• 1. Fast synthesis of red Li3BaSrLn3(WO4)8:Eu3+ phosphors for white LEDs under near-UV excitation by a microwave-assisted solid state reaction method and photoluminescence studies
  Bo Wei,Zhenyu Liu,Chen Xie,Shu Yang,Wentao Tang,Aiwei Gu,Wing-Tak Wong,Ka-Leung Wong J. Mater. Chem. C, 2015,3, 12322-12327
• 2. Establishing new scaling relations on two-dimensional MXenes for CO2 electroreduction?
  Albertus D. Handoko,Khoong Hong Khoo,Teck Leong Tan,Hongmei Jin,Zhi Wei Seh J. Mater. Chem. A, 2018,6, 21885-21890
• 3. Fast-pulsing NMR techniques for the detection of weak interactions: successful natural abundance probe of hydrogen bonds in peptides?
  Amandine Altmayer-Henzien,Valérie Declerck,David J. Aitken,Ewen Lescop,Denis Merlet,Jonathan Farjon Org. Biomol. Chem., 2013,11, 7611-7615
• 4. Evolution of important glucosinolates in three common Brassica vegetables during their processing into vegetable powder and in vitro gastric digestion
  Nan Fu,Naphaporn Chiewchan,Xiao Dong Chen Food Funct., 2020,11, 211-220
• 5. Fate of single walled carbon nanotubes in wetland ecosystems?
  Joseph H. Bisesi,Tara Sabo-Attwood Environ. Sci.: Nano, 2014,1, 574-583

Professional Introduction to 4-Bromobenzyl Alcohol, n-Propyl Ether (CAS No. 133842-35-0)

4-Bromobenzyl alcohol, n-propyl ether, with the chemical formula C₁₀H₁₃BrO, is a significant compound in the field of organic synthesis and pharmaceutical research. This compound, identified by its CAS number CAS No. 133842-35-0, has garnered attention due to its versatile applications in the development of novel therapeutic agents and intermediates. The unique structural properties of this ether make it a valuable building block for chemists and biologists working on complex molecular architectures.

The synthesis of 4-bromobenzyl alcohol, n-propyl ether involves a series of well-defined chemical reactions that highlight its reactivity and functional group compatibility. The presence of both a bromine substituent and an alcohol moiety allows for further functionalization, making it a preferred choice in cross-coupling reactions such as Suzuki-Miyaura and Buchwald-Hartwig couplings. These reactions are pivotal in constructing biaryl structures, which are common motifs in many pharmacologically active compounds.

In recent years, there has been a surge in research focused on developing innovative strategies for drug discovery and development. The compound 4-bromobenzyl alcohol, n-propyl ether has been explored in several cutting-edge studies due to its potential role as an intermediate in the synthesis of small-molecule inhibitors. For instance, researchers have utilized this compound to develop novel kinase inhibitors, which are essential in targeting various forms of cancer and inflammatory diseases. The bromine atom in the molecule serves as a handle for palladium-catalyzed reactions, enabling the introduction of diverse functional groups with high precision.

One of the most compelling aspects of 4-bromobenzyl alcohol, n-propyl ether is its utility in medicinal chemistry. The n-propyl ether group contributes to the lipophilicity of the molecule, which is often a critical factor in drug bioavailability. This property makes it an attractive candidate for designing orally active drugs that can efficiently traverse biological membranes. Furthermore, the compound’s ability to undergo selective modifications allows chemists to fine-tune its pharmacokinetic and pharmacodynamic profiles, thereby enhancing its therapeutic potential.

The pharmaceutical industry has shown particular interest in derivatives of 4-bromobenzyl alcohol, n-propyl ether due to their potential applications in treating neurological disorders. Recent studies have demonstrated that certain analogs of this compound exhibit neuroprotective effects by modulating key signaling pathways involved in neurodegeneration. For example, researchers have synthesized and characterized several derivatives that show promise in preclinical models of Alzheimer’s disease and Parkinson’s disease. These findings underscore the importance of exploring structurally diverse compounds like CAS No. 133842-35-0 for developing next-generation therapeutics.

In addition to its pharmaceutical applications, 4-bromobenzyl alcohol, n-propyl ether has found utility in materials science and agrochemical research. Its unique chemical properties make it a suitable candidate for synthesizing advanced materials with tailored functionalities. For instance, researchers have used this compound to develop novel polymers that exhibit enhanced mechanical strength and thermal stability. Similarly, in agrochemistry, derivatives of this compound have been investigated for their potential as bioactive agents that can protect crops from pests and diseases without adverse environmental impacts.

The future prospects of 4-bromobenzyl alcohol, n-propyl ether are vast and multifaceted. As synthetic methodologies continue to evolve, new ways to exploit its reactivity will emerge, opening up avenues for further innovation. Collaborative efforts between academia and industry are essential to fully harness the potential of this compound and translate laboratory discoveries into tangible benefits for society.

In conclusion, CAS No. 133842-35-0, also known as 4-bromobenzyl alcohol, n-propyl ether, is a versatile compound with significant implications across multiple scientific disciplines. Its role in pharmaceutical research alone underscores its importance as a molecular scaffold for developing novel drugs targeting various diseases. As research progresses, it is likely that new applications and derivatives will continue to emerge, further solidifying its place as a cornerstone in modern chemistry.

• 400837-92-5(2-((4-Bromobenzyl)oxy)ethanol)
• 133842-36-1(1-Bromo-4-butoxymethyl-benzene)
• 95068-22-7(1-Bromo-4-(ethoxymethyl)benzene)
• 1515-88-4(1-Bromo-4-(methoxymethyl)benzene)
• 3395-75-3(1-((Benzyloxy)methyl)-3-bromobenzene)
• 81395-27-9(1-(Benzyloxy)methyl-4-bromobenzene)
• 98446-84-5(1-Bromo-4-(propan-2-yloxy)methylbenzene)
• 1006865-32-2(Benzene,1-bromo-4-(2S)-3-methoxy-2-methylpropoxymethyl-)
• 170991-34-1(Benzene, 1-bromo-4-[2-(phenylmethoxy)ethyl]-)
• 95068-01-2(1-Bromo-3-(ethoxymethyl)benzene)