 2,3-dichloro-6-hydrazinylpyridine derivatives for their potential in drug discovery, particularly in developing antimicrobial agents and enzyme inhibitors.

In recent years, the demand for specialty pyridine compounds like 2,3-dichloro-6-hydrazinylpyridine has grown significantly, driven by advancements in medicinal chemistry and crop protection technologies. The compound's ability to serve as a building block for more complex structures makes it valuable in high-throughput screening programs and structure-activity relationship studies.

From a physicochemical perspective, 2,3-dichloro-6-hydrazinylpyridine typically appears as a white to off-white crystalline powder with moderate solubility in polar organic solvents. Its stability profile makes it suitable for various laboratory applications, though proper storage conditions (typically 2-8°C in airtight containers) are recommended to maintain its integrity over time.

The synthetic applications of CAS 1361399-75-8 are particularly noteworthy. Chemists frequently employ this compound as a precursor for creating pyridine-based scaffolds with potential biological activity. Recent publications have highlighted its use in developing novel heterocyclic compounds with applications ranging from pharmaceutical intermediates to material science components.

Market analysis indicates growing interest in 2,3-dichloro-6-hydrazinylpyridine suppliers and manufacturers, particularly from research institutions and pharmaceutical companies. The compound's niche application spectrum creates opportunities for specialized chemical distributors who can provide high-purity samples with comprehensive analytical documentation.

From a regulatory standpoint, while 2,3-dichloro-6-hydrazinylpyridine is not classified as hazardous under standard chemical safety protocols, researchers should always follow good laboratory practices when handling this material. Proper personal protective equipment (PPE) including gloves and safety glasses is recommended during experimental procedures.

The future outlook for 2,3-dichloro-6-hydrazinylpyridine research appears promising, with several patent applications referencing derivatives of this compound in recent years. Its structural features make it particularly interesting for drug discovery programs targeting infectious diseases and metabolic disorders, aligning with current global health priorities.

For laboratories considering 2,3-dichloro-6-hydrazinylpyridine synthesis or procurement, it's essential to verify the compound's purity through appropriate analytical methods such as HPLC or NMR. Reputable suppliers typically provide certificates of analysis detailing the material's characteristics and impurity profiles.

In conclusion, 2,3-dichloro-6-hydrazinylpyridine (CAS No. 1361399-75-8) represents an important chemical building block with diverse applications in modern chemistry. Its unique structural features and synthetic versatility continue to attract interest from both academic and industrial researchers exploring novel heterocyclic compounds for various scientific and technological applications.

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