• 1. Evidence that the availability of an allylic hydrogen governs the regioselectivity of the Wacker oxidation
  Matthew J. Gaunt,Jinquan Yu,Jonathan B. Spencer Chem. Commun., 2001, 1844-1845
• 2. Embedding cyclic nitrone in mesoporous silica particles for EPR spin trapping of superoxide and other radicals?
  Eric Besson,Stéphane Gastaldi,Emily Bloch,Selma Aslan,Hakim Karoui,Olivier Ouari,Micael Hardy Analyst, 2019,144, 4194-4203
• 3. Excess electrons in lithium–ethylamine solutions—density, electrical conductivity and EPR studies
  Phys. Chem. Chem. Phys., 1999,1, 3561-3565
• 4. EWOD-driven droplet microfluidic device integrated with optoelectronic tweezers as an automated platform for cellular isolation and analysis?
  Gaurav J. Shah,Eric P.-Y. Chiou,Ming C. Wu,Chang-Jin “CJ” Kim Lab Chip, 2009,9, 1732-1739
• 5. Emerging 2D hybrid nanomaterials: towards enhanced sensitive and selective conductometric gas sensors at room temperature
  Hanie Hashtroudi,Ian D. R. Mackinnon J. Mater. Chem. C, 2020,8, 13108-13126

• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Phenylpropanes
• Other Chemical Reagents Derivatization Reagents
• Solvents and Organic Chemicals Organic Compounds Acids/Esters

Comprehensive Guide to p-Propylphenylboronic Acid (CAS No. 134150-01-9): Properties, Applications, and Industry Insights

p-Propylphenylboronic Acid (CAS No. 134150-01-9) is a versatile boronic acid derivative widely used in organic synthesis, pharmaceuticals, and material science. With the molecular formula C₉H₁₃BO₂, this compound features a propyl group attached to a phenyl ring, which is further functionalized with a boronic acid moiety. Its unique structure makes it a valuable intermediate for Suzuki-Miyaura cross-coupling reactions, a topic frequently searched by chemists and researchers in the field of catalysis and drug discovery.

The growing demand for boronic acid compounds in bioconjugation and medicinal chemistry has placed p-Propylphenylboronic Acid in the spotlight. Recent trends in AI-driven drug design and green chemistry have further amplified interest in this compound, as researchers explore its potential in targeted drug delivery and sustainable synthesis. Users often search for questions like "How to purify p-Propylphenylboronic Acid?" or "What solvents work best for Suzuki couplings with this reagent?", reflecting practical concerns in laboratory applications.

From a physicochemical perspective, p-Propylphenylboronic Acid typically appears as a white to off-white crystalline powder with a melting point range of 120-125°C. Its solubility profile—soluble in polar aprotic solvents like dimethyl sulfoxide (DMSO) and tetrahydrofuran (THF) but less so in water—makes it particularly useful for organic transformations under anhydrous conditions. These properties are crucial for researchers optimizing reaction conditions, a common search intent among synthetic chemists.

In pharmaceutical research, p-Propylphenylboronic Acid serves as a key building block for protease inhibitors and enzyme modulators. The compound's ability to form reversible covalent bonds with biological targets aligns with current trends in covalent drug discovery, a hot topic in precision medicine. Industry professionals frequently investigate its structure-activity relationships when developing new therapeutic agents for metabolic disorders.

The material science applications of p-Propylphenylboronic Acid are equally noteworthy. As interest grows in smart materials and responsive polymers, this compound finds use in creating boron-containing nanomaterials with applications in sensors and electronic devices. Searches for "boronic acid MOFs" (metal-organic frameworks) and "self-healing materials" often intersect with discussions about this chemical's unique properties.

Quality control of p-Propylphenylboronic Acid remains a critical concern, with researchers frequently searching for HPLC methods and spectroscopic characterization techniques (e.g., 1H NMR, 13C NMR, and IR spectroscopy). The compound's stability under various storage conditions—another common search query—requires attention to moisture sensitivity, prompting recommendations for desiccated storage at 2-8°C.

From an industrial manufacturing standpoint, p-Propylphenylboronic Acid production involves Grignard reactions or lithiation-borylation sequences, processes often explored in process chemistry forums. Recent advancements in continuous flow chemistry have opened new possibilities for its scalable synthesis, addressing search queries about "green synthesis of boronic acids" and "waste reduction in fine chemical production".

Environmental and handling considerations for p-Propylphenylboronic Acid generate significant search traffic, particularly regarding laboratory safety protocols and waste disposal methods. While not classified as hazardous under standard regulations, proper personal protective equipment (PPE) including gloves and eye protection is recommended—a practical detail often sought by first-time users.

The global market for p-Propylphenylboronic Acid reflects broader trends in specialty chemicals, with increasing demand from Asia-Pacific research institutions and contract manufacturing organizations (CMOs). Price fluctuations and supply chain dynamics for this high-purity reagent remain active discussion points in chemical procurement circles.

Looking ahead, p-Propylphenylboronic Acid (CAS No. 134150-01-9) continues to attract research attention due to emerging applications in biomedical imaging and theragnostic systems. Its compatibility with click chemistry approaches positions it well for future developments in combinatorial chemistry and high-throughput screening platforms—areas generating substantial search interest among chemical biology professionals.

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