• 1. Fe3O4 nanoclusters highly dispersed on a porous graphene support as an additive for improving the hydrogen storage properties of LiBH4?
  Guang Xu,Wei Zhang,Ying Zhang,Xiaoxia Zhao,Ping Wen,Di Ma RSC Adv., 2018,8, 19353-19361
• 2. Excimer emission and magnetoluminescence of radical-based zinc(ii) complexes doped in host crystals?
  Shojiro Kimura,Tetsuro Kusamoto Chem. Commun., 2020,56, 11195-11198
• 3. Fast-pulsing NMR techniques for the detection of weak interactions: successful natural abundance probe of hydrogen bonds in peptides?
  Amandine Altmayer-Henzien,Valérie Declerck,David J. Aitken,Ewen Lescop,Denis Merlet,Jonathan Farjon Org. Biomol. Chem., 2013,11, 7611-7615
• 4. Exceptional activity of sub-nm Pt clusters on CdS for photocatalytic hydrogen production: a combined experimental and first-principles study?
  Qiyuan Wu,Shangmin Xiong,Peichuan Shen,Shen Zhao,Alexander Orlov Catal. Sci. Technol., 2015,5, 2059-2064
• 5. Excellent kinetics of single-phase Gd-doped ceria fuel electrodes in solid oxide cells?
  Andreas Nenning,Manuel Holzmann,Jürgen Fleig,Alexander K. Opitz Mater. Adv., 2021,2, 5422-5431

4-Formylpyridine-2-carbonitrile (CAS 131747-70-1): A Versatile Building Block in Organic Synthesis

4-Formylpyridine-2-carbonitrile (CAS 131747-70-1) is a highly valuable heterocyclic compound that has gained significant attention in recent years due to its unique chemical properties and wide range of applications. This pyridine derivative serves as a crucial building block in organic synthesis, particularly in the pharmaceutical and agrochemical industries. The compound features both a formyl group and a nitrile group on its pyridine ring, making it an excellent precursor for various chemical transformations.

The growing interest in 4-formylpyridine-2-carbonitrile can be attributed to its role in developing novel drug candidates and functional materials. Researchers are particularly interested in its potential applications in medicinal chemistry, where it serves as a key intermediate for synthesizing biologically active molecules. Recent studies have explored its use in creating antimicrobial agents, anticancer compounds, and neurological therapeutics, aligning with current healthcare trends and the global focus on developing new treatments for challenging diseases.

From a structural perspective, 4-formylpyridine-2-carbonitrile offers multiple reactive sites that enable diverse chemical modifications. The formyl group at position 4 can participate in condensation reactions, while the nitrile group at position 2 can be transformed into various functional groups such as amides, carboxylic acids, or tetrazoles. This versatility makes it particularly valuable in combinatorial chemistry and high-throughput screening applications, where researchers seek to rapidly generate molecular diversity for drug discovery.

The synthesis of 4-formylpyridine-2-carbonitrile typically involves the Vilsmeier-Haack reaction on appropriate pyridine precursors, followed by careful purification processes to obtain high-purity material. Manufacturers and suppliers emphasize the importance of maintaining strict quality control measures, as the purity of this compound significantly impacts its performance in downstream applications. Analytical techniques such as HPLC, NMR spectroscopy, and mass spectrometry are commonly employed to verify the identity and purity of CAS 131747-70-1 products.

In the field of material science, researchers are exploring the potential of 4-formylpyridine-2-carbonitrile derivatives as components in organic electronic devices and coordination polymers. The compound's ability to form stable complexes with various metal ions makes it attractive for developing new catalysts and sensor materials. These applications align with current trends in sustainable technology and green chemistry, addressing the growing demand for environmentally friendly materials and processes.

The market for 4-formylpyridine-2-carbonitrile has shown steady growth in recent years, driven by increasing research activities in pharmaceutical development and specialty chemicals. Suppliers typically offer this compound in various quantities, from small laboratory-scale amounts to bulk quantities for industrial applications. Proper storage conditions, typically in cool, dry environments protected from light, are essential to maintain the stability of CAS 131747-70-1 over extended periods.

Recent advancements in synthetic methodology have focused on developing more efficient and sustainable routes to produce 4-formylpyridine-2-carbonitrile. These efforts include exploring catalytic processes and green chemistry approaches that minimize waste generation and reduce environmental impact. Such developments respond to the increasing emphasis on sustainable practices in the chemical industry and align with global initiatives for responsible chemical manufacturing.

Quality control remains a critical aspect of working with 4-formylpyridine-2-carbonitrile. Reputable suppliers provide comprehensive analytical data and certificates of analysis to ensure researchers can confidently use this material in their work. The compound's stability, solubility characteristics, and reactivity profile make it suitable for various experimental conditions, though proper handling procedures should always be followed to ensure safety and optimal results.

Looking to the future, 4-formylpyridine-2-carbonitrile is expected to maintain its importance in chemical research and development. Its unique combination of functional groups continues to inspire novel applications in drug discovery, material science, and chemical biology. As synthetic methodologies advance and our understanding of structure-activity relationships deepens, this versatile compound will likely find even broader utility in addressing contemporary scientific challenges.

For researchers seeking reliable sources of CAS 131747-70-1, it's essential to partner with reputable suppliers who can provide high-quality material with consistent performance characteristics. Many suppliers now offer customized solutions, including specialized packaging, purity grades, and technical support to meet the diverse needs of the scientific community working with this valuable chemical intermediate.

• 1620-76-4(4-methylpyridine-2-carbonitrile)
• 29181-50-8(Pyridine-2,4-dicarbonitrile)
• 161233-97-2(2-cyanopyridine-4-carboxylic acid)
• 89538-22-7(2H-Indeno[1,2-c]pyridine-3-carbonitrile, 5-formyl-2-methyl-)
• 98273-47-3(2-cyano-4-Pyridinecarboxamide)
• 18206-06-9(2,6-Dimethylisonicotinaldehyde)
• 131747-68-7(5-formylpyridine-2-carbonitrile)
• 116308-38-4(2-formylpyridine-4-carbonitrile)
• 21635-92-7(4-methyl-2,6-Pyridinedicarbonitrile)
• 63875-01-4(2-methylpyridine-4-carbaldehyde)