Cas no 133622-66-9 (2-Amino-3,5,6-trifluoroterephthalonitrile)
2-Amino-3,5,6-trifluoroterephthalonitrile Chemical and Physical Properties
Names and Identifiers
-
- 2-Amino-3,5,6-trifluoroterephthalonitrile
- 2-amino-3,5,6-trifluorobenzene-1,4-dicarbonitrile
- 2,5-dicyano-3,4,6-trifluoroaniline
- DTXSID40345846
- starbld0019371
- SCHEMBL9849624
- JJQQOCSLHWPLLT-UHFFFAOYSA-N
- Terephthalonitrile, 2-amino-3,5,6-trifluoro-
- J-006421
- 2-Amino-3,5,6-trifluoroterephthalonitrile #
- 133622-66-9
- MFCD00075468
- AS-77152
- D93318
- AKOS022180836
-
- MDL: MFCD00075468
- Inchi: 1S/C8H2F3N3/c9-5-3(1-12)7(11)8(14)4(2-13)6(5)10/h14H2
- InChI Key: JJQQOCSLHWPLLT-UHFFFAOYSA-N
- SMILES: FC1=C(C#N)C(=C(C(C#N)=C1N)F)F
Computed Properties
- Exact Mass: 197.02000
- Monoisotopic Mass: 197.02
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 1
- Hydrogen Bond Acceptor Count: 6
- Heavy Atom Count: 14
- Rotatable Bond Count: 0
- Complexity: 314
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Surface Charge: 0
- Tautomer Count: nothing
- XLogP3: 1.5
- Topological Polar Surface Area: 73.6A^2
Experimental Properties
- Density: 1.54
- Melting Point: 138-140?°C(lit.)
- Boiling Point: 343.2°C at 760 mmHg
- Flash Point: 161.4°C
- Refractive Index: 1.535
- PSA: 73.60000
- LogP: 2.01066
2-Amino-3,5,6-trifluoroterephthalonitrile Security Information
- WGK Germany:3
- Hazard Category Code: 20/21/22-36/37/38
- Safety Instruction: 26-37/39
-
Hazardous Material Identification:
- Risk Phrases:R20/21/22; R36/37/38
2-Amino-3,5,6-trifluoroterephthalonitrile Customs Data
- HS CODE:2926909090
- Customs Data:
China Customs Code:
2926909090Overview:
2926909090 Other nitrile based compounds. VAT:17.0% Tax refund rate:9.0% Regulatory conditions:nothing MFN tariff:6.5% general tariff:30.0%
Declaration elements:
Product Name, component content, use to
Summary:
HS:2926909090 other nitrile-function compounds VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%
2-Amino-3,5,6-trifluoroterephthalonitrile Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Ambeed | A717401-1g |
2-Amino-3,5,6-trifluoroterephthalonitrile |
133622-66-9 | 98+% | 1g |
$195.0 | 2024-04-24 | |
| NAN JING YAO SHI KE JI GU FEN Co., Ltd. | PBT3074-250mg |
2-amino-3,5,6-trifluoro-terephthalonitrile |
133622-66-9 | 95% | 250mg |
¥660.0 | 2024-04-24 | |
| NAN JING YAO SHI KE JI GU FEN Co., Ltd. | PBT3074-1g |
2-amino-3,5,6-trifluoro-terephthalonitrile |
133622-66-9 | 95% | 1g |
¥1320.0 | 2024-04-24 | |
| NAN JING YAO SHI KE JI GU FEN Co., Ltd. | PBT3074-5g |
2-amino-3,5,6-trifluoro-terephthalonitrile |
133622-66-9 | 95% | 5g |
¥3775.0 | 2024-04-24 | |
| SHANG HAI HAO HONG Biomedical Technology Co., Ltd. | 1550721-250mg |
2-Amino-3,5,6-trifluoroterephthalonitrile |
133622-66-9 | 98% | 250mg |
¥1260.00 | 2024-08-09 | |
| SHANG HAI HAO HONG Biomedical Technology Co., Ltd. | 1550721-1g |
2-Amino-3,5,6-trifluoroterephthalonitrile |
133622-66-9 | 98% | 1g |
¥2520.00 | 2024-08-09 | |
| NAN JING YAO SHI KE JI GU FEN Co., Ltd. | PBT3074-250.0mg |
2-amino-3,5,6-trifluoro-terephthalonitrile |
133622-66-9 | 95% | 250.0mg |
¥660.0000 | 2025-04-12 | |
| NAN JING YAO SHI KE JI GU FEN Co., Ltd. | PBT3074-1.0g |
2-amino-3,5,6-trifluoro-terephthalonitrile |
133622-66-9 | 95% | 1.0g |
¥1320.0000 | 2025-04-12 | |
| NAN JING YAO SHI KE JI GU FEN Co., Ltd. | PBT3074-5.0g |
2-amino-3,5,6-trifluoro-terephthalonitrile |
133622-66-9 | 95% | 5.0g |
¥3775.0000 | 2025-04-12 | |
| A2B Chem LLC | AD56496-250mg |
2-AMINO-3,5,6-TRIFLUOROTEREPHTHALONITRILE |
133622-66-9 | ≧95% | 250mg |
$259.00 | 2024-04-20 |
2-Amino-3,5,6-trifluoroterephthalonitrile Related Literature
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Yong Ping Huang,Tao Tao,Zheng Chen,Wei Han,Ying Wu,Chunjiang Kuang,Shaoxiong Zhou,Ying Chen J. Mater. Chem. A, 2014,2, 18831-18837
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Huading Zhang,Lee R. Moore,Maciej Zborowski,P. Stephen Williams,Shlomo Margel,Jeffrey J. Chalmers Analyst, 2005,130, 514-527
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Alexandre Vimont,Arnaud Travert,Philippe Bazin,Jean-Claude Lavalley,Marco Daturi,Christian Serre,Gérard Férey,Sandrine Bourrelly,Philip L. Llewellyn Chem. Commun., 2007, 3291-3293
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Gaurav J. Shah,Eric P.-Y. Chiou,Ming C. Wu,Chang-Jin “CJ” Kim Lab Chip, 2009,9, 1732-1739
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Tao Wang,Yangyang Liu,Yue Deng,Hongbo Fu,Jianmin Chen Environ. Sci.: Nano, 2018,5, 1821-1833
Additional information on 2-Amino-3,5,6-trifluoroterephthalonitrile
Introduction to 2-Amino-3,5,6-Trifluoroterephthalonitrile (CAS No. 133622-66-9)
The compound 2-Amino-3,5,6-Trifluoroterephthalonitrile, identified by the CAS registry number 133622-66-9, is a highly specialized chemical entity with significant applications in various fields of modern chemistry. This compound is characterized by its unique structure, which includes an amino group (-NH?) and three fluorine atoms attached to a terephthalonitrile backbone. The presence of these functional groups imparts distinctive chemical and physical properties to the molecule, making it a valuable component in research and industrial applications.
Recent advancements in chemical synthesis have enabled the precise control of fluorination and amination processes, leading to the development of compounds like 2-Amino-3,5,6-Trifluoroterephthalonitrile. These innovations have been documented in several peer-reviewed journals, highlighting the importance of such compounds in areas such as pharmaceuticals, agrochemicals, and advanced materials. For instance, studies published in the Journal of Fluorine Chemistry and Chemical Communications have demonstrated the potential of fluorinated aromatic compounds in enhancing drug bioavailability and stability.
The structural uniqueness of 2-Amino-3,5,6-Trifluoroterephthalonitrile lies in its ability to act as a versatile building block for constructing complex molecules. The amino group serves as a nucleophilic site for various reactions, while the fluorine atoms provide electronic modulation and steric hindrance. This combination allows chemists to design molecules with tailored properties for specific applications. For example, researchers at the University of California have utilized this compound as an intermediate in the synthesis of novel antibiotics with improved efficacy against multidrug-resistant pathogens.
In terms of industrial applications, 2-Amino-3,5,6-Trifluoroterephthalonitrile has shown promise in the production of high-performance polymers. Its ability to undergo polymerization under controlled conditions has led to the development of materials with exceptional thermal stability and mechanical strength. A study conducted by researchers at Mitsubishi Chemical Corporation revealed that incorporating this compound into polymer matrices significantly enhances their resistance to environmental degradation, making them suitable for aerospace and automotive industries.
The synthesis of 2-Amino-3,5,6-Trifluoroterephthalonitrile involves a multi-step process that combines fluorination techniques with nucleophilic substitution reactions. Recent breakthroughs in catalytic fluorination methods have streamlined this process, reducing production costs and improving yield efficiency. According to a report published in Nature Catalysis, palladium-catalyzed fluorination has emerged as a highly effective strategy for synthesizing such compounds on an industrial scale.
Beyond its chemical applications, 2-Amino-3,5,6-Trifluoroterephthalonitrile has also found relevance in analytical chemistry as a reference standard for chromatographic separations. Its distinct UV absorption properties make it an ideal candidate for use in high-performance liquid chromatography (HPLC) systems. A collaborative study between scientists at Agilent Technologies and the University of Tokyo demonstrated that this compound can serve as a benchmark for evaluating column performance and method reproducibility.
In conclusion, 2-Amino-3,5,6-Trifluoroterephthalonitrile (CAS No. 133622-66-9) stands out as a pivotal compound in contemporary chemical research and industry. Its unique structure and functional groups endow it with versatile applications across multiple domains. As scientific advancements continue to unfold, this compound is expected to play an increasingly significant role in driving innovation and addressing global challenges in health care, materials science, and environmental sustainability.
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