Cas no 1315571-00-6 (N-3-(Tetramethyl-1,3,2-dioxaborolan-2-yl)phenylpropanamide)

N-3-(Tetramethyl-1,3,2-dioxaborolan-2-yl)phenylpropanamide is a boronic ester derivative featuring a tetramethyl dioxaborolane group attached to a phenylpropanamide scaffold. This compound is primarily valued for its stability and reactivity as a boronate ester, making it a useful intermediate in Suzuki-Miyaura cross-coupling reactions for constructing complex organic frameworks. The tetramethyl dioxaborolane moiety enhances hydrolytic stability compared to simpler boronic acids, facilitating handling and storage. Its amide functionality further allows for potential derivatization or integration into peptidomimetic systems. This reagent is particularly advantageous in medicinal chemistry and materials science, where controlled borylation and functional group compatibility are critical.
N-3-(Tetramethyl-1,3,2-dioxaborolan-2-yl)phenylpropanamide structure
1315571-00-6 structure
Product Name:N-3-(Tetramethyl-1,3,2-dioxaborolan-2-yl)phenylpropanamide
CAS No:1315571-00-6
MF:C15H22BNO3
MW:275.151084423065
MDL:MFCD22493944
CID:2127055
PubChem ID:68573076
Update Time:2025-05-21

N-3-(Tetramethyl-1,3,2-dioxaborolan-2-yl)phenylpropanamide Chemical and Physical Properties

Names and Identifiers

    • N-(3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propionamide
    • N-[3-(Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]propanamide
    • AMTB897
    • JZWCQJQERZDYII-UHFFFAOYSA-N
    • N-[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]propanamide
    • MFCD22493944
    • SCHEMBL3264202
    • AKOS024255634
    • CS-0175892
    • A12009
    • 1315571-00-6
    • 1-Propionylaminobenzene-3-boronic Acid Pinacol Ester
    • DA-12399
    • AS-2939
    • N-3-(Tetramethyl-1,3,2-dioxaborolan-2-yl)phenylpropanamide
    • MDL: MFCD22493944
    • Inchi: 1S/C15H22BNO3/c1-6-13(18)17-12-9-7-8-11(10-12)16-19-14(2,3)15(4,5)20-16/h7-10H,6H2,1-5H3,(H,17,18)
    • InChI Key: JZWCQJQERZDYII-UHFFFAOYSA-N
    • SMILES: O1B(C2C=CC=C(C=2)NC(CC)=O)OC(C)(C)C1(C)C

Computed Properties

  • Exact Mass: 275.1692737g/mol
  • Monoisotopic Mass: 275.1692737g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 20
  • Rotatable Bond Count: 3
  • Complexity: 354
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 47.6

N-3-(Tetramethyl-1,3,2-dioxaborolan-2-yl)phenylpropanamide Security Information

N-3-(Tetramethyl-1,3,2-dioxaborolan-2-yl)phenylpropanamide Pricemore >>

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Additional information on N-3-(Tetramethyl-1,3,2-dioxaborolan-2-yl)phenylpropanamide

N-3-(Tetramethyl-1,3,2-dioxaborolan-2-yl)phenylpropanamide: A Comprehensive Overview

The compound N-3-(Tetramethyl-1,3,2-dioxaborolan-2-yl)phenylpropanamide (CAS No. 1315571-00-6) is a highly specialized organic molecule with significant potential in various fields of chemistry and materials science. This compound has garnered attention due to its unique structural properties and its role in cutting-edge research. In this article, we will delve into the synthesis, applications, and recent advancements associated with this compound.

N-3-(Tetramethyl-1,3,2-dioxaborolan-2-yl)phenylpropanamide belongs to the class of boron-containing organic compounds, which have been extensively studied for their versatile applications in catalysis, electronics, and biotechnology. The presence of the tetramethyl-dioxaborolane group introduces unique electronic and steric properties to the molecule. Recent studies have highlighted its potential as a precursor in the synthesis of advanced materials such as boron nitride nanotubes and graphene analogs.

One of the most notable aspects of CAS No. 1315571-00-6 is its role in organoboron chemistry. Researchers have utilized this compound as a key intermediate in the development of novel catalysts for olefin polymerization and cross-coupling reactions. The ability of this compound to act as a boron-based Lewis acid has opened new avenues in asymmetric catalysis, enabling the synthesis of chiral molecules with high enantioselectivity.

Recent advancements in materials science have also leveraged N-3-(Tetramethyl-1,3,2-dioxaborolan-2-yl)phenylpropanamide for the creation of two-dimensional materials. By incorporating this compound into layered structures, scientists have achieved enhanced mechanical strength and electrical conductivity. These findings suggest promising applications in flexible electronics and energy storage devices.

In the field of biotechnology, CAS No. 1315571-00-6 has been explored for its potential as a bioactive agent. Studies indicate that this compound exhibits selective cytotoxicity against certain cancer cell lines, making it a candidate for further investigation in drug discovery programs. Its ability to interact with specific cellular pathways underscores its potential as a lead compound for therapeutic development.

The synthesis of N-3-(Tetramethyl-1,3,2-dioxaborolan-2-yl)phenylpropanamide involves a multi-step process that combines traditional organic synthesis techniques with modern catalytic methods. Researchers have optimized reaction conditions to achieve high yields and purity levels, ensuring its reliability as a research tool and industrial material.

As the demand for sustainable and high-performance materials continues to grow, compounds like CAS No. 1315571-00-6 are expected to play an increasingly important role in both academic research and industrial applications. Their unique properties and versatility make them invaluable assets in the pursuit of innovative solutions across multiple disciplines.

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