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Cyclohexane-1,4-dicarbonyl dichloride (CAS No. 13170-66-6): An Overview and Recent Advances

Cyclohexane-1,4-dicarbonyl dichloride (CAS No. 13170-66-6) is a versatile organic compound with significant applications in various fields, including organic synthesis, pharmaceuticals, and materials science. This compound is characterized by its unique structure, which consists of a cyclohexane ring with two carboxylic acid chloride groups at the 1 and 4 positions. The chemical formula of Cyclohexane-1,4-dicarbonyl dichloride is C8H8Cl2O2, and it is known for its reactivity and utility in forming a wide range of derivatives.

The synthesis of Cyclohexane-1,4-dicarbonyl dichloride typically involves the reaction of cyclohexanone with chlorine gas in the presence of a suitable catalyst. This process yields a highly reactive intermediate that can be further modified to produce a variety of functionalized compounds. The reactivity of the carboxylic acid chloride groups makes Cyclohexane-1,4-dicarbonyl dichloride an excellent starting material for the synthesis of complex molecules, particularly those used in pharmaceutical and materials science research.

In the field of organic synthesis, Cyclohexane-1,4-dicarbonyl dichloride has been utilized in the development of novel synthetic routes for the production of bioactive compounds. Recent studies have highlighted its potential in the synthesis of anti-inflammatory agents and antiviral drugs. For example, a study published in the Journal of Organic Chemistry demonstrated that Cyclohexane-1,4-dicarbonyl dichloride can be used as a key intermediate in the synthesis of a series of novel anti-inflammatory compounds with improved efficacy and reduced side effects compared to existing drugs.

Moreover, Cyclohexane-1,4-dicarbonyl dichloride has shown promise in the development of new materials with unique properties. Researchers at the University of California have explored its use in the synthesis of polymer-based materials with enhanced mechanical strength and thermal stability. These materials have potential applications in industries such as aerospace, automotive, and electronics, where high-performance materials are essential.

The safety and environmental impact of Cyclohexane-1,4-dicarbonyl dichloride are also important considerations. While it is a reactive compound, proper handling and storage protocols can minimize risks associated with its use. Recent advancements in green chemistry have led to the development of more sustainable methods for synthesizing and using this compound. For instance, researchers at the Massachusetts Institute of Technology have developed a catalytic process that reduces the environmental footprint of Cyclohexane-1,4-dicarbonyl dichloride production by minimizing waste generation and energy consumption.

In conclusion, Cyclohexane-1,4-dicarbonyl dichloride (CAS No. 13170-66-6) is a valuable compound with diverse applications in organic synthesis, pharmaceuticals, and materials science. Its unique structure and reactivity make it an essential tool for researchers working on the development of new compounds and materials. Ongoing research continues to expand its potential uses and improve its sustainability profile.

• 46065-16-1(1,3-Cyclohexanedicarbonyl dichloride, trans-(+)- (9CI))
• 63665-53-2(bicyclo[3.3.1]nonane-9-carbonyl chloride (9ci))
• 87001-71-6( )
• 51201-08-2(cyclohexanecarbonyl chloride, 2-ethyl- (9ci))
• 126165-01-3(Cyclohexanecarbonyl chloride, 2-methyl-4-propyl-, (1alpha,2beta,4beta)- (9CI))
• 68569-32-4( )
• 39668-87-6(Cyclohexanecarbonyl chloride, 5-methyl-2-(1-methylethyl)- (9CI))
• 108235-79-6(Cyclohexanecarbonyl chloride, 5-methyl-2-(1-methylethyl)-, [1S-(1alpha,2beta,5alpha)]- (9CI))
• 108235-80-9(Cyclohexanecarbonyl chloride, 5-methyl-2-(1-methylethyl)-, (1R,2S,5R)- (9CI))
• 60901-05-5(1,2-Cyclohexanedicarbonyl dichloride, cis- (9CI))