Cas no 131860-40-7 ((E)-Methyl 2-(2-((6-(2-hydroxyphenoxy)pyrimidin-4-yl)oxy)phenyl)-3-methoxyacrylate)

(E)-Methyl 2-(2-((6-(2-hydroxyphenoxy)pyrimidin-4-yl)oxy)phenyl)-3-methoxyacrylate is a synthetic intermediate with potential applications in agrochemical and pharmaceutical research. Its structure features a pyrimidinyloxy-phenyl core linked to a methoxyacrylate moiety, offering versatility for further functionalization. The compound’s phenolic hydroxyl group enhances reactivity, facilitating derivatization or coordination chemistry. The conjugated (E)-alkene configuration contributes to stability, while the methoxy groups influence electronic properties, making it suitable for studies in ligand design or bioactive molecule development. Its precise synthesis and well-defined stereochemistry ensure reproducibility in research applications. This compound may serve as a precursor for fungicides or kinase inhibitors, though further studies are required to confirm specific biological activity.
(E)-Methyl 2-(2-((6-(2-hydroxyphenoxy)pyrimidin-4-yl)oxy)phenyl)-3-methoxyacrylate structure
131860-40-7 structure
Product Name:(E)-Methyl 2-(2-((6-(2-hydroxyphenoxy)pyrimidin-4-yl)oxy)phenyl)-3-methoxyacrylate
CAS No:131860-40-7
MF:C21H18N2O6
MW:394.377425670624
CID:1031005
PubChem ID:56605176
Update Time:2025-11-02

(E)-Methyl 2-(2-((6-(2-hydroxyphenoxy)pyrimidin-4-yl)oxy)phenyl)-3-methoxyacrylate Chemical and Physical Properties

Names and Identifiers

    • (E)-Methyl 2-(2-((6-(2-hydroxyphenoxy)pyrimidin-4-yl)oxy)phenyl)-3-methoxyacrylate
    • methyl (E)-2-[2-[6-(2-hydroxyphenoxy)pyrimidin-4-yl]oxyphenyl]-3-methoxyprop-2-enoate
    • DTXSID80717962
    • (E)-Methyl2-(2-((6-(2-hydroxyphenoxy)pyrimidin-4-yl)oxy)phenyl)-3-methoxyacrylate
    • SCHEMBL9125875
    • SCHEMBL9125856
    • Methyl (2E)-2-(2-{[6-(2-hydroxyphenoxy)pyrimidin-4-yl]oxy}phenyl)-3-methoxyprop-2-enoate
    • 131860-40-7
    • Inchi： 1S/C21H18N2O6/c1-26-12-15(21(25)27-2)14-7-3-5-9-17(14)28-19-11-20(23-13-22-19)29-18-10-6-4-8-16(18)24/h3-13,24H,1-2H3/b15-12+
    • InChI Key： YNADFEGFUROIDY-NTCAYCPXSA-N
    • SMILES： O(C1C=C(N=CN=1)OC1C=CC=CC=1O)C1C=CC=CC=1/C(=C\OC)/C(=O)OC

Computed Properties

  • Exact Mass: 394.11648630g/mol
  • Monoisotopic Mass: 394.11648630g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 8
  • Heavy Atom Count: 29
  • Rotatable Bond Count: 8
  • Complexity: 557
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 1
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 3.6
  • Topological Polar Surface Area: 100?2

(E)-Methyl 2-(2-((6-(2-hydroxyphenoxy)pyrimidin-4-yl)oxy)phenyl)-3-methoxyacrylate Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
Alichem
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(E)-Methyl 2-(2-((6-(2-hydroxyphenoxy)pyrimidin-4-yl)oxy)phenyl)-3-methoxyacrylate
 131860-40-7 95%
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 783.36 USD 2021-06-01
Chemenu
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Chemenu
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(E)-Methyl 2-(2-((6-(2-hydroxyphenoxy)pyrimidin-4-yl)oxy)phenyl)-3-methoxyacrylate Suppliers

Amadis Chemical Company Limited
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(CAS:131860-40-7)(E)-Methyl 2-(2-((6-(2-hydroxyphenoxy)pyrimidin-4-yl)oxy)phenyl)-3-methoxyacrylate
Order Number:A983466
Stock Status:in Stock
Quantity:1g
Purity:99%
Pricing Information Last Updated:Friday, 30 August 2024 17:39
Price ($):670.0

(E)-Methyl 2-(2-((6-(2-hydroxyphenoxy)pyrimidin-4-yl)oxy)phenyl)-3-methoxyacrylate Related Literature

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Additional information on (E)-Methyl 2-(2-((6-(2-hydroxyphenoxy)pyrimidin-4-yl)oxy)phenyl)-3-methoxyacrylate

Research Brief on (E)-Methyl 2-(2-((6-(2-hydroxyphenoxy)pyrimidin-4-yl)oxy)phenyl)-3-methoxyacrylate (CAS: 131860-40-7)

In recent years, the compound (E)-Methyl 2-(2-((6-(2-hydroxyphenoxy)pyrimidin-4-yl)oxy)phenyl)-3-methoxyacrylate (CAS: 131860-40-7) has garnered significant attention in the field of chemical biology and pharmaceutical research. This molecule, characterized by its unique structural features, has shown promising potential in various therapeutic applications, particularly in the development of novel antifungal agents. The presence of the hydroxyphenoxy and methoxyacrylate moieties in its structure contributes to its biological activity, making it a subject of intense study.

Recent studies have focused on elucidating the mechanism of action of this compound, particularly its interaction with fungal cell membranes. Research indicates that (E)-Methyl 2-(2-((6-(2-hydroxyphenoxy)pyrimidin-4-yl)oxy)phenyl)-3-methoxyacrylate exhibits strong inhibitory effects against a broad spectrum of fungal pathogens, including Candida albicans and Aspergillus fumigatus. The compound's ability to disrupt ergosterol biosynthesis, a critical component of fungal cell membranes, has been identified as a key factor in its antifungal activity. This mechanism is similar to that of other well-known antifungal agents, but with potentially fewer side effects and higher efficacy.

In addition to its antifungal properties, recent investigations have explored the compound's potential applications in other therapeutic areas. Preliminary data suggest that (E)-Methyl 2-(2-((6-(2-hydroxyphenoxy)pyrimidin-4-yl)oxy)phenyl)-3-methoxyacrylate may also exhibit anti-inflammatory and immunomodulatory effects. These findings open new avenues for its use in treating inflammatory diseases and autoimmune disorders. However, further in vivo studies are required to validate these observations and assess the compound's safety profile.

The synthesis and optimization of (E)-Methyl 2-(2-((6-(2-hydroxyphenoxy)pyrimidin-4-yl)oxy)phenyl)-3-methoxyacrylate have also been a focus of recent research. Advances in synthetic chemistry have enabled the production of this compound with higher yields and purity, facilitating its use in preclinical and clinical studies. Researchers have also explored structural modifications to enhance its pharmacokinetic properties, such as bioavailability and metabolic stability. These efforts are crucial for the development of a viable drug candidate based on this molecule.

Despite the promising findings, challenges remain in the development of (E)-Methyl 2-(2-((6-(2-hydroxyphenoxy)pyrimidin-4-yl)oxy)phenyl)-3-methoxyacrylate as a therapeutic agent. Issues such as potential toxicity, drug resistance, and formulation stability need to be addressed in future studies. Collaborative efforts between chemists, biologists, and pharmacologists will be essential to overcome these hurdles and translate the compound's potential into clinical applications.

In conclusion, (E)-Methyl 2-(2-((6-(2-hydroxyphenoxy)pyrimidin-4-yl)oxy)phenyl)-3-methoxyacrylate (CAS: 131860-40-7) represents a promising candidate for the development of novel antifungal and potentially anti-inflammatory agents. Continued research into its mechanism of action, synthetic optimization, and therapeutic applications will be critical for its advancement in the pharmaceutical pipeline. The compound's unique structural and biological properties make it a valuable subject of study in the field of chemical biology and drug discovery.

131860-40-7 ((E)-Methyl 2-(2-((6-(2-hydroxyphenoxy)pyrimidin-4-yl)oxy)phenyl)-3-methoxyacrylate) Related Products

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Amadis Chemical Company Limited
(CAS:131860-40-7)(E)-Methyl 2-(2-((6-(2-hydroxyphenoxy)pyrimidin-4-yl)oxy)phenyl)-3-methoxyacrylate
A983466
Purity:99%
Quantity:1g
Price ($):670.0
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