Cas no 1354010-37-9 (tert-butyl (3R)-3-iodopiperidine-1-carboxylate)
Technical Introduction:
tert-Butyl (3R)-3-iodopiperidine-1-carboxylate is a chiral intermediate widely used in organic synthesis and pharmaceutical applications. Its key advantages include high stereochemical purity, making it valuable for asymmetric synthesis and the preparation of biologically active compounds. The tert-butoxycarbonyl (Boc) protecting group enhances stability and facilitates selective deprotection under mild acidic conditions. The iodine substituent at the 3-position offers versatility for further functionalization via cross-coupling or nucleophilic substitution reactions. This compound is particularly useful in the synthesis of piperidine-based scaffolds, which are prevalent in medicinal chemistry. Its well-defined configuration and reactivity make it a reliable building block for complex molecule construction.
1354010-37-9 structure
Product Name:tert-butyl (3R)-3-iodopiperidine-1-carboxylate
CAS No:1354010-37-9
MF:C10H18INO2
MW:311.159895420074
CID:2155314
Update Time:2025-05-27
tert-butyl (3R)-3-iodopiperidine-1-carboxylate Chemical and Physical Properties
Names and Identifiers
-
- (R)-3-iodo-piperidine-1-carboxylic acid tert-butyl ester
- (R)-tert-Butyl 3-iodopiperidine-1-carboxylate
- AM96327
- SB10218
- tert-butyl(3R)-3-iodopiperidine-1-carboxylate
- (R)-3-Iodopiperidine-1-carboxylic acid tert-butyl ester
- TERT-BUTYL (3R)-3-IODOPIPERIDINE-1-CARBOXYLATE
- tert-butyl (3R)-3-iodopiperidine-1-carboxylate
-
- Inchi： 1S/C10H18INO2/c1-10(2,3)14-9(13)12-6-4-5-8(11)7-12/h8H,4-7H2,1-3H3/t8-/m1/s1
- InChI Key： JXEZFSNOYBRXFT-MRVPVSSYSA-N
- SMILES： I[C@H]1CN(C(=O)OC(C)(C)C)CCC1
Computed Properties
- Hydrogen Bond Donor Count: 0
- Hydrogen Bond Acceptor Count: 2
- Heavy Atom Count: 14
- Rotatable Bond Count: 2
- Complexity: 213
- Topological Polar Surface Area: 29.5
Experimental Properties
- Density: 1.5±0.1 g/cm3
- Boiling Point: 318.8±35.0 °C at 760 mmHg
- Flash Point: 146.6±25.9 °C
- Vapor Pressure: 0.0±0.7 mmHg at 25°C
tert-butyl (3R)-3-iodopiperidine-1-carboxylate Security Information
- Signal Word：warning
- Hazard Statement： H303May be harmful if swallowed+H313Skin contact may be harmful+H333Inhalation may be harmful to the body
- Warning Statement： P264+P280+P305+P351+P338+P337+P313
- Safety Instruction： H303+H313+H333
- Storage Condition：storage at -4℃ (1-2weeks), longer storage period at -20℃ (1-2years)
tert-butyl (3R)-3-iodopiperidine-1-carboxylate Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Fluorochem | 087325-1g |
R)-3-Iodo-piperidine-1-carboxylic acid tert-butyl ester |
1354010-37-9 | 1g |
￡945.00 | 2022-03-01 | ||
| Chemenu | CM300806-1g |
(R)-tert-butyl 3-iodopiperidine-1-carboxylate |
1354010-37-9 | 95% | 1g |
$930 | 2021-08-18 | |
| Chemenu | CM300806-1g |
(R)-tert-butyl 3-iodopiperidine-1-carboxylate |
1354010-37-9 | 95% | 1g |
$823 | 2022-09-29 | |
| Ambeed | A266394-1g |
(R)-tert-Butyl 3-iodopiperidine-1-carboxylate |
1354010-37-9 | 98% | 1g |
$831.0 | 2024-04-24 | |
| NAN JING YAO SHI KE JI GU FEN Co., Ltd. | PB00843-100mg |
tert-butyl (3R)-3-iodopiperidine-1-carboxylate |
1354010-37-9 | 95% | 100mg |
￥1413.0 | 2024-04-24 | |
| NAN JING YAO SHI KE JI GU FEN Co., Ltd. | PB00843-250mg |
tert-butyl (3R)-3-iodopiperidine-1-carboxylate |
1354010-37-9 | 95% | 250mg |
￥2255.0 | 2024-04-24 | |
| NAN JING YAO SHI KE JI GU FEN Co., Ltd. | PB00843-500mg |
tert-butyl (3R)-3-iodopiperidine-1-carboxylate |
1354010-37-9 | 95% | 500mg |
￥3758.0 | 2024-04-24 | |
| NAN JING YAO SHI KE JI GU FEN Co., Ltd. | PB00843-1g |
tert-butyl (3R)-3-iodopiperidine-1-carboxylate |
1354010-37-9 | 95% | 1g |
￥5638.0 | 2024-04-24 | |
| NAN JING YAO SHI KE JI GU FEN Co., Ltd. | PB00843-5g |
tert-butyl (3R)-3-iodopiperidine-1-carboxylate |
1354010-37-9 | 95% | 5g |
￥16913.0 | 2024-04-24 | |
| NAN JING YAO SHI KE JI GU FEN Co., Ltd. | PB00843-100.0mg |
tert-butyl (3R)-3-iodopiperidine-1-carboxylate |
1354010-37-9 | 95% | 100.0mg |
￥1413.0000 | 2025-04-12 |
tert-butyl (3R)-3-iodopiperidine-1-carboxylate Related Literature
-
Alexandre Vimont,Arnaud Travert,Philippe Bazin,Jean-Claude Lavalley,Marco Daturi,Christian Serre,Gérard Férey,Sandrine Bourrelly,Philip L. Llewellyn Chem. Commun., 2007, 3291-3293
-
Xing Zhao,Lu Bai,Rui-Ying Bao,Zheng-Ying Liu,Ming-Bo Yang,Wei Yang RSC Adv., 2017,7, 46297-46305
-
Qiyuan Wu,Shangmin Xiong,Peichuan Shen,Shen Zhao,Alexander Orlov Catal. Sci. Technol., 2015,5, 2059-2064
-
Shintaro Takata,Yoshihiro Miura Phys. Chem. Chem. Phys., 2014,16, 24784-24789
-
Norihito Fukui,Keisuke Fujimoto,Hideki Yorimitsu,Atsuhiro Osuka Dalton Trans., 2017,46, 13322-13341
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