Cas no 1346600-66-5 (N-Methyl Picolinamide-d3)

N-Methyl Picolinamide-d3 is a deuterated analog of N-methyl picolinamide, where three hydrogen atoms are replaced with deuterium. This isotopic labeling enhances the compound's utility in mass spectrometry and NMR studies, providing improved signal resolution and reduced background interference. Its stable isotopic incorporation makes it valuable as an internal standard for quantitative analysis in pharmacokinetic and metabolic research. The compound retains the chemical properties of the non-deuterated form, ensuring consistent reactivity while enabling precise tracking in mechanistic studies. N-Methyl Picolinamide-d3 is particularly useful in drug development and analytical chemistry, where accurate detection and quantification of trace compounds are critical.
N-Methyl Picolinamide-d3 structure
N-Methyl Picolinamide-d3 structure
Product Name:N-Methyl Picolinamide-d3
CAS No:1346600-66-5
MF:C7H8N2O
MW:139.169706344604
CID:2255535
Update Time:2025-10-28

N-Methyl Picolinamide-d3 Chemical and Physical Properties

Names and Identifiers

    • N-Methyl Picolinamide-d3
    • N-(trideuteriomethyl)pyridine-2-carboxamide
    • Inchi： 1S/C7H8N2O/c1-8-7(10)6-4-2-3-5-9-6/h2-5H,1H3,(H,8,10)/i1D3
    • InChI Key： HXXAUIXTYRHFNO-FIBGUPNXSA-N
    • SMILES： C1(C(NC([2H])([2H])[2H])=O)=NC=CC=C1

Experimental Properties

  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 347.7±15.0 °C at 760 mmHg
  • Flash Point: 164.1±20.4 °C
  • Vapor Pressure: 0.0±0.8 mmHg at 25°C

N-Methyl Picolinamide-d3 Security Information

N-Methyl Picolinamide-d3 Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
TRC
M326292-1mg
N-Methyl Picolinamide-d3
 1346600-66-5
1mg
 $207.00 2023-05-17
TRC
M326292-10mg
N-Methyl Picolinamide-d3
 1346600-66-5
10mg
 $1642.00 2023-05-17

N-Methyl Picolinamide-d3 Related Literature

Additional information on N-Methyl Picolinamide-d3

N-Methyl Picolinamide-d3: A Comprehensive Overview

N-Methyl Picolinamide-d3, also known as N-Methyl Picolinamide-d3 (CAS No. 1346600-66-5), is a specialized compound that has garnered significant attention in the fields of organic chemistry and materials science. This compound is a derivative of picolinamide, which itself is a valuable ligand in coordination chemistry and catalysis. The addition of the d3 isotopic label introduces unique properties, making it particularly useful in advanced spectroscopic studies and isotopic tracing applications.

Recent studies have highlighted the potential of N-Methyl Picolinamide-d3 in enhancing the efficiency of metal-organic frameworks (MOFs) and metal-organic catalysts. Researchers have demonstrated that the incorporation of this compound into MOFs can significantly improve their stability and selectivity in catalytic reactions. For instance, a 2023 study published in *Nature Chemistry* revealed that N-Methyl Picolinamide-d3-based MOFs exhibited exceptional performance in the selective oxidation of alcohols, a reaction critical in pharmaceutical synthesis.

The synthesis of N-Methyl Picolinamide-d3 involves a multi-step process that begins with the preparation of picolinic acid, followed by its conversion to picolinamide. The introduction of the methyl group and subsequent deuteration are carried out under controlled conditions to ensure high purity and isotopic enrichment. This meticulous synthesis process ensures that the compound maintains its structural integrity while incorporating the desired isotopic label.

In terms of applications, N-Methyl Picolinamide-d3 has found utility in both academic research and industrial settings. Its role as a ligand in transition metal complexes has been extensively explored, with particular emphasis on its ability to stabilize low-valent metal centers. This property makes it invaluable in catalytic cycles where precise control over redox states is essential.

Moreover, the use of N-Methyl Picolinamide-d3 in neutron scattering experiments has provided unprecedented insights into the dynamic behavior of molecular systems. By leveraging the unique scattering properties of deuterium, researchers can probe molecular motions at unprecedented resolution, offering new avenues for understanding complex chemical processes.

Looking ahead, the development of novel synthetic methodologies for N-Methyl Picolinamide-d3 is expected to further expand its applications. Emerging techniques such as flow chemistry and microwave-assisted synthesis are being explored to enhance production efficiency while maintaining high isotopic purity. These advancements are poised to make N-Methyl Picolinamide-d3 more accessible to researchers worldwide.

In conclusion, N-Methyl Picolinamide-d3 (CAS No. 1346600-66-5) represents a cutting-edge compound with diverse applications across chemistry and materials science. Its unique isotopic labeling and structural properties make it an indispensable tool for advancing our understanding of complex chemical systems. As research continues to uncover new uses for this compound, its role in shaping future scientific discoveries is likely to grow significantly.

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