Cas no 1356068-62-6 (3-Cyano-2-morpholinopyridine-5-boronic acid, pinacol ester)
3-Cyano-2-morpholinopyridine-5-boronic acid pinacol ester is a high-purity boronic ester derivative commonly employed in Suzuki-Miyaura cross-coupling reactions. The presence of the morpholine and cyano substituents enhances its stability and reactivity, making it a valuable intermediate in pharmaceutical and agrochemical synthesis. The pinacol ester group improves handling and shelf-life by protecting the boronic acid functionality from protodeboronation. This compound is particularly useful in constructing complex heterocyclic frameworks due to its compatibility with a wide range of reaction conditions. Its consistent performance and well-defined structure make it a reliable choice for researchers developing novel bioactive molecules.
1356068-62-6 structure
Product Name:3-Cyano-2-morpholinopyridine-5-boronic acid, pinacol ester
CAS No:1356068-62-6
MF:C16H22BN3O3
MW:315.175183773041
MDL:MFCD16996767
CID:1039304
PubChem ID:53217326
Update Time:2025-06-08
3-Cyano-2-morpholinopyridine-5-boronic acid, pinacol ester Chemical and Physical Properties
Names and Identifiers
-
- 2-Morpholino-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)nicotinonitrile
- 3-Cyano-2-morpholinopyridine-5-boronic acid,pinacol ester
- 3-Cyano-2-morpholinopyridine-5-boronic acid, pinacol ester
- BS-26535
- 2-(Morpholin-4-yl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine-3-carbonitrile
- 1356068-62-6
- AT14376
- A886984
- MB21547
- DTXSID20682387
- CS-0174440
- MFCD16996767
- 2-morpholin-4-yl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine-3-carbonitrile
- 2-(4-Morpholinyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)nicotinonitrile
- DB-085179
- AKOS016001087
-
- MDL： MFCD16996767
- Inchi： 1S/C16H22BN3O3/c1-15(2)16(3,4)23-17(22-15)13-9-12(10-18)14(19-11-13)20-5-7-21-8-6-20/h9,11H,5-8H2,1-4H3
- InChI Key： KMOMTJKORSQJNI-UHFFFAOYSA-N
- SMILES： O1B(C2=CN=C(C(C#N)=C2)N2CCOCC2)OC(C)(C)C1(C)C
Computed Properties
- Exact Mass: 315.17500
- Monoisotopic Mass: 315.175
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 0
- Hydrogen Bond Acceptor Count: 6
- Heavy Atom Count: 23
- Rotatable Bond Count: 2
- Complexity: 468
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Topological Polar Surface Area: 67.6A^2
Experimental Properties
- PSA: 67.61000
- LogP: 1.15408
3-Cyano-2-morpholinopyridine-5-boronic acid, pinacol ester Customs Data
- HS CODE：2934999090
- Customs Data：
China Customs Code:
2934999090Overview:
2934999090. Other heterocyclic compounds. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%
Declaration elements:
Product Name, component content, use to
Summary:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
3-Cyano-2-morpholinopyridine-5-boronic acid, pinacol ester Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Alichem | A449036471-5g |
2-Morpholino-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)nicotinonitrile |
1356068-62-6 | 95% | 5g |
837.90 USD | 2021-06-15 | |
| Chemenu | CM135111-1g |
2-Morpholino-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)nicotinonitrile |
1356068-62-6 | 95% | 1g |
$388 | 2023-02-18 | |
| TRC | C987713-25mg |
3-Cyano-2-morpholinopyridine-5-boronic acid, pinacol ester |
1356068-62-6 | 25mg |
$64.00 | 2023-05-18 | ||
| TRC | C987713-50mg |
3-Cyano-2-morpholinopyridine-5-boronic acid, pinacol ester |
1356068-62-6 | 50mg |
$92.00 | 2023-05-18 | ||
| TRC | C987713-100mg |
3-Cyano-2-morpholinopyridine-5-boronic acid, pinacol ester |
1356068-62-6 | 100mg |
$144.00 | 2023-05-18 | ||
| TRC | C987713-250mg |
3-Cyano-2-morpholinopyridine-5-boronic acid, pinacol ester |
1356068-62-6 | 250mg |
$253.00 | 2023-05-18 | ||
| Fluorochem | 217164-250mg |
2-Morpholino-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)nicotinonitrile |
1356068-62-6 | 95% | 250mg |
￡150.00 | 2022-03-01 | |
| Fluorochem | 217164-1g |
2-Morpholino-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)nicotinonitrile |
1356068-62-6 | 95% | 1g |
￡350.00 | 2022-03-01 | |
| abcr | AB311601-250 mg |
3-Cyano-2-morpholinopyridine-5-boronic acid, pinacol ester; 96% |
1356068-62-6 | 250 mg |
€246.00 | 2023-07-19 | ||
| abcr | AB311601-1 g |
3-Cyano-2-morpholinopyridine-5-boronic acid, pinacol ester; 96% |
1356068-62-6 | 1 g |
€518.00 | 2023-07-19 |
3-Cyano-2-morpholinopyridine-5-boronic acid, pinacol ester Related Literature
-
Ravi Kumar Yadav,R. Govindaraj Phys. Chem. Chem. Phys., 2020,22, 26876-26886
-
Lei Yang,Yuan Zeng,Haibo Wu,Chunwu Zhou,Lei Tao J. Mater. Chem. B, 2020,8, 1383-1388
-
Huabin Zhang,Shaowu Du CrystEngComm, 2014,16, 4059-4068
-
Yu-Nong Li,Liang-Nian He,Xian-Dong Lang,Xiao-Fang Liu,Shuai Zhang RSC Adv., 2014,4, 49995-50002
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