Cas no 1346569-65-0 (ETHYL 5-AMINO-6-IODOPYRIDINE-2-CARBOXYLATE)

ETHYL 5-AMINO-6-IODOPYRIDINE-2-CARBOXYLATE is a versatile heterocyclic compound featuring an amino and iodo functional group on a pyridine core, with an ethyl ester at the 2-position. This structure makes it a valuable intermediate in pharmaceutical and agrochemical synthesis, particularly for constructing complex molecules via cross-coupling reactions or further functionalization. The iodine substituent offers reactivity for palladium-catalyzed transformations, while the amino group enables derivatization or coordination chemistry. Its ethyl ester provides stability while remaining amenable to hydrolysis or transesterification. The compound is typically handled under inert conditions due to its sensitivity. It is used in research-scale applications requiring precise functional group manipulation.
ETHYL 5-AMINO-6-IODOPYRIDINE-2-CARBOXYLATE structure
1346569-65-0 structure
Product Name:ETHYL 5-AMINO-6-IODOPYRIDINE-2-CARBOXYLATE
CAS No:1346569-65-0
MF:C8H9IN2O2
MW:292.073734045029
CID:5159312
PubChem ID:119084937
Update Time:2025-11-02

ETHYL 5-AMINO-6-IODOPYRIDINE-2-CARBOXYLATE Chemical and Physical Properties

Names and Identifiers

    • ETHYL 5-AMINO-6-IODOPYRIDINE-2-CARBOXYLATE
    • ETHYL 5-AMINO-6-I0DOPYRI DINE-2-CARBOXYLATE
    • 1346569-65-0
    • WS-02628
    • MFCD28672326
    • D85820
    • Inchi: 1S/C8H9IN2O2/c1-2-13-8(12)6-4-3-5(10)7(9)11-6/h3-4H,2,10H2,1H3
    • InChI Key: VHNKLFOTQLAAEU-UHFFFAOYSA-N
    • SMILES: C1(C(OCC)=O)=NC(I)=C(N)C=C1

Computed Properties

  • Exact Mass: 291.97088g/mol
  • Monoisotopic Mass: 291.97088g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 4
  • Heavy Atom Count: 13
  • Rotatable Bond Count: 3
  • Complexity: 189
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 1.4
  • Topological Polar Surface Area: 65.2?2

ETHYL 5-AMINO-6-IODOPYRIDINE-2-CARBOXYLATE Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
eNovation Chemicals LLC
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A2B Chem LLC
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A2B Chem LLC
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Additional information on ETHYL 5-AMINO-6-IODOPYRIDINE-2-CARBOXYLATE

Comprehensive Guide to ETHYL 5-AMINO-6-IODOPYRIDINE-2-CARBOXYLATE (CAS No. 1346569-65-0)

ETHYL 5-AMINO-6-IODOPYRIDINE-2-CARBOXYLATE (CAS No. 1346569-65-0) is a specialized organic compound widely used in pharmaceutical research and fine chemical synthesis. This compound belongs to the pyridine derivative family, featuring an ethyl carboxylate group, an amino substituent, and an iodo functional group, making it a versatile intermediate for drug discovery and material science applications.

The molecular structure of ETHYL 5-AMINO-6-IODOPYRIDINE-2-CARBOXYLATE includes a pyridine ring substituted at the 2-position with an ethyl carboxylate group, which enhances its solubility in organic solvents. The presence of the iodo group at the 6-position and the amino group at the 5-position makes this compound highly reactive in cross-coupling reactions, such as Suzuki-Miyaura and Buchwald-Hartwig couplings, which are pivotal in modern medicinal chemistry.

Researchers frequently search for "ETHYL 5-AMINO-6-IODOPYRIDINE-2-CARBOXYLATE synthesis" or "CAS 1346569-65-0 applications" due to its growing importance in the development of novel therapeutics. This compound is particularly valuable in the synthesis of kinase inhibitors, which are a hot topic in cancer research. Kinase inhibitors target specific enzymes involved in cell signaling pathways, and pyridine-based intermediates like this one are often key building blocks in their design.

Another trending application of ETHYL 5-AMINO-6-IODOPYRIDINE-2-CARBOXYLATE is in the field of agrochemicals. With increasing global demand for sustainable farming solutions, researchers are exploring novel compounds that can act as eco-friendly pesticides or growth regulators. The iodo and amino functional groups in this molecule allow for further derivatization, enabling the creation of compounds with tailored biological activities.

From a commercial perspective, the market for pyridine derivatives is expanding rapidly, driven by their widespread use in pharmaceuticals, agrochemicals, and specialty chemicals. Suppliers and manufacturers often highlight "high-purity ETHYL 5-AMINO-6-IODOPYRIDINE-2-CARBOXYLATE" as a premium product for research and industrial applications. The compound's stability under standard storage conditions (room temperature, dry environment) makes it a practical choice for laboratories and production facilities.

In analytical chemistry, ETHYL 5-AMINO-6-IODOPYRIDINE-2-CARBOXYLATE can be characterized using techniques such as HPLC, NMR spectroscopy, and mass spectrometry. These methods ensure the compound's purity and confirm its structural integrity, which is critical for reproducible research outcomes. Scientists often search for "CAS 1346569-65-0 analytical data" to compare their results with established standards.

The safety profile of ETHYL 5-AMINO-6-IODOPYRIDINE-2-CARBOXYLATE is another area of interest. While it is not classified as a hazardous material, standard laboratory precautions should be followed, including the use of personal protective equipment (PPE) and proper ventilation. Researchers frequently inquire about "ETHYL 5-AMINO-6-IODOPYRIDINE-2-CARBOXYLATE safety data" to ensure compliance with workplace regulations.

Looking ahead, the demand for ETHYL 5-AMINO-6-IODOPYRIDINE-2-CARBOXYLATE is expected to grow, particularly in the pharmaceutical sector. With the rise of personalized medicine and targeted therapies, the need for high-quality intermediates like this will continue to increase. Innovations in synthetic methodologies, such as flow chemistry and biocatalysis, may further enhance the accessibility and scalability of this compound.

In summary, ETHYL 5-AMINO-6-IODOPYRIDINE-2-CARBOXYLATE (CAS No. 1346569-65-0) is a valuable compound with diverse applications in drug discovery, agrochemicals, and materials science. Its unique structural features and reactivity make it a sought-after intermediate for researchers and manufacturers alike. As the scientific community continues to explore new frontiers in chemistry and biology, compounds like this will play a pivotal role in driving innovation.

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