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• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Piperidines Piperidines
• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Piperidines

Comprehensive Overview of 2-Chloro-N-ethyl-N-(1-methyl-piperidin-4-ylmethyl)-acetamide (CAS No. 1353959-70-2)

2-Chloro-N-ethyl-N-(1-methyl-piperidin-4-ylmethyl)-acetamide (CAS No. 1353959-70-2) is a specialized organic compound with a unique molecular structure that combines a chloroacetamide backbone with an ethyl and a substituted piperidine moiety. This compound has garnered significant attention in pharmaceutical and chemical research due to its potential applications in drug discovery and development. The presence of the chloroacetamide group and the 1-methyl-piperidin-4-ylmethyl substituent makes it a versatile intermediate for synthesizing bioactive molecules.

The compound’s molecular formula is C₁₁H₂₁ClN₂O, and it exhibits a molecular weight of approximately 232.75 g/mol. Its structure features a chloroacetyl group attached to a nitrogen atom, which is further substituted with an ethyl group and a 1-methyl-piperidin-4-ylmethyl moiety. This arrangement imparts unique physicochemical properties, such as moderate solubility in polar organic solvents and stability under controlled conditions. Researchers often explore its reactivity, particularly in nucleophilic substitution reactions, due to the presence of the chloro functional group.

In recent years, 2-Chloro-N-ethyl-N-(1-methyl-piperidin-4-ylmethyl)-acetamide has been studied for its potential role in medicinal chemistry. Its structural features align with motifs commonly found in central nervous system (CNS) targeting agents, making it a candidate for neuropharmacological applications. The piperidine ring, a prevalent scaffold in drug design, contributes to its bioavailability and interaction with biological targets. This has led to increased interest in its use for developing novel therapeutics, particularly in areas like neurodegenerative diseases and pain management.

The synthesis of 2-Chloro-N-ethyl-N-(1-methyl-piperidin-4-ylmethyl)-acetamide typically involves multi-step organic reactions, including amidation and alkylation processes. High-purity batches are essential for research purposes, and advanced analytical techniques such as HPLC, NMR, and mass spectrometry are employed to ensure quality control. The compound’s stability and purity are critical factors for its utility in laboratory settings, where reproducibility is paramount.

From a commercial perspective, 2-Chloro-N-ethyl-N-(1-methyl-piperidin-4-ylmethyl)-acetamide is available through specialized chemical suppliers catering to pharmaceutical and academic research. Its demand has risen in tandem with the growing focus on small-molecule drug discovery and structure-activity relationship (SAR) studies. Researchers frequently inquire about its availability, pricing, and custom synthesis options, reflecting its niche but significant market presence.

In the context of green chemistry and sustainable practices, efforts are underway to optimize the synthesis of 2-Chloro-N-ethyl-N-(1-methyl-piperidin-4-ylmethyl)-acetamide to minimize waste and energy consumption. Innovations in catalytic methods and solvent selection are being explored to enhance the compound’s accessibility while reducing environmental impact. This aligns with broader industry trends toward eco-friendly chemical production.

Safety and handling guidelines for 2-Chloro-N-ethyl-N-(1-methyl-piperidin-4-ylmethyl)-acetamide emphasize standard laboratory precautions, including the use of personal protective equipment (PPE) and proper ventilation. While not classified as highly hazardous, its chloroacetamide component warrants careful handling to avoid unnecessary exposure. Material Safety Data Sheets (MSDS) provide detailed information on storage, disposal, and emergency measures.

Looking ahead, the potential applications of 2-Chloro-N-ethyl-N-(1-methyl-piperidin-4-ylmethyl)-acetamide are likely to expand as research into its pharmacological properties progresses. Its relevance in drug design and chemical biology underscores its value as a research tool. For scientists and procurement specialists, staying updated on its latest developments and sourcing options is essential to leveraging its full potential.

In summary, 2-Chloro-N-ethyl-N-(1-methyl-piperidin-4-ylmethyl)-acetamide (CAS No. 1353959-70-2) is a compound of growing importance in pharmaceutical and chemical research. Its unique structure, combined with its potential applications in drug discovery, makes it a subject of ongoing investigation. As the scientific community continues to explore its capabilities, this compound is poised to play a pivotal role in advancing medicinal chemistry and molecular innovation.

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