Cas no 13332-25-7 (Benzene, 1-bromo-2,3,5-trifluoro-4-methoxy-)
Benzene, 1-bromo-2,3,5-trifluoro-4-methoxy- Chemical and Physical Properties
Names and Identifiers
-
- Benzene, 1-bromo-2,3,5-trifluoro-4-methoxy-
- 13332-25-7
- 1-bromo-2,3,5-trifluoro-4-methoxybenzene
- DTXSID601277337
- 4-Bromo-2,3,6-trifluoroanisole
- SCHEMBL5208683
-
- Inchi: 1S/C7H4BrF3O/c1-12-7-4(9)2-3(8)5(10)6(7)11/h2H,1H3
- InChI Key: BDWNSULXTJREEF-UHFFFAOYSA-N
- SMILES: BrC1C=C(C(=C(C=1F)F)OC)F
Computed Properties
- Exact Mass: 239.94
- Monoisotopic Mass: 239.94
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 0
- Hydrogen Bond Acceptor Count: 4
- Heavy Atom Count: 12
- Rotatable Bond Count: 1
- Complexity: 158
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Topological Polar Surface Area: 9.2A^2
- XLogP3: 2.9
Benzene, 1-bromo-2,3,5-trifluoro-4-methoxy- Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Alichem | A013020572-250mg |
4-Bromo-2,3,6-trifluoroanisole |
13332-25-7 | 97% | 250mg |
499.20 USD | 2021-06-24 | |
| Alichem | A013020572-500mg |
4-Bromo-2,3,6-trifluoroanisole |
13332-25-7 | 97% | 500mg |
839.45 USD | 2021-06-24 | |
| Alichem | A013020572-1g |
4-Bromo-2,3,6-trifluoroanisole |
13332-25-7 | 97% | 1g |
1,490.00 USD | 2021-06-24 |
Benzene, 1-bromo-2,3,5-trifluoro-4-methoxy- Related Literature
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Peiyuan Zeng,Xiaoxiao Wang,Ming Ye,Qiuyang Ma,Jianwen Li,Wanwan Wang,Baoyou Geng,Zhen Fang RSC Adv., 2016,6, 23074-23084
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Norihito Fukui,Keisuke Fujimoto,Hideki Yorimitsu,Atsuhiro Osuka Dalton Trans., 2017,46, 13322-13341
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Kay S. McMillan,Anthony G. McCluskey,Annette Sorensen,Marie Boyd,Michele Zagnoni Analyst, 2016,141, 100-110
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Vishwesh Venkatraman,Marco Foscato,Vidar R. Jensen,Bj?rn K?re Alsberg J. Mater. Chem. A, 2015,3, 9851-9860
Additional information on Benzene, 1-bromo-2,3,5-trifluoro-4-methoxy-
Benzene, 1-bromo-2,3,5-trifluoro-4-methoxy-
Benzene derivatives have long been of significant interest in the fields of organic chemistry, pharmaceuticals, and materials science due to their unique electronic properties and versatile applications. Among these derivatives, 1-bromo-2,3,5-trifluoro-4-methoxy-benzene, also known by its CAS Registry Number 13332-25-7, stands out as a highly functionalized aromatic compound with a complex substitution pattern. This compound features multiple electronegative substituents, including bromo, trifluoro, and methoxy groups, which endow it with distinct chemical reactivity and physical properties.
The presence of these substituents renders the molecule highly electron-deficient due to the strong electron-withdrawing effects of the trifluoro group and the bromo atom, while the methoxy group provides a mild electron-donating effect. This balance of electronic effects makes 1-bromo-2,3,5-trifluoro-4-methoxy-benzene an excellent candidate for various chemical reactions and applications.
Recent studies have highlighted the potential of this compound in pharmaceutical synthesis. Its highly substituted aromatic ring serves as a valuable scaffold for constructing complex molecules with diverse biological activities. For instance, researchers have explored its use as an intermediate in the synthesis of kinase inhibitors, which are critical for treating various cancers and inflammatory diseases.
Moreover, the compound's electronic properties make it suitable for applications in materials science. Its strong electron-deficiency enhances its ability to participate in charge-transfer interactions, making it a promising candidate for use in organic electronics, such as light-emitting diodes (LEDs) and field-effect transistors (FETs). Recent advancements in this area have demonstrated the potential of such aromatic compounds in creating more efficient and durable electronic devices.
Environmental considerations are another important aspect when working with 1-bromo-2,3,5-trifluoro-4-methoxy-benzene. The compound's stability and reactivity must be carefully managed to minimize its environmental impact. Research into green chemistry approaches for synthesizing and handling such compounds is ongoing, aiming to develop more sustainable practices.
Finally, the safety profile of this compound is a critical factor in its application. While it is not classified as a hazardous material under current regulations, proper handling and disposal protocols must be followed to ensure the well-being of laboratory personnel and the environment.
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