Cas no 13484-66-7 (IST5-002)

IST5-002 structure
IST5-002 structure
Product Name:IST5-002
CAS No:13484-66-7
MF:C17H20N5O7P
MW:437.343764305115
CID:155312
PubChem ID:59310
Update Time:2025-04-24

IST5-002 Chemical and Physical Properties

Names and Identifiers

    • 5'-Adenylic acid,N-(phenylmethyl)-
    • [(2R,3R,4R,5R)-5-[6-(benzylamino)purin-9-yl]-3,4-dihydroxy-oxolan-2-yl ]methoxyphosphonic acid
    • N6-BENZYLADENOSINE-5'-MONOPHOSPHATE SODIUM SALT
    • N6-Benzyladenosine-5'-phosphate
    • 6-N-benzyladenosine-5'-O-monophosphate
    • BAR-5'-monophosphate
    • Benzyl-adenosine monophosphate
    • Benzyl-amp
    • N(6)-Benzyladenosine-5'-monophosphate
    • N6-benzyl-[5']adenylic acid
    • N6-Benzyladenosin-5'-monophosphat
    • N6-Benzyladenosin-5'-phosphat
    • N6-Benzyladenosine 5'-Phosphat
    • Nsc 255523
    • IST5-002
    • N6-Benzyladenosine 5'-monophosphate sodium salt
    • N6–BENZYLADENOSINE-5'-MONOPHOSPHATE SODIUM SALT (BAMP)
    • ((2R,3S,4R,5R)-5-(6-(benzylamino)-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl dihydrogen phosphate
    • CHEMBL519155
    • BDBM50056973
    • CS-0015631
    • 13484-66-7
    • n6-benzyladenosine-5'-monophosphate
    • 5'-Adenylic acid, N-(phenylmethyl)-
    • DWVANBHPEPSMOV-LSCFUAHRSA-N
    • AKOS030488749
    • NSC-255523
    • SCHEMBL218999
    • HY-19527
    • [(2R,3S,4R,5R)-5-[6-(benzylamino)purin-9-yl]-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate
    • DA-51038
    • N6-Benzyladenosine 5'-monophosphate
    • [(2R,3S,4R,5R)-5-[6-(BENZYLAMINO)PURIN-9-YL]-3,4-DIHYDROXYOXOLAN-2-YL]METHOXYPHOSPHONIC ACID
    • Inchi： 1S/C17H20N5O7P/c23-13-11(7-28-30(25,26)27)29-17(14(13)24)22-9-21-12-15(19-8-20-16(12)22)18-6-10-4-2-1-3-5-10/h1-5,8-9,11,13-14,17,23-24H,6-7H2,(H,18,19,20)(H2,25,26,27)/t11-,13-,14-,17-/m1/s1
    • InChI Key： DWVANBHPEPSMOV-LSCFUAHRSA-N
    • SMILES： P(=O)(O)(O)OC[C@@H]1[C@H]([C@H]([C@H](N2C=NC3C(=NC=NC2=3)NCC2C=CC=CC=2)O1)O)O

Computed Properties

  • Exact Mass: 435.09454
  • Monoisotopic Mass: 437.11
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 5
  • Hydrogen Bond Acceptor Count: 11
  • Heavy Atom Count: 30
  • Rotatable Bond Count: 7
  • Complexity: 621
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 4
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: _1.4
  • Topological Polar Surface Area: 172A^2

Experimental Properties

  • Density: 1.81
  • Boiling Point: 798.5°Cat760mmHg
  • Flash Point: 436.7°C
  • PSA: 177.74
  • LogP: 0.23990

IST5-002 Pricemore >>

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IST5-002 Suppliers

NewCan Biotech Limited
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(CAS:13484-66-7)N6-Benzyladenosine 5'-monophosphate sodium salt
Order Number:NC9330
Stock Status:
Quantity:10g
Purity:97%
Pricing Information Last Updated:Friday, 18 July 2025 16:15
Price ($):Price inquiry

IST5-002 Related Literature

Additional information on IST5-002

5'-Adenylic Acid, N-(Phenylmethyl)-: A Comprehensive Overview

The compound with CAS No. 13484-66-7, commonly referred to as 5'-Adenylic Acid, N-(Phenylmethyl)-, is a significant molecule in the field of biochemistry and molecular biology. This compound has garnered attention due to its unique structural properties and its potential applications in various scientific and therapeutic contexts. In this article, we will delve into the details of this compound, including its structure, synthesis, biological activity, and recent research findings.

5'-Adenylic Acid, N-(Phenylmethyl)- is a nucleotide analog with a modified ribose sugar moiety. The molecule consists of a purine base (adenine), a ribose sugar, and a phosphate group at the 5' position. The distinguishing feature of this compound is the substitution of the hydroxyl group at the 3' position of the ribose sugar with a phenylmethyl group (N-(Phenylmethyl)-). This modification imparts unique chemical and biological properties to the molecule, making it a valuable tool in research and development.

The synthesis of 5'-Adenylic Acid, N-(Phenylmethyl)- involves several steps, including the preparation of the adenine derivative and subsequent coupling with the modified ribose sugar. Recent advancements in synthetic chemistry have enabled researchers to streamline the synthesis process, improving yield and purity. These improvements have facilitated large-scale production of the compound for both academic and industrial applications.

One of the most notable applications of 5'-Adenylic Acid, N-(Phenylmethyl)- is in the study of nucleic acid chemistry and enzymology. The phenylmethyl group substitution at the 3' position confers resistance to certain enzymatic cleavages, making it an ideal substrate for studying RNA polymerases and other nucleic acid-modifying enzymes. This property has been exploited in various biochemical assays and enzyme kinetics studies.

Recent research has also highlighted the potential of 5'-Adenylic Acid, N-(Phenylmethyl)- as a building block for constructing modified oligonucleotides. These modified oligonucleotides exhibit enhanced stability and specificity compared to their unmodified counterparts, making them valuable tools in diagnostics and therapeutics. For instance, they have been used in the development of antisense oligonucleotides for targeting specific RNA sequences associated with diseases such as cancer and viral infections.

In addition to its role in nucleic acid chemistry, 5'-Adenylic Acid, N-(Phenylmethyl)- has been investigated for its potential in drug delivery systems. The phenylmethyl group substitution enhances the molecule's lipophilicity, allowing it to cross cellular membranes more efficiently. This property has been leveraged in designing drug delivery vehicles that can deliver therapeutic agents directly to target cells.

Recent studies have also explored the use of 5'-Adenylic Acid, N-(Phenylmethyl)- in CRISPR-Cas9 systems. The modified nucleotide has been shown to improve the efficiency and specificity of CRISPR-Cas9-mediated gene editing by stabilizing guide RNA structures and reducing off-target effects. This application underscores the versatility of this compound in modern biotechnology.

The biological activity of 5'-Adenylic Acid, N-(Phenylmethyl)- is further influenced by its ability to form stable complexes with proteins involved in nucleic acid metabolism. For example, studies have demonstrated that this compound can inhibit certain RNA helicases by mimicking natural substrates. Such findings have implications for understanding fundamental biological processes and developing novel therapeutic strategies.

In conclusion, 5'-Adenylic Acid, N-(Phenylmethyl)- (CAS No. 13484-66-7) is a versatile compound with diverse applications in biochemistry, molecular biology, and drug development. Its unique structural features and functional properties make it an invaluable tool for researchers across various disciplines. As ongoing research continues to uncover new insights into its potential uses, this compound is poised to play an increasingly important role in advancing scientific knowledge and therapeutic innovation.

13484-66-7 (IST5-002) Related Products

Recommended suppliers
NewCan Biotech Limited
(CAS:13484-66-7)N6-Benzyladenosine 5'-monophosphate sodium salt
NC9330
Purity:97%
Quantity:10g
Price ($):Inquiry
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