Cas no 1334413-33-0 (Tert-butyl 4-fluoro-3-oxopiperidine-1-carboxylate)
Tert-butyl 4-fluoro-3-oxopiperidine-1-carboxylate is a fluorinated piperidine derivative commonly used as an intermediate in organic synthesis and pharmaceutical research. The tert-butyloxycarbonyl (Boc) protecting group enhances stability and facilitates selective deprotection under mild acidic conditions. The 4-fluoro substitution and 3-oxo functionality make it a versatile building block for constructing complex molecules, particularly in medicinal chemistry for the development of bioactive compounds. Its well-defined reactivity profile allows for efficient further functionalization, including nucleophilic additions or reductions. The compound is typically handled under inert conditions due to its sensitivity to moisture and strong bases. Suitable for applications requiring controlled fluorination and carbonyl chemistry.
1334413-33-0 structure
Product Name:Tert-butyl 4-fluoro-3-oxopiperidine-1-carboxylate
CAS No:1334413-33-0
MF:C10H16FNO3
MW:217.23734664917
MDL:MFCD20261388
CID:1091563
PubChem ID:72698286
Update Time:2025-06-07
Tert-butyl 4-fluoro-3-oxopiperidine-1-carboxylate Chemical and Physical Properties
Names and Identifiers
-
- tert-Butyl 4-fluoro-3-oxopiperidine-1-carboxylate
- 1-Boc-4-fluoro-3-oxopiperidine
- FCH1629549
- AM807492
- PC430154
- AX8283496
- t-Butyl 4-fluoro-3-oxopiperidine-1-carboxylate
- 1-Piperidinecarboxylic acid,4-fluoro-3-oxo-,1,1-dimethylethyl
- 4-Fluoro-3-oxo-piperidine-1-carboxylic acid tert-butyl ester
- s11807
- AS-68046
- tert-butyl4-fluoro-3-oxopiperidine-1-carboxylate
- MFCD20261388
- SCHEMBL23274802
- AKOS022178237
- CS-W001408
- SB43980
- 1334413-33-0
- Tert-butyl 4-fluoro-3-oxopiperidine-1-carboxylate
-
- MDL： MFCD20261388
- Inchi： 1S/C10H16FNO3/c1-10(2,3)15-9(14)12-5-4-7(11)8(13)6-12/h7H,4-6H2,1-3H3
- InChI Key： ZRQXQCQSKSYTBU-UHFFFAOYSA-N
- SMILES： FC1C(CN(C(=O)OC(C)(C)C)CC1)=O
Computed Properties
- Exact Mass: 217.11142153g/mol
- Monoisotopic Mass: 217.11142153g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 0
- Hydrogen Bond Acceptor Count: 4
- Heavy Atom Count: 15
- Rotatable Bond Count: 2
- Complexity: 272
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 1
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Topological Polar Surface Area: 46.6
- XLogP3: 1.5
Experimental Properties
- Density: 1.2±0.1 g/cm3
- Boiling Point: 288.7±40.0 °C at 760 mmHg
- Flash Point: 128.4±27.3 °C
- Vapor Pressure: 0.0±0.6 mmHg at 25°C
Tert-butyl 4-fluoro-3-oxopiperidine-1-carboxylate Security Information
- Signal Word：warning
- Hazard Statement： H303May be harmful if swallowed+H313Skin contact may be harmful+H333Inhalation may be harmful to the body
- Warning Statement： P264+P280+P305+P351+P338+P337+P313
- Safety Instruction： H303+H313+H333
- Storage Condition：storage at -4℃ (1-2weeks), longer storage period at -20℃ (1-2years)
Tert-butyl 4-fluoro-3-oxopiperidine-1-carboxylate Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Alichem | A129007735-1g |
tert-Butyl 4-fluoro-3-oxopiperidine-1-carboxylate |
1334413-33-0 | 95% | 1g |
918.75 USD | 2021-06-01 | |
| TRC | B702840-10mg |
Tert-Butyl 4-Fluoro-3-Oxopiperidine-1-Carboxylate |
1334413-33-0 | 10mg |
$ 70.00 | 2022-06-06 | ||
| TRC | B702840-50mg |
Tert-Butyl 4-Fluoro-3-Oxopiperidine-1-Carboxylate |
1334413-33-0 | 50mg |
$ 230.00 | 2022-06-06 | ||
| TRC | B702840-100mg |
Tert-Butyl 4-Fluoro-3-Oxopiperidine-1-Carboxylate |
1334413-33-0 | 100mg |
$ 340.00 | 2022-06-06 | ||
| SHANG HAI MAI KE LIN SHENG HUA Technology Co., Ltd. | T905639-25mg |
tert-butyl4-fluoro-3-oxopiperidine-1-carboxylate |
1334413-33-0 | ≥95% | 25mg |
1,710.00 | 2021-05-17 | |
| Chemenu | CM179880-1g |
tert-Butyl 4-fluoro-3-oxopiperidine-1-carboxylate |
1334413-33-0 | 95% | 1g |
$1018 | 2021-08-05 | |
| Chemenu | CM179880-250mg |
tert-Butyl 4-fluoro-3-oxopiperidine-1-carboxylate |
1334413-33-0 | 95%+ | 250mg |
$672 | 2024-08-02 | |
| Chemenu | CM179880-1g |
tert-Butyl 4-fluoro-3-oxopiperidine-1-carboxylate |
1334413-33-0 | 95%+ | 1g |
$1344 | 2024-08-02 | |
| eNovation Chemicals LLC | D772026-100mg |
tert-Butyl 4-fluoro-3-oxopiperidine-1-carboxylate |
1334413-33-0 | 95% | 100mg |
$255 | 2025-02-19 | |
| eNovation Chemicals LLC | D772026-250mg |
tert-Butyl 4-fluoro-3-oxopiperidine-1-carboxylate |
1334413-33-0 | 95% | 250mg |
$460 | 2025-02-19 |
Tert-butyl 4-fluoro-3-oxopiperidine-1-carboxylate Related Literature
-
Jadwiga Frelek,Marcin Górecki,Marta ?aszcz,Agata Suszczyńska,Elemér Vass,Wojciech J. Szczepek Chem. Commun., 2012,48, 5295-5297
-
Tengfei Yu,Yuehan Wu,Wei Li,Bin Li RSC Adv., 2014,4, 34134-34143
-
Eric Besson,Stéphane Gastaldi,Emily Bloch,Selma Aslan,Hakim Karoui,Olivier Ouari,Micael Hardy Analyst, 2019,144, 4194-4203
-
Ross Harder,David C. Dunand,Ian McNulty Nanoscale, 2017,9, 5686-5693
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5. Excimer emission and magnetoluminescence of radical-based zinc(ii) complexes doped in host crystals?Shojiro Kimura,Tetsuro Kusamoto Chem. Commun., 2020,56, 11195-11198
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