Cas no 13188-89-1 (H-D-Asp(OBzl)-OH)
H-D-Asp(OBzl)-OH Chemical and Physical Properties
Names and Identifiers
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- (R)-2-Amino-4-(benzyloxy)-4-oxobutanoic acid
- H-D-Asp(OBzl)-OH
- D-Aspartic acid beta-benzyl ester
- D-Aspartic acid ?-benzyl ester
- D-Aspartic acid β-benzyl ester
- 2-azanyl-4-oxidanylidene-4-phenylmethoxy-butanoic acid
- D-Asp(OBzl)-OH
- D-ASPARTIC ACID(OBZL)-OH
- D-ASPARTIC ACID-B-BENZYLESTER
- D-ASPARTIC ACID 4-BENZYL ESTER
- H-D-Asp(OBn)-OH
- (2R)-2-amino-4-oxo-4-phenylmethoxybutanoic acid
- FCH2720117
- (R)-2-Amino-succinicacid4-benzylester
- AX8018019
- X5805
- ST24030744
- 188A891
- J-300064
- AKOS016842889
- Q-101791
- A806327
- 2-amino-4-benzyloxy-4-oxo-butanoic acid
- MFCD00077100
- SCHEMBL5898461
- AS-12179
- CS-W006060
- VGALFAWDSNRXJK-SECBINFHSA-N
- 13188-89-1
- (2R)-2-azaniumyl-4-oxo-4-phenylmethoxybutanoate
- (2R)-2-AMINO-4-(BENZYLOXY)-4-OXOBUTANOIC ACID
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- MDL： MFCD00077100
- Inchi： 1S/C11H13NO4/c12-9(11(14)15)6-10(13)16-7-8-4-2-1-3-5-8/h1-5,9H,6-7,12H2,(H,14,15)/t9-/m1/s1
- InChI Key： VGALFAWDSNRXJK-SECBINFHSA-N
- SMILES： O(C(C[C@H](C(=O)O)N)=O)CC1C=CC=CC=1
Computed Properties
- Exact Mass: 263.07900
- Monoisotopic Mass: 223.08445790g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 2
- Hydrogen Bond Acceptor Count: 5
- Heavy Atom Count: 16
- Rotatable Bond Count: 6
- Complexity: 248
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 1
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Topological Polar Surface Area: 89.6
- XLogP3: -2
Experimental Properties
- Color/Form: No data avaiable
- Density: 1.4±0.1 g/cm3
- Melting Point: No data available
- Boiling Point: 525.4±50.0 °C at 760 mmHg
- Flash Point: 271.5±30.1 °C
- PSA: 83.91000
- LogP: 1.33670
- Vapor Pressure: No data available
H-D-Asp(OBzl)-OH Security Information
- Signal Word：warning
- Hazard Statement： H303+H313+H333
- Warning Statement： P264+P280+P305+P351+P338+P337+P313
- Safety Instruction： H303+H313+H333
- Storage Condition：Store at 4 ° C, -4 ° C is better
H-D-Asp(OBzl)-OH Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Chemenu | CM248832-25g |
H-D-Asp(OBzl)-OH |
13188-89-1 | 97% | 25g |
$197 | 2021-06-09 | |
| Chemenu | CM248832-100g |
H-D-Asp(OBzl)-OH |
13188-89-1 | 97% | 100g |
$421 | 2021-06-09 | |
| SHANG HAI MAI KE LIN SHENG HUA Technology Co., Ltd. | H843146-5g |
H-D-Asp(OBzl)-OH |
13188-89-1 | 97% | 5g |
172.00 | 2021-05-17 | |
| TRC | A780118-50mg |
H-D-ASP(OBZL)-OH |
13188-89-1 | 50mg |
$ 50.00 | 2022-06-07 | ||
| TRC | A780118-100mg |
H-D-ASP(OBZL)-OH |
13188-89-1 | 100mg |
$ 65.00 | 2022-06-07 | ||
| TRC | A780118-500mg |
H-D-ASP(OBZL)-OH |
13188-89-1 | 500mg |
$ 80.00 | 2022-06-07 | ||
| Fluorochem | 222152-1g |
H-D-Asp(OBzl)-OH |
13188-89-1 | 95% | 1g |
￡12.00 | 2022-03-01 | |
| Fluorochem | 222152-5g |
H-D-Asp(OBzl)-OH |
13188-89-1 | 95% | 5g |
￡39.00 | 2022-03-01 | |
| Fluorochem | 222152-10g |
H-D-Asp(OBzl)-OH |
13188-89-1 | 95% | 10g |
￡71.00 | 2022-03-01 | |
| Chemenu | CM248832-25g |
H-D-Asp(OBzl)-OH |
13188-89-1 | 97% | 25g |
$197 | 2024-08-02 |
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H-D-Asp(OBzl)-OH Related Literature
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Yukiya Kitayama Polym. Chem., 2014,5, 2784-2792
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Peiyuan Zeng,Xiaoxiao Wang,Ming Ye,Qiuyang Ma,Jianwen Li,Wanwan Wang,Baoyou Geng,Zhen Fang RSC Adv., 2016,6, 23074-23084
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Xiaoming Liu,Zachary D. Hood,Wangda Li,Donovan N. Leonard,Arumugam Manthiram,Miaofang Chi J. Mater. Chem. A, 2021,9, 2111-2119
Additional information on H-D-Asp(OBzl)-OH
Compound CAS No. 13188-89-1: H-D-Asp(OBzl)-OH
The compound with CAS number 13188-89-1, commonly referred to as H-D-Asp(OBzl)-OH, is a significant molecule in the field of organic chemistry and biochemistry. This compound is a derivative of aspartic acid, a naturally occurring amino acid, with a specific modification involving the introduction of a benzyl group (OBzl) at the alpha-carbon. The benzyl group serves as a protecting group, which is often used in peptide synthesis to prevent unwanted side reactions during the synthesis process.
H-D-Asp(OBzl)-OH has been extensively studied for its role in peptide synthesis and its potential applications in drug discovery. Recent research has highlighted its importance in the development of bioactive peptides, particularly in the context of enzymatic catalysis and peptide-based therapeutics. The compound's structure allows for precise control over the stereochemistry and reactivity of peptides, making it a valuable tool in medicinal chemistry.
One of the most notable advancements involving H-D-Asp(OBzl)-OH is its use in the synthesis of cyclic peptides. These cyclic structures are known for their stability and bioactivity, often mimicking the functions of natural peptides found in biological systems. By incorporating H-D-Asp(OBzl)-OH into peptide sequences, researchers have been able to create molecules with enhanced affinity for specific targets, such as receptors or enzymes. This has opened new avenues for the development of targeted therapies and biological mimics.
Moreover, the compound has been utilized in studies exploring the relationship between peptide structure and function. For instance, investigations into the secondary structure formation of peptides incorporating H-D-Asp(OBzl)-OH have provided insights into how modifications at the alpha-carbon influence folding patterns and overall stability. These findings are crucial for designing peptides with desired pharmacokinetic properties, such as improved solubility and reduced immunogenicity.
In addition to its role in peptide synthesis, H-D-Asp(OBzl)-OH has also been employed as a building block in the construction of more complex molecules. Its versatility lies in its ability to participate in various coupling reactions, including those mediated by carbodiimides or mixed carbonates. This makes it an essential component in modern solid-phase synthesis protocols, where precise control over each step is critical for obtaining high-quality products.
Recent studies have also explored the use of H-D-Asp(OBzl)-OH in conjunction with other protecting groups to create libraries of diverse peptides. These libraries are invaluable for high-throughput screening campaigns aimed at identifying novel bioactive compounds. By leveraging the unique properties of H-D-Asp(OBzl)-OH, researchers can efficiently generate large collections of peptides with varying functionalities, significantly accelerating the drug discovery process.
The importance of H-D-Asp(OBzl)-OH extends beyond laboratory research. Its application in industrial settings has contributed to the development of advanced biopharmaceuticals and diagnostic agents. For example, peptides synthesized using this compound have been used as components in vaccines, where their ability to induce strong immune responses is highly desirable.
In conclusion, CAS No. 13188-89-1 (H-D-Asp(OBzl)-OH) stands out as a pivotal molecule in contemporary organic chemistry and biochemistry. Its role in peptide synthesis, drug discovery, and structural studies underscores its significance in advancing our understanding of molecular biology and therapeutic development. As research continues to uncover new applications for this compound, its impact on science and medicine is expected to grow further.
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